Current jobs related to Process Development Senior Principal Scientist Peptide Chemistry - Cambridge - Amgen


  • Cambridge, Massachusetts, United States VetJobs Full time

    About the RoleWe are seeking a highly skilled and experienced Process Development Principal Scientist to join our team at VetJobs. As a key member of our process development team, you will play a critical role in the development and implementation of analytical methods for the characterization of small molecule, peptide, and oligonucleotide products.Key...


  • Cambridge, Massachusetts, United States VetJobs Full time

    About the RoleWe are seeking a highly skilled and experienced Senior Analytical Scientist to join our Process Development team at VetJobs. As a key member of our team, you will be responsible for leading the development and implementation of analytical methods for the characterization of small molecule, peptide, and oligonucleotide products.Key...


  • Cambridge, United States Amgen Full time

    In this vital role you will work closely with a team of analysts and scientists responsible for the technical aspects of developing analytical tools to gain understanding of key quality attributes in product and process for late phase synthetic small molecule, synthetic peptide, and/or siRNA programs.Our Pivotal Attribute Sciences Department plays a crucial...


  • Cambridge, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever-better products...


  • Cambridge, Massachusetts, United States Sarepta Therapeutics Full time

    About the RoleWe are seeking a highly skilled and experienced Principal Scientist to join our RNA Research group at Sarepta Therapeutics. As a key member of our dynamic and fast-paced chemistry team, you will be responsible for designing and conducting novel oligonucleotide conjugates synthesis, purification, and characterization. You will also apply...


  • Cambridge, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION? If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering...


  • Cambridge, Massachusetts, United States Sarepta Therapeutics Full time

    Unlock the Potential of RNA TherapeuticsSarepta Therapeutics is at the forefront of genetic medicine, with a strong presence in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs). We're seeking a talented scientist to join our dynamic chemistry team in Cambridge, MA, to work on our PMO oligonucleotide platform and discovery...


  • Cambridge, Massachusetts, United States Sarepta Therapeutics Full time

    About the RoleWe are seeking a highly skilled and experienced Senior Research Scientist to join our RNA Chemistry team at Sarepta Therapeutics. As a key member of our team, you will be responsible for designing and conducting novel oligonucleotide conjugates synthesis, purification, and characterization. You will also apply state-of-the-art delivery methods...

  • Scientist, Chemistry

    3 weeks ago


    cambridge, United States Strand Research Full time

    Role: Scientist (Chemistry)THE OPPORTUNITYWe are seeking a Scientist in Chemistry to join our founding team at Strand Research. In this role, you will:Develop novel small molecules and/or macromolecules, including peptides and proteins, for cutting-edge applications in hairLead research conception, planning and execution of studies that support our R&D...

  • Scientist, Chemistry

    3 weeks ago


    cambridge, United States Strand Research Full time

    Role: Scientist (Chemistry)THE OPPORTUNITYWe are seeking a Scientist in Chemistry to join our founding team at Strand Research. In this role, you will:Develop novel small molecules and/or macromolecules, including peptides and proteins, for cutting-edge applications in hairLead research conception, planning and execution of studies that support our R&D...

  • Scientist, Chemistry

    3 weeks ago


    Cambridge, United States Strand Research Full time

    Role: Scientist (Chemistry)THE OPPORTUNITYWe are seeking a Scientist in Chemistry to join our founding team at Strand Research. In this role, you will:Develop novel small molecules and/or macromolecules, including peptides and proteins, for cutting-edge applications in hairLead research conception, planning and execution of studies that support our R&D...

  • Scientist, Chemistry

    3 weeks ago


    Cambridge, United States Strand Research Full time

    Role: Scientist (Chemistry)THE OPPORTUNITYWe are seeking a Scientist in Chemistry to join our founding team at Strand Research. In this role, you will:Develop novel small molecules and/or macromolecules, including peptides and proteins, for cutting-edge applications in hairLead research conception, planning and execution of studies that support our R&D...


  • Cambridge, Massachusetts, United States FogPharma Full time

    About the Role:FogPharma is a pioneering biopharmaceutical company that is revolutionizing the medical possibilities for patients by precisely drugging intracellular targets. As a Senior/Principal Associate Scientist, you will play a key role in our high-throughput multiplexed screening platform, which combines protein biochemistry, combinatorial chemistry,...


  • Cambridge, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology...

  • Research Scientist

    2 weeks ago


    Cambridge, Massachusetts, United States Strand Research Full time

    About the RoleWe are seeking a highly skilled Research Scientist in Chemistry to join our team at Strand Research. As a key member of our founding team, you will play a crucial role in driving our research and development efforts forward.Key ResponsibilitiesDevelop Novel Molecules: Design, synthesize, and characterize novel small molecules and...


  • Cambridge, Massachusetts, United States Flagship Ventures Full time

    {"title": "Principal Scientist, Protein Sciences", "company": "Flagship Ventures", "description": "Company OverviewFlagship Ventures is a pioneering technology company that leverages artificial intelligence to transform the scientific method. Our mission-driven team is dedicated to discovering and developing innovative solutions for the life sciences...


  • Cambridge, Massachusetts, United States Flagship Ventures Full time

    Transform Human Health and SustainabilityFlagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. We are seeking a talented and highly motivated Principal Scientist, Medicinal Chemistry to join our team.Key ResponsibilitiesDesign and...


  • Cambridge, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION? You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s...


  • Cambridge, Massachusetts, United States Flagship Ventures Full time

    Company OverviewFlagship Ventures is a pioneering technology company that leverages artificial intelligence to transform the scientific method. As a privately held, early-stage company, we are backed by Flagship Pioneering, which provides the resources and vision needed to achieve groundbreaking results.Job SummaryWe are seeking a highly skilled Principal...


  • Cambridge, Massachusetts, United States Newton Colmore Full time

    About the RoleWe are seeking a highly experienced Senior DMPK and ADME Expert to join our research team at Newton Colmore. As a Principal Scientist in Drug Development, you will play a key role in designing and implementing in vivo PK studies, providing updates and results to research teams, and presenting strategies at governance interactions.Key...

Process Development Senior Principal Scientist Peptide Chemistry

4 months ago


Cambridge, United States Amgen Full time

HOW MIGHT YOU DEFY IMAGINATION?

If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever–better products that reach over 10 million patients worldwide. Its time for a career you can be proud of.

Process Development Senior Principal Scientist Peptide Chemistry (Synthetics)

Live

What you will do

Lets do this. Lets change the world. Amgen is seeking a dedicated Process Development Senior Principal Scientist with industry experience in peptide synthesis and manufacturing to join our Drug Substance Technologies – Synthetics (DSTS) group in Cambridge, MA. Amgens DSTS group within Process Development (PD) is responsible for the invention, development, and implementation of drug substance manufacturing processes and technologies to advance Amgen's portfolio of synthetic and hybrid assets. The Senior Principal Scientist role will include leading a multidisciplinary team of chemists and chemical engineers in the development of efficient and sustainable manufacturing processes for peptide synthesis and purification, driving technology innovation in the areas of chemical and microbial recombinant peptide production technologies, and providing technical expertise as well as developing and mentoring staff within the organization. The successful candidate for this role will be a people–centered leader with expertise in peptide process development and manufacturing with a consistent track record of scientific innovation and leadership within the pharmaceutical industry.

Key Responsibilities:

Lead a multidisciplinary project team in the development of sustainable and cost–effective processes for peptide manufacturingDrive technology innovation in the areas of chemical and microbial recombinant peptide production technologiesSupport cGMP manufacturing and technology transfer to large–scale peptide production facilitiesDevelop strategies to ensure process performance through process understanding, modeling and characterizationGuide successful completion of project deliverables and ensure timelines are metWork multi–functionally to deliver regulatory documents and support regulatory filingsServe as a technical expert and keep current in the field of peptide synthesis and manufacturingCoach and provide career and scientific / technical advice to colleagues within the organization

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek will possess these qualifications.

Basic Qualifications:

Doctorate degree PhD OR PharmD OR MD in Chemistry, Chemical Engineering, or Biochemistry/Chemical Biology and 3 years of industry experienceOr

Masters degree in Chemistry, Chemical Engineering, or Biochemistry/Chemical Biology and 6 years of industry experienceOr

Bachelors degree n Chemistry, Chemical Engineering, or Biochemistry/Chemical Biology and 6 years of industry experience

Preferred Qualifications:

6+ years in the pharmaceutical industry with expertise in peptide process development and manufacturing (solid–phase peptide synthesis, liquid–phase peptide synthesis, site–selective peptide modification, semisynthetic approaches, chemoenzymatic peptide synthesis)Ability to work within a dynamic and interdisciplinary environment to achieve resultsPeople–centered leadership skills in building strong teams through mutual trust and respect and exhibits Amgen leadership attributes of inspire, accelerate, integrate, and adaptTrack record of publications, patents and presentations

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well–being.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.A discretionary annual bonus program, or for field sales representatives, a sales–based incentive planStock–based long–term incentivesAward–winning time–off plans and bi–annual company–wide shutdownsFlexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.