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Research Associate-ADME

4 months ago

Hayward, United States Frontage Lab Full time

Company: Frontage Labs., Inc.

Division/Department: QDI

Reports to: VP, ADME

Full-time

Location: Hayward, CA

Job/Req.

Job Summary

Quintara Discovery (QDI), a wholly owned subsidiary of Frontage Laboratories in the San Francisco Bay Area, is a dynamic and growing biopharma CRO with a proven track record of working with leading biopharmaceutical companies, emerging start-up companies, universities and leading research institutes.

We are looking for a highly-motivated Research Associate to develop and conduct biochemical and cellular assays to evaluate potential therapeutics. Experience in cell line development, ELISA, PBMC biomarker, cell culture, cellular assays, gene expression is desirable. Prior experience in ADME assays including metabolite stability, drug transporter, CYP450, PPB and measurements of physicochemical properties is preferred. The candidate needs to be proficient in assay design, trouble-shooting, data analysis and working with 96-w & 384-w plate-based assays. The candidate needs to have a good understanding of drug discovery processes and experience in a discovery project is preferred. This position requires working with an interdisciplinary team of DMPK scientists, analytical chemists and pharmacologists.

* Knowledge with LC/MS/MS is a plus.
* Ability to design, execute, analyze and interpret experiments with minimal direct supervision.
* Attention to detail.
* Excellent communication and organizational skills.
* Ability to multi-task and follow through any given tasks.
* Positive and collaborative disposition with the ability to work cooperatively within a team
* Perform cell biology and molecular biology studies to support early drug discovery projects

Essential Duties & Responsibilities

List below the major areas of responsibility of the job in descending order of importance (most important to least important). Indicate the approximate percentage of time spent on each responsibility (note the total of all percentages must equal 100%, 3-5 responsibilities is normal but may vary). Under each responsibility, summarize the specific duties required to perform the job. Give as much detail as necessary to fully explain the job and consider:

* Whether the reason the job exists is to perform that function and whether removing the function would fundamentally change the job;
* Whether serious consequences would arise if someone in this job is not required to perform a particular function/s;
* The number of employees available to perform the function or among whom the function can be distributed; and,
* The degree of expertise or skill required to perform the function.

% of Time

Duties & Responsibilities

50%

Perform experiments according to study protocols

25%

Analyze experimental data

10%

Ability to troubleshoot and solve basic technical and instrumental issues

10%

Writing up protocols and reports under supervision

5%

Perform project communication with client, study director, and project management team under supervision

100%

Minimum Job Requirements & Qualifications

Describe the minimum level of formal education and experience required to successfully perform the job

as well as any required certification, licensure or registration. KSAs may include language requirements, required computer ability, communications skills, etc.

Educational/Training Requirement:

BS/MS in biology, biochemistry and other related fields

Experience:

3+ years industrial experience in related scientific fields

Licenses/Certifications (if applicable):

Knowledge, Skills, and Abilities (KSAs):

Supervisory Responsibility

List the job titles that directly report to this job (formal supervision).

Travel Requirements

Estimate the percentage and nature (i.e., domestic or international) of travel; if no travel is required, indicate 0%). 0%

Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.

Americans with Disabilities Act (ADA)

PHYSICAL DEMANDS and work environment CHECKLIST

PHYSICAL DEMANDS

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. These may include lifting, pushing, climbing, degree of eyestrain, sitting for extended periods of time, prolonged standing, etc. Frequency refers to the amount of time one is engaged in the activity; please estimate time by checking the appropriate boxes.

Physical Demands

Physical Demand

None

Rarely

Occasionally

Frequently

Constantly

Weight

Standing

x

Walking

x

Sitting

x

Lifting

x

Up to 10 pounds

Carrying

x

Up to 10 pounds

Pushing

x

Choose weight

Pulling

x

Choose weight

Climbing or balancing

x

Stooping, kneeling, crouching

or crawling

x

Reaching with hands/arms

x

Using hands to finger, handle, grasp or feel

x

Talking

x

Hearing

x

Tasting or smelling

x

Repetitive motions

x

Seeing

x

* Note: Any special physical demands should be clearly communicated to any applicants applying for this job and all employees occupying this job.

Does this job have any special vision requirements? Check all that apply.

Close vision (clear vision at 20 inches or less)

Distance vision (clear vision at 20 feet or more)

x Color vision (ability to identify and distinguish colors)

Peripheral vision (ability to observe an area that can be seen up and down or to the left and right while eyes are fixed on a given point)

Depth perception (three-dimensional vision, ability to judge distances and spatial relationships)

x Ability to adjust focus (ability to adjust the eye to bring an object into sharp focus)

No special vision requirements

WORK ENVIRONMENT

Work environment characteristics described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Describe in the box below:

* If a job is required to work or irregular hours (overnight, weekends, overtime, etc.);
* Any hazardous or unusual conditions associated with the physical environment this job works in (outside, in inclement weather, exposure to toxic materials, etc.);
* Other unusual working conditions like extreme deadlines, pace of work, noise, etc.; and,
* How often or for how long someone in this job is exposed to these conditions.