Senior Research Associate

2 weeks ago

Hayward, United States Frontage Laboratories Full time
Job DescriptionJob Description

Title: Senior Research Associate

Location: Hayward, Ca (on-site)

Reports to: Group Leader—Assay Development at Quintara Discovery, part of Global Drug Discovery Services at Frontage Labs

Classification: Full-time

Frontage Laboratories Inc. is an award winning, publicly listed (HKSE), full-service CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China, and growing over 30% YOY. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.

Position/Job Summary:

We have an opening for a Senior Research Associate that has worked extensively with a broad range of biochemical, cellular, and molecular assay instrumentation and technology used in drug discovery. Experience with robotic liquid handling, magnetic particle processors, multi-drops, plate washers, plate readers (fluorescence, luminescence, absorbance, electrochemiluminescence), electrophoresis, microfluidics, conventional and real-time thermal cyclers, as applied to medium to high throughput screening, would be helpful. The assays we rely on most to answer clients’ biological questions include ELISA, MSD, Flow Cytometry, RNA extraction for gene expression, and enzyme activity. An understanding of how these assays work, the data the abovementioned technologies deliver, and how to troubleshoot a variety of issues will be critical to success. You will work with an interdisciplinary team of DMPK scientists, pharmacologists, and analytical chemists dedicated to delivering accurate data in support of early-phase drug discovery projects. This is a lab-based position that will require flexibility, efficiency, creativity, a collaborative spirit, and “can-do” attitude.

Roles & Responsibilities:

  • Design and implement instrument protocols for various automated liquid handlers according to client needs and in collaboration with scientists and research associates.
  • Review aberrant data with colleagues to help identify issues that may be addressed by changes to instrumentation.
  • Troubleshoot instrument errors.
  • Coordinate service requests with vendors if instrument failure persists.
  • Maintain lab equipment (including freezers) in good working order.
  • Aid in lab organization and sample management projects

As needed:

  • Learn and run defined protocols for various 96-well and 384-well plate-based assays.
  • Analyze results using in-house and client-developed templates.
  • Discuss experimental design and results with colleagues.
  • Maintain a lab notebook.
  • Assist with preparing informal and formal protocols and reports.
  • Other duties, as assigned.

Education, Experience & Skills Required:

  • Bachelor’s degree in cell biology, biochemistry, or related field. Master’s degree preferred.
  • Industry-based lab experience required.
  • At ease using liquid handling equipment and other forms of automation.
  • Prior experience developing assays with colorimetric, luminescence, and fluorescence readouts as well as multi-color flow cytometry preferred.
  • Understanding of drug discovery processes.
  • Excellent organization, planning, and communication skills.
  • Critical attributes: attention to detail, curiosity, self-starter, and self-motivated.

Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.

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