Senior Scientist, Cell Based Assay

2 weeks ago

Emeryville, United States Metagenomi Full time

Metagenomi is a gene editing company committed to developing potentially curative therapeutics by leveraging a proprietary toolbox of next-generation gene editing systems to accurately edit DNA where current technologies cannot. Our metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. We adapt and forge these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific and have a decreased risk of immune response. These systems fuel our pipeline of novel medicines and can be leveraged by partners. Our goal is to revolutionize gene editing for the benefit of patients around the world.

Whether it's the biological diversity of our gene editing systems or the people that help discover them, Metagenomi celebrates the diversity of life. This is achieved through a compassionate culture that acknowledges the dimensions of our diversity. We know that when people feel a sense of inclusion and belonging in the workplace, they have a safe space to bring creativity and innovation to everything they do. We are intentional about building and maintaining a culture where people are valued and respected, there is equity in opportunities, and our respective opinions and differences matter.

We are hiring a Senior Scientist, Cell-Based Assay (Contract) for the ASQC team. Reporting to a Principal Scientist, this position will contribute to developing and qualifying cell-based potency assays, including mRNA, AAV, and LNP release and characterization assays. This role will be based in Emeryville, California.

How you'll contribute:

* Develop cell-based assays to support process development and production lot testing
* Execute method development, transfer, qualification, and in-house testing for final product and in-process materials
* Author and review SOPs, study design and protocols, technical protocols and reports, method transfer plan and reports
* Maintain accurate and complete documentation of any scientific experimental plan, data, and reports
* Operate under Good Documentation Practice for efficient data management and retrieval
* Follow the required regulatory standards, conform to company policies and standard operating procedures (SOPs)
* Present analytical data reports clearly and concisely to senior management, including test performance metrics and trends
* Meet changing project demands to support process development and manufacturing activities
* Manage multiple tasks, prioritize project work, and effectively use available resources to meet agreed timelines.

Must haves:

* An undergraduate degree, an advanced degree preferred, in a cell and Molecular biology-related field
* At least five years of closely related industry experience in cell-based assay development and qualification
* Hands-on experience in tissue culture and cell-based assay (general tissue culture, cell banking, cell proliferation, electroporation, transfection, transduction, flow cytometry, AAV, and ELISA)
* Experience and knowledge with gene and cell therapy, mRNA/LNP, CRISPR/Cas technology
* The ability to manage multiple priorities simultaneously
* Collaborative, committed and solutions-oriented

California Pay Transparency Disclosure:

This position is classified as a non-exempt hourly position under the Federal Labor Standards Act. The anticipated hourly rate for this position will be $77.00. Please note that individual total compensation for this position will be determined at the Company's sole discretion and may vary based on location, skill level, years and depth of relevant experience, and education.

#LI-NG1

What makes Metagenomi a unique place to work?

* We are passionate about developing technologies derived from microbial-rich ecosystems that have the power to enable therapeutic development and the potential to cure devastating diseases.
* We have cultivated an amazing culture that values teamwork, curiosity, scientific rigor, and fun. We have a strong commitment to work/life balance, host a weekly employee happy hour and events, provide catered lunches and endless snacks, and more
* We offer competitive compensation, including a market-benchmarked salary, annual target bonus potential, equity, comprehensive benefits plan, 401(k) with company matching, retirement safe harbor plan, and other perks.



At Metagenomi, we know that our people drive our success. We are an equal opportunity employer and believe in and value diversity and inclusion. Metagenomi provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term careers. Metagenomi does not discriminate on the basis of race, color, religion, sexual orientation, gender, age, physical or mental disability, or any other status protected under federal, state, or local law.

Applicants/Employees have rights under various State and Federal Employment Laws, including without limitation:

* Family & Medical Leave Act
* Equal Employment Opportunity Commission
* Employee Polygraph Protection Act
* California Family Rights Act
* California Fair Employment and Housing Act

Notice to agencies: Our in-house Talent Acquisition Team manages all employment opportunities at Metagenomi. Agencies and independent recruiters must be approved as a vendor by Metagenomi's Talent Acquisition team. To protect the interests of all parties, Metagenomi will not accept unsolicited resumes, profiles, or biographies. Any unsolicited resumes sent to Metagenomi will be considered referrals and the property of Metagenomi.

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