Director, Vector Production
2 weeks ago
The Director, Vector Production will oversee activities related to the Process Development and in-house non-GMP/cGMP production of recombinant Adeno-associated Viral Vectors (rAAV), and cGMP vector production at contract manufacturing organizations (CMOs).
ESSENTIAL FUNCTIONS:
- Manage the Process Development, GMP production, testing and fill finish of rAAV products at CMO's
- Manage internal activities related to the scale-up and production of rAAVs in house for use in R&D and pending facility decisions
- Lead in-house team producing rAAV
- Co-ordinate production activities with research, non-clinical development, QA, QC and clinical development
- Ensure the ongoing security of the supply chain for raw materials and intermediates to ensure the uninterrupted performance of rAAV operations
- Co-ordinate the transfer, qualification and implementation of process improvements and scale-up
- Lead the reporting, investigation and resolution of deviations encountered during GMP production activities
- Participate in the design, construction and commissioning of company manufacturing facilities
- Other activities as may be assigned
EDUCATION, EXPERIENCE AND SKILLS REQUIREMENTS:
The ideal candidate for this position will have in-depth experience of the large-scale cGMP production of rAAV, including upstream cell culture, downstream processing, and fill finish operations.
Candidate must possess:
- MS or Ph.D in bioprocessing, chemical engineering, vector biology, or biological sciences
- Minimum of 10 years experience in the biotechnology or pharma industry with a primary focus on upstream cell culture process development and manufacturing operations for biologics
- Proven track record of managing in-house and CMO GMP production operations
- In-depth experience with:
- Mammalian cell, insect cell and microbial cell culture systems at both pilot-scale and at large-scale
- Different bioreactor production systems and scales, including disposable-based culture systems
- CIP, SIP, WFI
- In-depth knowledge of FDA, EMA, GMP and ICH regulatory requirements
- Knowledge of Quality Systems and QBD as they relate to GMP production operations and process optimization
- Experience of facility, and production equipment design and validation, including IQ, OQ & PQ a plus
- Proven managerial skills
- Outstanding organizational skills
- Excellent written and oral communication skills
- Ability to operate in a fast-paced, multi-disciplinary industrial environment
The successful candidate will enjoy a competitive base salary and the opportunity to participate in incentive compensation programs, including bonus and stock option plans. Sangamo offers a comprehensive benefits program, including: medical, dental and vision care; paid vacation and holiday time; access to a voluntary 401(k) and Employee Stock Purchase Plan. Sangamo is an equal opportunity employer.
Please send your resume/CV and a cover letter that specifically addresses this job posting as email attachments to: jobs@sangamo.com
-
Director, Vector Production
4 weeks ago
Richmond, United States Sangamo Therapeutics Full timeJOB SUMMARY: The Director, Vector Production will oversee activities related to the Process Development and in-house non-GMP/cGMP production of recombinant Adeno-associated Viral Vectors (rAAV), and cGMP vector production at contract manufacturing organizations (CMOs). ESSENTIAL FUNCTIONS: Manage the Process Development, GMP production, testing and fill...
-
Project Director
4 weeks ago
Richmond, California, United States Vector Consulting, Inc Full timeOur client is seeking a seasoned Project Director to lead a hybrid 9+ months renewable contract role in a government agency in Richmond, VA.About the Role:The successful candidate will work in the agency Project Management Office as a Project Director. The position will be responsible for project management services for a variety of agency initiatives that...
-
Information Technology Support Analyst
2 weeks ago
richmond, United States Vector Consulting, Inc Full timeOur government client is looking for an experienced IT Support Analyst on a 6+ months renewable contract role in Richmond, VA.Position – IT Support AnalystNotes:* Interviews will be conducted ONSITE, NO exceptions* Candidates MUST be able to work ONSITE 100%JOB DESCRIPTION:The agency is seeking a local candidate for an on-site technical support position....
-
Information Technology Support Analyst
2 weeks ago
richmond, United States Vector Consulting, Inc Full timeOur government client is looking for an experienced IT Support Analyst on a 6+ months renewable contract role in Richmond, VA.Position – IT Support AnalystNotes:* Interviews will be conducted ONSITE, NO exceptions* Candidates MUST be able to work ONSITE 100%JOB DESCRIPTION:The agency is seeking a local candidate for an on-site technical support position....
-
Information Technology Support Analyst
2 weeks ago
Richmond, United States Vector Consulting, Inc Full timeOur government client is looking for an experienced IT Support Analyst on a 6+ months renewable contract role in Richmond, VA.Position – IT Support AnalystNotes:* Interviews will be conducted ONSITE, NO exceptions* Candidates MUST be able to work ONSITE 100%JOB DESCRIPTION:The agency is seeking a local candidate for an on-site technical support position....
-
Director of Product Strategy
1 week ago
Richmond, United States CapTech Full time#xa 0;Role Overview: CapTech is seeking a dynamic and experienced Product Manager to join our team. This role is a unique blend of product strategy, product marketing, and product management, with a strong emphasis on developing and launching innovat Director, Strategy, Product Manager, Marketing Manager, Product, Leadership, Technology
-
Director of Product Strategy
1 week ago
Richmond, United States CapTech Full time#xa 0;Role Overview: CapTech is seeking a dynamic and experienced Product Manager to join our team. This role is a unique blend of product strategy, product marketing, and product management, with a strong emphasis on developing and launching innovat Director, Strategy, Product Manager, Marketing Manager, Product, Leadership, Technology
-
Product Support Director
4 weeks ago
Richmond, California, United States Chesapeake Search Partners Full timeOverview:Chesapeake Search Partners is seeking a Product Support Director to lead the parts and service departments. This role will oversee and collaborate with managers to drive performance optimization, strengthen customer relationships, and streamline product support operations.Key Responsibilities:Provide strategic leadership and support to service,...
-
Product Marketing Director- Data Products
2 days ago
Richmond, United States Dynata Full timeThe Opportunity: Dynata is looking for an experienced product marketing leader to lead us through the next stages of product growth. As a Product Marketing Director, you will be responsible for articulating the value of our full product portfolio, building compelling product positioning and messaging, and creating sales enablement and marketing campaigns. We...
-
Maintenance Director
4 weeks ago
Richmond, Indiana, United States Dairy Farmers of America Full timeMaintenance DirectorThe Maintenance Director at Dairy Farmers of America provides strategic leadership and direction to the plant maintenance function of a 24-hour, 7-day-a-week operation. This role oversees supervisory responsibilities in accordance with the Company's policies, OSHA regulations, and applicable laws. The Maintenance Director may directly...
-
Director of Product Management
6 months ago
Richmond, United States CoStar Group Full timeResponsibilities : Shape & manage the product roadmap Drive product releases in a fast-paced Agile software development environment. This includes writing user stories (requirements), prioritizing releases, maintaining a product roadmap and backlog, and creating release notes. Work closely with senior executives, UI design, engineering, QA,...
-
Director of Product Strategy
1 week ago
Richmond, United States CapTech Consulting Full timeCompany Description CapTech is an award-winning consulting firm that collaborates with clients to achieve what's possible through the power of technology. At CapTech, we're passionate about the work we do and the results we achieve for our clients. From the outset, our founders shared a collective passion to create a consultancy centered on strong...
-
Director of Product Strategy
7 days ago
Richmond, United States CapTech Consulting Full timeCompany Description CapTech is an award-winning consulting firm that collaborates with clients to achieve what's possible through the power of technology. At CapTech, we're passionate about the work we do and the results we achieve for our clients. From the outset, our founders shared a collective passion to create a consultancy centered on strong...
-
Project Director
4 weeks ago
Richmond, California, United States National Computer Systems Full timeJob SummaryWe are seeking a highly skilled Project Director to lead our project team in delivering high-quality projects on time and within budget. The ideal candidate will have a strong background in project management, excellent communication skills, and the ability to work effectively in a team environment.Key ResponsibilitiesDevelop and implement project...
-
Richmond, United States Capital One Full timeCenter 1 (19052), United States of America, McLean, VirginiaDirector, Product Security-Information Security OfficeAt Capital One, you will help consult on initiatives, programs, and projects to raise their game in Information Security and Risk Management. You are pragmatic and practical in your understanding of risk and security, but also willing to know...
-
Sales Director
4 weeks ago
Richmond, Virginia, United States Jobot Full timeJob Title: Sales DirectorJobot is seeking a seasoned Sales Director to lead our nationwide sales team. As a key member of our leadership team, you will be responsible for developing and implementing effective sales strategies that align with our business goals.Responsibilities:Lead a team of sales professionals to achieve sales targetsEstablish and maintain...
-
Manufacturing Director
4 weeks ago
Richmond, California, United States Air Liquide Full timeJob Summary:As a key member of the Air Liquide team, the Manufacturing Director will be responsible for overseeing the day-to-day operations of our manufacturing plant. This includes ensuring the production of high-quality products, maintaining a safe working environment, and meeting regulatory requirements.Key Responsibilities:Oversee the production process...
-
Service Director
3 weeks ago
Richmond, California, United States Moore CadillacSubaru of Richmond Full timeMoore Subaru/Cadillac of Richmond is seeking an experienced Service Director to lead our team. We are excited to have begun construction on our new state-of-the-art facility. This opportunity has the potential to be the highest paid Service Director position in the Greater Richmond market, earning $200,000 plus. The ideal candidate will have dealership...
-
Director of Development
4 weeks ago
Richmond, Virginia, United States The Endowment Project Full timeAbout The Endowment ProjectThe Endowment Project is a dynamic, mission-driven social enterprise that empowers public high schools to achieve sustainable excellence through alumni and community development and fundraising. Our goal is to build for public high schools in the US the same fundraising infrastructure that fuels US colleges and private high...
-
Service Director
2 weeks ago
richmond, United States Moore CadillacSubaru of Richmond Full timeMoore Subaru/Cadillac of Richmond is seeking an experienced, energetic Service Director to lead our team. We are very excited to have begun construction on our new state-of-the-art facility. This opportunity has the potential to be the highest paid Service Director position in Greater Richmond market earning $200,000 plus. Candidate must have dealership...