Senior Formulations Scientist
2 months ago
ABOUT ELEKTROFI
Elektrofi is revolutionizing the delivery of biologic therapies by giving patients the ability to control how they want to receive and benefit from life-changing medicines. Our breakthrough ultra-high concentration microparticle technology platform resolves the limitations associated with intravenously biologic therapies by enabling convenient at-home subcutaneous self-administration. With a focus on monoclonal antibodies, therapeutic proteins, and other large molecule drugs, we create, develop, and commercialize subcutaneous biologic therapies in collaboration with strategic partners. We believe a patient-centered healthcare approach can lead to a healthier world. We are headquartered in Boston and innovate globally. We are Formulating the Future of BiologicsTM.
POSITION SUMMARY
Elektrofi is seeking talented individuals to join our company full-time as Senior Scientist, Formulation Development to play a key role in the development of Elektrofi’s platform formulation technology. Selected individuals will join a dynamic, multidisciplinary team of scientists and contribute to a variety of IND-enabling formulations activities in a highly collaborative environment.
KEY RESPONSIBILITIES
- Lead the development of novel, ultra-high concentration, microparticle suspension products with our large biopharmaceutical partners for a wide range of therapeutic biologic modalities using QbD principles.
- Identify high-leverage opportunities that push the boundaries of the Elektrofi’s formulation platform and improve workflow efficiency to meet critical corporate objectives.
- Spearhead the development of appropriate scaled-down process models, stress conditions, and experimental methodology to optimize drug product performance along the dimensions of protein stability, dissolution quality, processability, suspension physical stability, and in-vivo performance.
- Work closely with process development, device, analytical, and translational development teams to identify formulation dependencies on product performance.
- Act as the subject matter expert on protein stability and formulation. Represent the formulation development function on cross-functional CMC project teams.
- Author relevant sections in regulatory submissions (IND, DMF, BLA, etc.) and technology transfer documentation. Manage relevant method protocols, data, and reports.
MINIMUM QUALIFICATIONS
- Ph.D. (0 to 2-year experience) in Pharmaceutical Sciences, Chemical Engineering, Biochemistry, Biophysics, Bioengineering, Medicinal Chemistry, Polymer Chemistry, Pharmaceutical Engineering, or a related field required.
- Experience with high concentration protein formulation development and UF/DF cycle optimization is desirable.
- Strong scientific ideation skills and resourcefulness in testing hypotheses.
- Knowledge of statistical methods and design of experiments methodology.
- Sharp laboratory acumen and organizational skills.
- Demonstrated expertise in one or more of the following areas of research is highly desirable:
- Microparticle processing and particle engineering approaches.
- Formulation development of protein therapeutics.
- Strong grasp of pharmacological concepts and a fundamental understanding of drug product development.
- Ability to work independently and in multi-disciplinary teams.
- Attention to detail and the ability to thoroughly document experimental work.
- Familiarity with standard office software (MS Office, Teams, SharePoint, JMP).
Our unique strength lies in transforming pioneering ideas into concrete, life-transforming solutions. To realize this ambitious vision, we are dedicated to nurturing an in-office work ethos. While remote work has its merits, it does not constitute a fundamental aspect of our working approach. As part of our commitment to enhancing the in-office experience, we provide all employees with a commuter assistance program, offering support of up to $315 per month. Please apply at elektrofi.com/careers.
EEOC Statement:
Elektrofi provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.
To all agencies, please, no phone calls or emails to any employee of Elektrofi about this requisition. All resumes submitted by search firms/employment agencies to any employee at Elektrofi via email, the internet, or in any form and method will be deemed the sole property of Elektrofi unless such search firms/employment agencies were engaged by Elektrofi for this requisition and a valid agreement with Elektrofi is in place. If a candidate submitted outside of the Elektrofi agency engagement process is hired, no fee or payment of any kind will be paid.
The candidate must be authorized to work in the US.
-
Senior Scientist 1
3 weeks ago
Boston, United States Amplitude Therapeutics Full timeCompany summary:Amplitude Therapeutics is a seed-staged biotechnology company focusing on developing the next generation of RNAs to fully unlock the therapeutic potential of RNA biology. We are founded by leaders in the RNA and non-viral therapy fields and backed by premier Biotech VCs.Position summary:Amplitude Therapeutics is seeking a highly motivated...
-
Scientist / Senior Scientist
2 months ago
Boston, United States Elektrofi Full timeOur breakthrough ultra-high concentration microparticle technology platform resolves the limitations associated with intravenously biologic therapies by enabling convenient at-home subcutaneous self-administration.Elektrofi is looking for a Translational Scientist/ Senior Scientist to support the development of the novel Elektrofi formulation platform.The...
-
Scientist / Senior Scientist
2 months ago
Boston, Massachusetts, United States Elektrofi Full timeOur breakthrough ultra-high concentration microparticle technology platform resolves the limitations associated with intravenously biologic therapies by enabling convenient at-home subcutaneous self-administration.Elektrofi is looking for a Translational Scientist/ Senior Scientist to support the development of the novel Elektrofi formulation platform.The...
-
Sr. Scientist, Formulation
2 weeks ago
Boston, United States Kelonia Therapeutics Full timeHere at Kelonia Therapeutics, we aren't just a preclinical company; we're trailblazers in viral engineering, pushing the boundaries of in vivo lentiviral gene and cell therapy. We're not just a team; we're dreamers on a mission to bring the promise of cell and gene therapy to every patient in need.At Kelonia, we've gathered a group of pioneers in cell and...
-
Director, Formulation
4 days ago
Boston, United States Vertex Pharmaceuticals Incorporated Full timeJob DescriptionGeneral Summary:Vertex is seeking a talented individual to join our Formulation Development group in Boston, MA. Formulation Development group is a fast paced and high energy environment.The Director in Formulation Development will lead the advancement of drug candidates from exploratory development through commercial line extension in a...
-
Senior Research Associate, LNP Formulation
2 months ago
Boston, United States Commonwealth Sciences, Inc. Full timeSenior Research Associate, LNP FormulationContract position located in Boston, MAResponsibilities of the Senior Research Associate, LNP Formulation:Routinely formulate high-quality lipid nanoparticles (LNP).Perform detailed biophysical characterization of LNPs by Dynamic Light Scattering, Fluorescence Spectroscopy, and HPLC to measure LNP size,...
-
Senior Research Associate, LNP Formulation
2 months ago
Boston, United States Commonwealth Sciences, Inc. Full timeSenior Research Associate, LNP FormulationContract position located in Boston, MAResponsibilities of the Senior Research Associate, LNP Formulation:Routinely formulate high-quality lipid nanoparticles (LNP).Perform detailed biophysical characterization of LNPs by Dynamic Light Scattering, Fluorescence Spectroscopy, and HPLC to measure LNP size,...
-
Senior Scientist Analytical Development
1 week ago
Boston, United States AL Solutions Full timeJob DescriptionJob DescriptionWe are looking for an experienced Senior Scientist in Analytical Development specializing in Radiopharmaceuticals to join our innovative team. In this role, you will lead the development and validation of analytical methods to support the characterization and quality control of radiopharmaceutical products.Key...
-
Senior Environmental Engineer/Scientist
2 weeks ago
Boston, Massachusetts, United States The Vertex Companies, LLC Full timeJob OverviewThe Vertex Companies, LLC is on the lookout for a Senior Environmental Engineer/Scientist to spearhead the development and execution of comprehensive assessment and remediation initiatives across New England. Our clientele encompasses a wide range of stakeholders, including private developers, property owners, legal representatives, and various...
-
Senior Scientist, Analytical Development
4 weeks ago
Boston, United States Elektrofi Inc Full timeJob DescriptionJob DescriptionDescription:ABOUT ELEKTROFI Elektrofi is revolutionizing the delivery of biologic therapies by giving patients the ability to control how they want to receive and benefit from life-changing medicines. Our breakthrough ultra-high concentration microparticle technology platform resolves the limitations associated with...
-
Senior Scientist, Analytical Development
2 weeks ago
Boston, United States Elektrofi Inc Full timeJob DescriptionJob DescriptionDescription:ABOUT ELEKTROFI Elektrofi is revolutionizing the delivery of biologic therapies by giving patients the ability to control how they want to receive and benefit from life-changing medicines. Our breakthrough ultra-high concentration microparticle technology platform resolves the limitations associated with...
-
Junior Analytical Scientist
2 weeks ago
Boston, Massachusetts, United States Elektrofi Inc Full timeJob OverviewABOUT ELEKTROFIElektrofi is at the forefront of transforming the administration of biologic therapies, empowering patients with the choice of how they receive essential medications. Our innovative ultra-high concentration microparticle technology addresses the challenges associated with traditional intravenous biologic therapies, facilitating...
-
Junior Analytical Scientist
7 days ago
Boston, Massachusetts, United States Elektrofi Inc Full timeJob OverviewABOUT ELEKTROFIElektrofi is at the forefront of transforming the administration of biologic therapies, empowering patients with the choice of how they receive essential medications. Our innovative ultra-high concentration microparticle technology addresses the challenges of traditional intravenous biologic therapies, facilitating convenient...
-
Boston, United States Entrada Therapeutics Full timeThe Organization What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible. Our Endosomal Escape Vehicle (EEV™)-therapeutics are designed to enable the...
-
Boston, United States Verve Therapeutics, Inc. Full timeJob DescriptionJob DescriptionThe CompanyVerve is a clinical-stage genetic medicines company established with a mission to solve the global health epidemic of cardiovascular disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene-editing, Verve is pioneering a new approach to the care of cardiovascular disease,...
-
Associate Analytical Scientist
2 months ago
Boston, United States Elektrofi Inc Full timeJob DescriptionJob DescriptionDescription:ABOUT ELEKTROFIElektrofi is revolutionizing the delivery of biologic therapies by giving patients the ability to control how they want to receive and benefit from life-changing medicines. Our breakthrough ultra-high concentration microparticle technology platform resolves the limitations associated with intravenously...
-
Senior Scientist, Discovery
3 months ago
Boston, United States PepGen Full timeJob DescriptionJob DescriptionPosition SummaryWe are seeking an Senior Scientist, Discovery who will report to our Senior Director, Discovery Biology. They will be responsible for executing biochemical and cellular assays to support drug discovery efforts. The ideal candidate will be experienced with the testing of chemical compounds, data analysis and...
-
Scientist II/Senior Scientist, Biochemistry
3 months ago
Boston, United States NextRNA Therapeutics Full timeAs a Scientist II / Senior Scientist, Biochemistry at NextRNA Therapeutics, you will join an interdisciplinary team of highly creative and talented individuals whose vision is to improve patients’ lives by expanding the space of RNA-targeted Therapies. You will be a key team member responsible for integrating biochemical technologies with our drug...
-
Junior Analytical Scientist
7 days ago
Boston, Massachusetts, United States Elektrofi Inc Full timeJob OverviewABOUT ELEKTROFIElektrofi is at the forefront of transforming the administration of biologic therapies, empowering patients with the choice of how they receive essential medications. Our innovative ultra-high concentration microparticle technology addresses the challenges associated with traditional intravenous biologic therapies, facilitating...
-
Stablix - Senior Scientist, Medicinal Chemistry
2 months ago
Boston, Massachusetts, United States Stablix, Inc Full timeStablix- Senior Scientist, Medicinal ChemistryStablix is a venture-backed preclinical stage drug discovery company, pioneering an entirely new field of targeted deubiquitination therapeutics to bring transformative medicines to patients with high unmet medical need.We are a creative and multidisciplinary team of scientists, innovators and leaders dedicated...