Technical Development Scientist II

7 days ago


Hillsboro, United States BEPC Inc. - Business Excellence Professional Consulting Full time

BEPC is looking for a Technical Development Scientist II in South San Francisco, CA to join our fast-growing team of consultants

W2 Contract: 12 months with opportunities for extensions based on business needs and performance.

Pay Range: $48.00-62.11/hr. plus we offer Medical, Dental, Vision and Life Insurance benefits

Schedule: 100% Onsite


Job Knowledge & Scope:


RMG, in the Cell Culture and Bioprocess Operations department, is responsible for providing support to pre-Early-Stage Research to Early Development projects with high-throughput protein production from mammalian transient cultures. We are looking for a motivated candidate with cell culture and sterile technique experience to join our team to enable protein production and help advance our portfolio.


Key Responsibilities:


  • Perform transient transfections in CHO and HEK293 cells in scales 1mL to 25L to support
  • pipeline productions adhering to established protocols.
  • Maintain seed train cell cultures in bioreactors and shake flasks.
  • Operate liquid handlers - Tecan and Hamilton for automated processes.
  • Operate wave bag reactors for productions and cell maintenance.
  • Maintain and troubleshoot key cell culture instruments such as Vi-Cell, Nova Flex2, Nova Flex, Cedex and bioreactors.
  • Participate in troubleshooting production or platform processes.
  • Participate in lab management and data management.
  • Contribute to improving existing cell culture platforms and developing new platforms to
  • deliver diverse protein and cellular reagents to enable a large number of research programs.


The candidate must be highly self-motivated, organized, detail oriented and responsive to feedback. The candidate is expected to precisely follow written procedures, practice sterile technique, demonstrate accurate documentation skills, and report deviations in a timely manner. They should be able to work independently within guidelines and policies, with minimal guidance.


Qualifications Required:


  • PhD (with 0-2yrs relevant experience) in Biotechnology, Chemistry, Biochemistry or related fields.
  • Suspension adapted mammalian cell culture (CHO and/or HEK293).
  • Excellent written and verbal communication skills and have strong collaborative skills.


Preferred:


  • State-of-the-art transient and stable protein expression experience.
  • Relevant bioreactor experience.
  • Hands-on experience with automation and liquid handlers like Tecan Freedom Evo and
  • Hamilton Microlab Star.
  • Knowledge of cell biology, cell engineering, molecular biology, recombinant protein
  • purification and protein characterization is preferred.


USOPS



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