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Senior Research Development Scientist

3 months ago


Pleasanton, United States Tailored Management Full time

Sr. Scientist (Next-Generation Sequencing)

Location: 4300 Hacienda Drive, Pleasanton, CA 94588


Position Summary:

The Sequencing Workflows and Applications team at * is seeking an experienced Sr. Scientist to join our research and early development efforts in Next-Generation Sequencing (NGS). The ideal candidate will bring a strong background in NGS workflow optimization and hands-on experience with nucleic acid extraction, library preparation, target enrichment, sequencing, and data analysis. This is a key role within our team, contributing to the development of new reagents, workflows, and assay solutions in the rapidly evolving field of NGS.


Key Responsibilities:

  • Design, optimize, and validate NGS-based workflows, contributing to cutting-edge research in molecular biology and human disease.
  • Accurately document experimental methods, materials, and results in electronic laboratory notebooks. Analyze data, evaluate results, and determine the next steps for experiments.
  • Utilize broad molecular biology knowledge to troubleshoot assays, resolve technical issues, and interpret data.
  • Present scientific background information and project updates at internal and cross-functional team meetings. Establish and maintain productive relationships with Development personnel, and train new R&D staff as needed.
  • Write and implement standard operating procedures (SOPs) to ensure consistency and accuracy in experimental processes.


Minimum Qualifications:

Educational Background: Bachelor’s degree in Biological/Life Sciences, Chemistry, Biochemistry, or related field.


Experience:

  • BS with 6+ years or MS with 3+ years of relevant industry experience.
  • Strong background in molecular biology, with a focus on NGS methods.
  • Proven experience in assay design, optimization, validation, experimental design, data analysis, and presentation.
  • Hands-on experience with NGS methods, including exome sequencing, whole genome sequencing, and RNA sequencing.


Preferred Qualifications:

  • Experience using Illumina instruments (NovaSeq, HiSeq, NextSeq, MiSeq).
  • Previous experience in the analysis and interpretation of NGS data.
  • Familiarity with different genomics analysis technologies such as microarrays, real-time PCR, and quality control validation equipment.
  • Understanding of oncology biology is a plus.