Scientist I, Analytical Development

3 weeks ago


Mountain View, United States IGM Biosciences, Inc. Full time

We seek an experienced, hands-on individual to join our analytical team in the role of Scientist I. In this role, you will support late-stage analytical method development, IgM characterization, and manufacturing process development activities for the IGM biotherapeutics portfolio. You must have expertise in liquid chromatography and capillary electrophoresis, be able to drive projects to completion, communicate, be organized, multi-task, and enjoy working in a dynamic/team-oriented environment.


Responsibilities:

  • Develop late-stage analytical methods for HPLC-based applications (SEC, RP) and Capillary electrophoresis-based applications (CE-SDS, cIEF) that support US and ex-US drug product release.
  • Design, lead, and execute collaborative characterization studies to support critical quality attribute (CQA) assignments for IgM antibodies.
  • Support method transfers across internal departments as well as external CROs.
  • Perform basic analytics, including Spectroscopy (UV-VIS/A280), compendial methods, Gels (SDS-PAGE, Western Blot), and other biophysical methods.
  • Support routine testing for process development, formulation development, and stability studies.
  • Operate and help maintain lab equipment, including but not limited to UV-VIS, HPLCs, and CE instruments.
  • Support sample shipping, progress tracking, receiving, and inventory.
  • Maintain an organized, analytical lab environment, complying with Fed and Cal safety regulations.
  • Prepare lab plans and record experiments using an Electronic Lab Notebook.
  • Prepare buffers and handle protein samples with aseptic techniques.
  • Help prepare SOPs, protocols, and technical documents.
  • Analyze scientific/technical data and present data in project team meetings.


Qualifications:

  • Level commensurate with experience.
  • Biochemistry, Chemistry, Biology, or related background, BS with 10+ years, MS with 5+ years of hands-on Bioanalytical Lab experience, preferably in the biotech/biopharmaceutical settings.
  • Strong expertise in HPLC and Capillary electrophoresis-based applications is a must.
  • Experience with Spectroscopy, Gels, and biophysical techniques is required.
  • Experience with biologics and aseptic sample handling is required.
  • Able to work efficiently on multiple projects simultaneously.
  • Willingness to learn new skills.
  • Strong interpersonal and communication skills are a must.
  • Able to lift up to 20 lbs and work at the lab bench for extended periods.
  • Must be able to commute to Mountain View.
  • We offer a fast-paced, collaborative, team-based work environment.



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