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Associate Scientist

2 months ago

Spring House, United States Insight Global Full time

We seek a motivated and high performing individual to work with the Cell Therapy group within Therapeutics Discovery (TD) to support the development of autologous and allogeneic cell therapy products through handling plasmid construct generation requests. In this role you will intake generation requests and work to oversee and execute the entire cloning, prep, and QC process until ultimate hand-off of completed plasmids to functional teams. The successful candidate will have a strong background in molecular biology and exceptional organizational skills. Success in this position will require both the ability to independently execute responsibilities and collaborate within a cross-functional department. This role is an exciting opportunity to be part of a diverse and ambitious discovery team working to create life-changing therapies for patients.


Job Responsibilities:

  • Work with cell therapy scientists to intake construct generation requests
  • Coordinate and oversee plasmid cloning and prep at external CROs
  • Perform laboratory work, including cloning, plasmid mini/midi/maxi prep, QC analytical methods such as quantification, PCR, sequencing, restriction digests, gel electrophoresis
  • Register and inventory plasmids in virtual and physical databases
  • Coordinate hand-off of plasmids to internal functional teams
  • Analyze data and effectively communicate results
  • Identify and troubleshoot technical challenges
  • Maintain laboratory records and ensure compliance with laboratory protocols and safety procedures


Qualifications

Bachelor’s Degree in Molecular Biology or related field


Experience and Skills

Skills Required:

  • Background in molecular biology techniques
  • Experience designing plasmid cloning strategies and performing plasmid cloning and mini/midi/maxi prep
  • Experience running plasmid QC analytical methods such as quantification, PCR, sequencing, restriction digests, and gel electrophoresis
  • Ability to autonomously perform lab- and computer-based responsibilities with limited guidance
  • Ability to collaborate with colleagues and handle multiple simultaneous requests
  • Self-motivated with excellent organizational and time management skills

Preferred Skills:

  • Experience designing lentiviral vectors and/or non-viral expression systems for human cells
  • Experience working in a role responsible for supporting multiple project teams