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Research Scientist

2 months ago

Boston, Massachusetts, United States Merck Full time

Job Description

The Quantitative Biosciences Department at our Company's Research Laboratories is seeking a highly motivated Scientist to join our In-Vivo Pharmacology group at the Longwood Innovation Center in Boston. The successful candidate will be responsible for developing disease models, planning / designing and execution of in-vivo pharmacologic or mechanistic studies using disease models, collection / analysis of data, and report writing in support of research & development programs in immunology and oncology therapeutic areas.

Primary Responsibilities:

  • Plan, design and execute in-vivo pharmacological experiments to support and advance drug discovery programs in immunology and oncology.
  • Characterize and optimize in vitro, ex vivo or in vivo assays at scale to support potential compound screening, biomarker identification and mechanism of action studies.
  • Run validation and research operating plan (ROP) assays for test articles with appropriate benchmarks.
  • Maintain timely, accurate laboratory records of activities & comply with good documentation practices.
  • Effectively collaborate with integrated teams in a matrix organization setting to facilitate the conduct of studies and to the success of discovery programs.

Education Minimum Requirements:

  • M.S. in pharmacology, immunology, biotechnology or biology, with 1+ years or B.S. with 3+ years of relevant in-vivo experience, preferably in a pharmaceutical/ biotechnology setting.

Required Experience and Skills:

  • Hands-on experience with in-vivo models – particularly related to autoimmune disease or tumor immunology.
  • Working knowledge using standard data analysis tools such as Graph Pad Prism, FlowJo, etc., and Microsoft programs.
  • Excellent written and interpersonal communication skills and the ability to collate the results and make a presentation to the stakeholders.
  • The ability to work independently, as well as collaboratively with peers within and across departments is expected.

Preferred Experience and Skills:

  • Experience in PK/PD models, autoimmune/tumor efficacy experience.
  • ELISA, Western blot, and flow cytometry and other immunological assay skills are desired.

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

#EligibleforERP

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement​

Pay Transparency Nondiscrimination

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

No

Travel Requirements:

No Travel Required

Flexible Work Arrangements:

Not Applicable

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

OEB4, OEB5, BSL2

Job Posting End Date:

07/17/2024

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Job Posting End Date:07/17/2024

A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R301837