Scientist, in Vivo Pharmacology
4 weeks ago
An exciting opportunity is available for a Scientist to join the In Vivo Pharmacology & Biomarker Discovery team of the Institute of Medicine (IOM) at Altos Labs.We are seeking a dedicated and highly skilled Scientist for our In Vivo Pharmacology Operations.The successful candidate will be supporting the progression of our therapeutic programs by conducting and optimizing in vivo research activities and successful execution of preclinical studies.Lead the in vivo pharmacology aspect of multiple projects within the Institute of Medicine, providing in vivo pharmacology and physiology expertisePlan, execute and manage in vivo studies (in both mice and rats), including protocol development, dosing and tissue collection, study monitoring, bio sample management, tissue processing and relevant data analysisDevelop, characterize and implement new animal models to improve the effectiveness of in vivo pharmacology studiesBroad and extensive expertise with all aspects of in vivo rodent research (various dosing routes, anesthesia, surgical procedures, necropsy, tissue processing, etc.)Hands-on experience with cell biology techniques (RNA/DNA extraction, PCR, Western Blot, ELISA, small molecule/biologics interventional assays)
-
Senior Scientist, PET Biology
1 month ago
San Diego, California, United States AlzForum Foundation Inc Full timeIts work requires deep scientific expertise in many disciplines including chemistry, radiochemistry, cellular and molecular pharmacology, enzymology, and imaging technologies coupled with an ability to work collaboratively with internal and external partners.It is currently seeking an outstanding individual to join our team as senior scientist biology &...
-
Job Staff Scientist
1 month ago
San Diego, California, United States WOLFRAM Full timeJob] Staff Scientist- Modeling & Simulation [Takeda] The Modeling and Simulation scientist will be responsible for modeling support for the Takeda portfolio in the preclinical translational (PKPD and Systems Pharmacology) group.Identifies and champions novel scientific approaches to develop innovative applications of modeling and simulation to biology,...
-
Senior Scientist, Cell
1 month ago
San Diego, California, United States Pharmaron Full timeThe Senior Scientist will play a pivotal role by supporting in vivo studies to test cell and gene therapy treatments.The Senior Scientist serves as Study Director and is responsible for the oversight and conduct of in-vivo studies involving the testing of pharmaceutical compounds and cell and gene therapy.The Study Director functions as a key member of the...
-
San Diego, California, United States Takeda Full timeJoin Takeda as a Research Scientist II, Inflammation Discovery Research where you will be empowered to design, execute and analyze discovery immunology and in vitro preclinical pharmacology studies of inflammation and autoimmunity with a focus on TYK2 inhibition for multiple disease indications.You will also identify and implement new assay technologies that...
-
Associate Director
1 month ago
San Diego, California, United States Escient Pharmaceuticals Full timeThe Senior Scientist, Translational Biology and Drug Discovery leads and contributes to the implementation and analysis of translational biology, in vitro and in vivo pharmacology for validation of multiple targets.Leads and supports the team to generate and test novel experimental hypotheses to advance discovery-based research and development in mast cell...
-
Director, DMPK
4 weeks ago
San Diego, California, United States Crinetics Pharmaceuticals, Inc Full timeThe Director, DMPK will report to the Vice President of DMPK and will primarily liaise with our highly dynamic Chemistry, Pharmacology, and Toxicology departments to develop strategies and advance discovery programs to the clinic.The individual should have strong scientific training in all areas of DMPK and a demonstrated track record of leading focused DMPK...
-
Associate Scientist
4 weeks ago
South San Francisco, California, United States Amgen Full timeThe Associate Scientist at Amgen conducts a variety of routine laboratory tasks and procedures. They assist with data collection and basic analysis under the supervision of more senior scientists.Key Responsibilities:Design and perform in vitro studies to assess the biology of novel targets and evaluate mechanisms of action of therapeutic...
-
Senior Director, Clinical Pharmacology
5 days ago
South San Francisco, California, United States Maze Therapeutics Full timeThe Position:At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for a Senior Director, Clinical Pharmacology to join our Clinical Science team and take a central role in pioneering the future of...
-
Senior Director, Clinical Pharmacology
4 weeks ago
South San Francisco, California, United States Maze Therapeutics Full timeThe Position:At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for a Senior Director, Clinical Pharmacology to join our Clinical Science team and take a central role in pioneering the future of...
-
Principal Scientist
2 days ago
San Francisco, California, United States Nurix Therapeutics Full timeAbout the PositionWe are seeking a talented and highly motivated individual with a strong background in synthetic organic chemistry to join our medicinal chemistry group in the pursuit of novel small molecules to treat patients with unmet medical needs. The successful candidate may lead a project team and/or a group of medicinal chemists and will engage in...
-
Scientist, Oligonucleotide Chemistry
4 weeks ago
San Diego, California, United States Johnson & Johnson Full timeJanssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Scientist, Oligonucleotide Chemistry (Synthesis)-RNA, Gene Therapy & Delivery located in La Jolla, CA. At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex...
-
Senior Scientist
1 month ago
San Diego, California, United States Genesis Therapeutics Full timeThey will also utilize the Genesis Therapeutics platform and assist medicinal chemistry efforts in drug discovery programs from Hit ID through candidate nomination.Use SBDD principles, optimize physiochemical properties, interpret in vitro and in vivo ADME/PK/Toxicology data, and understand in vitro and in vivo biology data to drive programs.Work with other...
-
Executive Director, Immunology
1 month ago
San Francisco, California, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Senior Director, DMPK
1 month ago
San Diego, California, United States Vertex Pharmaceuticals, Inc Full timeVertex San Diego Drug Metabolism and Pharmacokinetics (DMPK) team is seeking a highly motivated, experienced scientist and leader Senior Director level to help advance discovery and development of transformational therapies for serious unmet medical needs.The Senior Director of Drug Metabolism & Pharmacokinetics will be part of the global DMPK and local site...
-
Staff Research Scientist
1 month ago
San Francisco, California, United States Gladstone Institutes Full timeCategory:ScienceLab/Area:Akassoglou LabDescription:The Akassoglou Lab at The Gladstone Institutes is seeking a highly skilled imaging-oriented engineer to join our group as a Staff Research Scientist-Imaging Engineer. The mission of the position is to develop technologies to investigate the interactions between the immune, vascular and nervous systems with...
-
Scientist, Medicinal Chemistry
1 month ago
San Francisco, California, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Director, DMPK
4 weeks ago
San Francisco, California, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Bioinformatics Engineer I/II
4 weeks ago
South San Francisco, California, United States Gordian Biotechnology Full timeDo you want to be part of a brilliant team, using single-cell genomics to forge new paths in drug discovery? At Gordian, we combine unique large-scale in vivo perturbation screens with novel analysis approaches to identify therapeutic targets for complex diseases with unmet medical need.The Destination:Gordian Biotechnology is a therapeutics company whose...
-
SRA – Cell Biology and Immunology
3 days ago
San Francisco, California, United States Nurix Therapeutics Full timePositionNurix is seeking a passionate and accomplished biologist to join our mission of unlocking the therapeutic potential of E3 ubiquitin ligases in oncology and immunology. As a key member of our dynamic Discovery Biology team, you'll play a pivotal role in uncovering new small molecule degraders that hold the key to unlocking novel therapeutic avenues,...
-
Scientist - in Vivo Pharmacology - Preclinical
4 weeks ago
San Diego, United States Capricor Inc Full time**Position**:Scientist - In vivo Pharmacology - Preclinical **Responsibilities**: - Work with the Associate Director, providing in vivo pharmacology expertise. - Plan, execute and manage in vivo studies, including protocol development, dosing and tissue collection, study monitoring, bio sample management, tissue processing and relevant data analysis. -...
-
Associate Scientist
3 weeks ago
San Diego, United States BioPhase Full timeAssociate Scientist / Senior Research Associate, In-vivo pharmacology Part-time ~ 20 hours a weeksome weekend work includedindefinite contract Required Education and Experience:B.S. / M.S. in Biology (or Immunology/Pharmacology/Immuno-Oncology or related) with 9+ years of industry /CRO drug discovery experience in any therapeutic area.Ability to managing...
-
Associate Scientist
3 weeks ago
San Diego, United States BioPhase Full timeAssociate Scientist / Senior Research Associate, In-vivo pharmacology Part-time ~ 20 hours a weeksome weekend work includedindefinite contract Required Education and Experience:B.S. / M.S. in Biology (or Immunology/Pharmacology/Immuno-Oncology or related) with 9+ years of industry /CRO drug discovery experience in any therapeutic area.Ability to managing...
-
Senior Scientist
2 days ago
San Diego, United States BioPhase Full timeAre you a highly self-motivated, dynamic scientist passionate about cancer immunotherapy? We're looking for a Scientist II/Senior Scientist to join our team and report directly to the Director of Pharmacology. In this role, you'll be at the forefront of groundbreaking research, deeply involved in planning and executing in vitro and in vivo studies to define...
-
Senior Scientist
20 hours ago
San Diego, United States BioPhase Full timeAre you a highly self-motivated, dynamic scientist passionate about cancer immunotherapy? We're looking for a Scientist II/Senior Scientist to join our team and report directly to the Director of Pharmacology. In this role, you'll be at the forefront of groundbreaking research, deeply involved in planning and executing in vitro and in vivo studies to define...
-
Scientist, In Vivo Physiology
3 weeks ago
South San Francisco, United States NewLimit Full timeCompany info NewLimit is a biotechnology company working to radically extend human healthspan. We're developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning...
-
Scientist, In Vivo Physiology
3 weeks ago
South San Francisco, United States NewLimit Full timeCompany infoNewLimit is a biotechnology company working to radically extend human healthspan. We're developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning...
-
Sr. Scientist, Translational Biology
4 weeks ago
San Diego, United States Zentalis Full timeJob DescriptionJob DescriptionSalary: $125-148kJOB SUMMARY: Responsible for leading research on translational projects focused on small molecule drug combinations and understanding MoA. Generate robust datasets that will have a direct impact on our oncology drug discovery process and drug pipeline.ESSENTIAL DUTIES AND RESPONSIBILITIES:Design, conduct, and...
-
Veterinary Research Scientist
4 weeks ago
San Diego, United States RPM ReSearch Full timeJob DescriptionJob DescriptionJob Title: Veterinary Research ScientistPrimary Responsibilities:This position requires a broad knowledge of the anatomy and physiology of small and large animals to help develop and support in vivo models to screen therapeutics and devices being developed for various disorders. Experience with surgical, dosing and sampling...
-
Director, Preclinical Pharmacology
1 month ago
South San Francisco, United States SiteOne Therapeutics, Inc. Full timeAbout SiteOneSiteOne Therapeutics is a biopharmaceutical company developing treatments for hypersensitivity disorders of the nervous system such as pain, cough and epilepsy. Our values are scientific rigor, intensity, teamwork and commitment to our shared mission of developing transformative medicines for the benefit of patients. Our drug candidates are...
-
Director, Preclinical Pharmacology
4 weeks ago
South San Francisco, United States SiteOne Therapeutics, Inc. Full timeAbout SiteOneSiteOne Therapeutics is a biopharmaceutical company developing treatments for hypersensitivity disorders of the nervous system such as pain, cough and epilepsy. Our values are scientific rigor, intensity, teamwork and commitment to our shared mission of developing transformative medicines for the benefit of patients. Our drug candidates are...
-
Director, Preclinical Pharmacology
4 weeks ago
South San Francisco, United States SiteOne Therapeutics, Inc. Full timeAbout SiteOneSiteOne Therapeutics is a biopharmaceutical company developing treatments for hypersensitivity disorders of the nervous system such as pain, cough and epilepsy. Our values are scientific rigor, intensity, teamwork and commitment to our shared mission of developing transformative medicines for the benefit of patients. Our drug candidates are...
-
Ocular Research Scientist
4 weeks ago
San Diego, United States RPM ReSearch Full timeJob DescriptionJob DescriptionResearch Scientist/Study Director OcularDescription: We are seeking to find an accomplished Ocular Scientist with requirements of a broad knowledge of Ocular anatomy, physiology, and biochemistry to help develop and support in vivo models to screen small molecule, cell/gene therapy, as well as large molecule therapeutics and...
-
San Diego, United States Scientific Search Full timeHead of RNA Pharmacology and Translational Sciences Location: San DiegoIndustry: Biotech (SiRNA)Therapeutic Area: Metabolic DisordersOur startup biotech client with incredible technology and deep pockets has tasked Scientific Search in finding them a We are seeking a Head of Pharmacology and Translational Sciences to build and lead a team focusing on design...
-
Head of Pharmacology and Translational Sciences
1 month ago
San Diego, United States Scientific Search Full timeHead of RNA Pharmacology and Translational Sciences - RNA Location: San DiegoIndustry: Biotech (SiRNA)Therapeutic Area: CardiovascularOur startup biotech client with incredible technology and deep pockets has tasked Scientific Search in finding them a We are seeking a Head of Pharmacology and Translational Sciences to build and lead a team focusing on design...
-
Director, Clinical Pharmacology
3 weeks ago
San Diego, United States Equillium, Inc. Full timeThe Director of Clinical Pharmacology will lead the development and implementation of clinical pharmacology strategies for small molecules and biologics within the company's portfolio. They will offer expertise in analyzing pharmacokinetics, absorption, distribution, elimination profiles, dose selection rationale, drug/food interaction potential, and QT...
-
In Vivo Research Associate
3 weeks ago
San Mateo, United States The Fountain Group LLC Full timeImmediate Opportunity for a Research Associate located in Foster City, CA (Onsite). Details for the position are as follows: Job Description: We are seeking a highly motivated in vivo research associate to join our Inflammation group as a contractor. The selected candidate will support in vivo scientists to execute preclinical studies, whether...
-
Director, Clinical Pharmacology
2 weeks ago
San Diego, United States Equillium Full timeThe Director of Clinical Pharmacology will lead the development and implementation of clinical pharmacology strategies for small molecules and biologics within the company's portfolio. They will offer expertise in analyzing pharmacokinetics, absorption, distribution, elimination profiles, dose selection rationale, drug/food interaction potential, and QT...
-
Sr. Scientist I, Biology
2 days ago
San Diego, United States RayzeBio Full timeJob Title: Sr. Scientist, BiologyLocation: San DiegoNH: R6BackgroundRayzeBio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of targeted...
-
Sr. Scientist I, Biology
2 days ago
San Diego, United States RayzeBio Full timeJob Title: Sr. Scientist, BiologyLocation: San DiegoNH: R6BackgroundRayzeBio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of targeted...