Scientist, Oligonucleotide Chemistry
Found in: beBee jobs US - 2 weeks ago
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at .
RNA, Gene Therapy & Delivery is an organization within Therapeutics Discovery, committed to the delivery of high-quality drug candidates in the novel synthetic modalities space working closely with Janssen Therapeutic Areas (TA) discovery teams. Our mission requires critical thinking, a portfolio approach and deep scientific expertise in several fields including oligonucleotide chemistry, bioconjugation chemistry, nanotechnology, cellular and molecular pharmacology and screening technologies coupled with an ability to work collaboratively with internal and external partners. This role offers tremendous growth opportunity within a dynamic and science driven organization.
Key Responsibilities:
- Lead efforts to support the synthesis of oligonucleotides and bioconjugates for delivery.
- In collaboration with the team, support oligonucleotide innovation, optimization and process development efforts.
- Support the optimization of chemistry processes for solid phase synthesis, purification, analysis of oligonucleotides and bioconjugates.
- Critically evaluate experiment data and communicate scientific findings as verbal presentations and written reports, and provide updates on project status.
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Director, Computational Chemistry
Found in: beBee jobs US - 2 weeks ago
San Diego, California, United States Biopharma Company Full timeAs the ASSOCIATE/DIRECTOR, COMPUTATIONAL CHEMISTRY, you will work as part of a multi-disciplinary team of Medicinal Chemists, Computational Chemists, Structural biologists, Pharmacologists and Biologists to provide Computational expertise to advance drug discovery projects.You will contribute to drug discovery efforts across various modalities including...
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Principal Scientist, Peptide Protein Chemistry
Found in: beBee jobs US - 2 weeks ago
San Diego, California, United States Oculus Search Partners Full timePrincipal Scientist, Peptide Protein Chemistry Direct HirePrincipal Scientist, Peptide Protein Chemistry This BioPharma is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options.Proficient in all aspects of modern peptide synthesis, protein bioconjugation, peptide and protein...
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Research Associate I
Found in: beBee jobs US - 2 weeks ago
San Diego, California, United States Adarx Pharmaceuticals Inc Full timeWe are seeking a highly motivated and qualified individual to join our Discovery Chemistry-Oligonucleotide Team as a Research Associate I-II and work as part of a team to drive success.We are looking for candidates as Research Associate I or II, Oligonucleotide Chemistry to join our discovery chemistry team to advance cutting-edge RNA editing drug discovery...
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Director / Senior Director, Computational Chemistry
Found in: beBee jobs US - 2 weeks ago
San Diego, California, United States X4lifesciences Full timeWith a focus on leveraging cutting-edge machine learning and interdisciplinary approaches, they are committed to advancing drug discovery and development to improve patient outcomes worldwide.We are seeking a highly experienced and motivated Director/Senior Director of Computational Chemistry to lead a team of computational scientists in their world class...
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Quality Control Stability Specialist
Found in: beBee jobs US - 2 weeks ago
San Diego, California, United States Avidity NanoMedicines Full timeAvidity is revolutionizing the field of RNA with its proprietary AOCs, which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies.Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by...
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Scientist, Medicinal Chemistry
Found in: beBee jobs US - 2 weeks ago
San Francisco, California, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
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AD / Sr. Principal Scientist - CADD
Found in: beBee jobs US - 2 weeks ago
San Diego, California, United States Novartis Full timeAD/Sr. Principal Scientist - CADDThe Computer-Aided Drug Discovery (CADD) group in San Diego is seeking an AD/Senior Principal Scientist to join our talented and innovative drug discovery team.Initiate drug discovery efforts by proposing novel targets / modalities, evaluating target druggability and executing in silico hit generation, triage and expansion...
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Senior Scientist, PET Biology
Found in: beBee jobs US - 2 weeks ago
San Diego, California, United States AlzForum Foundation Inc Full timeIts work requires deep scientific expertise in many disciplines including chemistry, radiochemistry, cellular and molecular pharmacology, enzymology, and imaging technologies coupled with an ability to work collaboratively with internal and external partners.It is currently seeking an outstanding individual to join our team as senior scientist biology &...
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Scientist, DNA-Encoded Library
Found in: beBee jobs US - 1 week ago
San Diego, California, United States Johnson & Johnson Full timeJanssen Research & Development, LLC, a member of Johnson & Johnson's Family of Companies, is recruiting for a Scientist, DNA-Encoded Library - Discovery Chemistry, located in San Diego, CA. At Janssen, we never stop working toward a future where disease is a thing of the past. We're the Pharmaceutical Companies of Johnson & Johnson, and you can count on us...
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Scientist, Bioanalytical
Found in: beBee jobs US - 3 weeks ago
San Diego, California, United States Neurocrine Biosciences Full timein collaboration with AbbVieThe Bioanalytical Scientist, as part of the DMPK, Preclinical Development team, will develop and perform assays to quantify large molecule therapeutics in biological fluids and tissues.The qualified individual will be responsible for the implementation of various types of immunoassays (e.g., ELISA and electrochemiluminescence),...
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Clinical Laboratory Scientist. Job in San Diego WestCoast-Jobs
Found in: beBee jobs US - 3 weeks ago
San Diego, California, United States Kaiser Permanente Full timeJob Summary: Performs pre-analytical, analytical and post-analytical phase testing of all complexities as defined by Clinical Laboratory Improvement Act/Amendment (CLIA) to include specialized tests and analysis in one or more areas of clinical laboratory such as Hematology, Microbiology, Clinical Chemistry, Urinalysis, Immunohematology, Serology,...
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Staff Scientist
Found in: beBee jobs US - 3 weeks ago
San Francisco, California, United States Proclinical Full timeStaff Scientist - Formulation - Permanent - OnsiteProclinical Staffing is seeking a Staff Scientist - Formulation to join a clinical-stage biopharmaceutical company. This is a permanent role located in San Francisco, CA.Primary ResponsibilitiesThe role of staff scientist within the formulation group is to support preclinical studies for discovery projects as...
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Associate Scientist Peptide Chemistry SF Bay Area
Found in: beBee jobs US - 3 weeks ago
South San Francisco, California, United States Vilya, Inc. Full timeVilya is a computational biotechnology company creating a novel class of medicines to precisely target disease biology. We believe computational approaches are an integral, if not foundational, component of drug discovery and development. Our platform is built on ground-breaking research in advanced computational approaches and taps into uncharted chemical...
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Senior Scientist
Found in: beBee jobs US - 2 weeks ago
San Diego, California, United States Genesis Therapeutics Full timeThey will also utilize the Genesis Therapeutics platform and assist medicinal chemistry efforts in drug discovery programs from Hit ID through candidate nomination.Use SBDD principles, optimize physiochemical properties, interpret in vitro and in vivo ADME/PK/Toxicology data, and understand in vitro and in vivo biology data to drive programs.Work with other...
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Associate Scientist II
Found in: beBee jobs US - 2 weeks ago
South San Francisco, California, United States Collabera Full timeOperate and maintain analytical and preparative scale HPLC instrumentation.Purification of samples from medicinal chemistry projects on a milligram to gram scale by preparative HPLC.Maintain and troubleshoot NMR spectrometer under the guidance of senior scientists.Hands-on experience with analytical HPLC, preparative HPLC, mass spectrometry, and/or...
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Enzyme Development Scientist
Found in: beBee jobs US - 4 days ago
San Diego, California, United States Hologic Full timeJob DescriptionAs a leading innovator of women's health, we at Hologic are empowering people to live healthier lives everywhere, every day.R&D is the engine of our business here at Hologic, our R&D teams sit at the cutting edge of technology, our innovations are designed to achieve exceptional clinical results making it possible to detect, diagnose and treat...
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Director, DMPK
Found in: beBee jobs US - 2 weeks ago
San Diego, California, United States Crinetics Pharmaceuticals, Inc Full timeThe Director, DMPK will report to the Vice President of DMPK and will primarily liaise with our highly dynamic Chemistry, Pharmacology, and Toxicology departments to develop strategies and advance discovery programs to the clinic.The individual should have strong scientific training in all areas of DMPK and a demonstrated track record of leading focused DMPK...
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Scientific Lead, Biophysical Chemistry
Found in: beBee jobs US - 2 weeks ago
San Francisco, California, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
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Scientist, CMC Analytical Development
Found in: beBee jobs US - 2 weeks ago
South San Francisco, California, United States Alumis Inc. Full timeAlumis is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.The Alumis team is seeking a highly motivated Contract...
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Clinical Laboratory Scientist. Job in San Jose WestCoast-Jobs
Found in: beBee jobs US - 1 week ago
San Jose, California, United States Kaiser Permanente Full timeJob Summary: Under the general direction of the Laboratory Director, or their designee, performs pre-analytical, analytical and post-analytical procedures and analyses to provide data for health maintenance, diagnoses, treatment and monitoring of medical conditions. Enhances quality of patient care and service through interdepartmental cooperation and...