Senior Scientist

2 weeks ago

San Diego, United States BioPhase Full time

Are you a highly self-motivated, dynamic scientist passionate about cancer immunotherapy? We're looking for a Scientist II/Senior Scientist to join our team and report directly to the Director of Pharmacology. In this role, you'll be at the forefront of groundbreaking research, deeply involved in planning and executing in vitro and in vivo studies to define new drug candidates' pharmacokinetics (PK) and pharmacodynamics (PD) properties. As a leader from the bench, you'll have the opportunity to participate in all aspects of the drug discovery and development process, from program conception to IND-enabling studies. The ideal candidate will have a solid background in pharmacology and pre-clinical drug development, with specific experience in immuno-oncology and working with biologics, particularly immune-cell engagers. We're seeking enthusiastic, highly motivated individuals who thrive in collaborative environments and are eager to play a vital role in our dedicated and positive R&D team.


We want to hear from you if you're ready to make a difference in cancer immunotherapy and contribute to developing novel therapeutic proteins Apply now and join us on this exciting journey towards improving patient outcomes.


Responsibilities:

  • Independently design, conduct, and analyze complex experiments with minimal supervision to support target validation efforts and pharmacology strategies to evaluate drug candidates in vitro and in vivo.
  • Contribute new ideas and concepts aligned with project strategies and identify relevant assays and experimental protocols to test hypotheses.
  • Build and maintain relationships with external CROs for cell-based and translational assays.
  • Document, interpret, and present results to diverse audiences.
  • Drive innovative science and effectively communicate and collaborate within cross-functional teams.


Qualifications:

  • Ph.D. degree in pharmacology, cancer biology, immunology, or similar, with 2+ years experience in drug development (industry experience preferred)
  • Expertise in immunology, tumor biology, and pharmacology, as well as theoretical knowledge of cell engager therapeutics
  • Experience managing key project deliverables for multiple projects
  • Extensive hands-on experience and knowledge in a wide range of immunological assays using cell lines and primary immune cells
  • Proficiency in assays determining immune cell function including, but not limited to, flow cytometry, ELISA, live-cell imaging, cytokine analysis, cytotoxicity assays
  • Experience with biologics is strongly preferred
  • Strong interpersonal skills and a proven ability to negotiate and collaborate within cross-functional teams
  • Excellent communication skills and ability to develop and deliver effective presentations and written/oral communications for different audiences
  • Able to work effectively in a fast-paced and deadline-driven environment
  • Strong computer skills, including GraphPad Prism, FloJo, MS Word, Excel, and PowerPoint. Use of scientific databases and applications for data management and data analysis

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