Director, DEL Informatics

Found in: beBee jobs US - 2 weeks ago

Boston, Massachusetts, United States Valo Health Full time

About Us

Valo Health is a technology company that is integrating human-centric data and AI-powered technology to accelerate the creation of life-changing drugs for more patients faster. Valo was created with the belief that the drug discovery and development process can and should be faster and less expensive, with a much higher probability of success. We are using models early to fail less often, executing clinical trials to add valuation to the company, and generating fit-for-purpose data to feed back into Valo's Opal Computational PlatformTM as we reinvent drug discovery and development from the ground up. Disease doesn't wait, so neither can we.

We are a multi-disciplinary team of experts in science, technology, and pharmaceuticals united in our mission to achieve better drugs for patients faster. Valo is committed to hiring diverse talent, prioritizing growth and development, fostering an inclusive environment, and creating opportunities to bring together a group of different experiences, backgrounds, and voices to work together. We achieve the widest-ranging impact when we leverage our broad backgrounds and perspectives to accelerate a new frontier in health. Valo seeks to become the catalyst for the pharmaceutical industry and drive the digital transformation of the industry. Are you ready to join us?

What You'll Do...

· Work as part of a multidisciplinary team to support internal and external drug discovery efforts

· Support and drive the development of the Valo DNA-Encoded Library (DEL) informatic platform, which is at the interface of DEL synthesis, selections, data analysis, and machine learning. This includes...

· Building pipelines to facilitate the tracking of BBs and oligos from DEL design and build through to the enumeration of final products

· Improving the user interface that tracks DEL selection conditions

· Writing code to calculate statistics from DEL selection datasets

· Designing/suggesting tools to increase efficiency and accuracy of DEL data analysis

· Working with the DEL team on data analysis to support internal and external programs

· Supporting DEL machine learning efforts in collaboration with data science

· Maintaining the DEL platform in collaboration with IT, engineering, and data science

· Support the multidisciplinary workflow between data science, engineering, and discovery sciences to further advance our drug discovery platform...

· Help enable platforms that intersect between wet-lab and data science to vastly improve speed and quality of DMTA cycles through machine learning

· Help to informatically bridge the gaps between wet-lab and data science


What You Bring...

· A Ph.D. in cheminformatics or a related field with over 8 yrs experience (for M.S. over 10 yrs. experience and over 15 yrs experience for a BS)

· Proficient in key programming languages and frameworks: Python, SQL, Bash, Streamlit, etc.

· Proficient with common cheminformatics applications (i.e. Spotfire, ChemAxon, RDKit, etc.)

· Proficient with cloud-based database applications (i.e. Snowflake, AWS, Oracle, etc.)

· Must have the ability to work with large data sets (millions to billions of data points)

· This individual will be making pipelines that bridge the wet-lab with informatics so they must have an understanding of wet-lab workflows, the data generated from those workflows, and relevant statistics

· This person must be independent and confident supporting novel informatic workflows. This includes making new pipelines, virtual machines, and user interfaces to facilitate the DEL workflow.

· This person needs to understand organic chemistry to the point where they can support the informatic portion of the small molecule synthesis and generate tools to look at general properties of small molecules

· This person must be able to work in a multidisciplinary environment

· Experience with DEL platforms is preferred

· Experience with data science and machine learning techniques is preferred

More on Valo

Valo Health, Inc ("Valo") is a technology company built to transform the drug discovery and development process using human-centric data and artificial intelligence-driven computation. As a digitally native company, Valo aims to fully integrate human-centric data across the entire drug development life cycle into a single unified architecture, thereby accelerating the discovery and development of life-changing drugs while simultaneously reducing costs, time, and failure rates. The company's Opal Computational PlatformTM is an integrated set of capabilities designed to transform data into valuable insights that may accelerate discoveries and enable Valo to advance a robust pipeline of programs across cardiovascular metabolic renal, oncology, and neurodegenerative disease. Founded by Flagship Pioneering and headquartered in Boston, MA, Valo also has offices in Lexington, MA, and New York. To learn more, visit

  • NIH- Funded Postdoc Position in Healthcare AI

    Found in: beBee jobs US - 1 week ago

    Boston, Massachusetts, United States CHIP Boston Childrens Hospital Full time

    CHIP, the Computational Health Informatics Program at Boston Children's Hospital, an affiliate of Harvard Medical School and a collaborating program of its Department of Biomedical Informatics, is recruiting postdoctoral fellows with an interest in advancing healthcare with artificial intelligence.Candidates should be keen on utilizing artificial...

  • Associate Director/Director, Cheminformatics

    Found in: beBee jobs US - 1 week ago

    Boston, Massachusetts, United States Matchpoint Therapeutics Full time

    Matchpoint is a biotechnology company harnessing the power of covalency to discover precision covalent medicines to transform the treatment of immune diseases and other serious illnesses. The company's proprietary Advanced Covalent Exploration (ACE) platform integrates advanced chemoproteomics, machine learning and covalent chemistry library evolution....

  • Pathology - Physician - Academics

    Found in: beBee jobs US - 1 week ago

    Boston, Massachusetts, United States Tufts Medical Center - Tufts Medicine Full time

    The Department of Pathology and Laboratory Medicine of Tufts Medical Center, Tufts Medicine, is seeking a full-time Medical Director of the Core Laboratory. The Core laboratory functions include technical, regulatory, and clinical oversight of core laboratory functions of clinical chemistry, point-of-care, laboratory information systems/informatics, mass...

  • Director, Clinical Research Informatics

    1 week ago

    Boston, United States CareerBuilder Full time

    Director, Clinical Research Informatics About the Company Esteemed community-based healthcare system Industry Hospital & Health Care Type Privately Held About the Role The Director, Clinical Research Informatics will be responsible for developing and implementing the organization's clinical research objectives in addition to establishing robust CRI programs....

  • Director of IT, Clinical Development Systems

    Found in: Jooble US O C2 - 3 days ago

    Boston, MA, United States Tandym Group Full time

    A biotechnology company in Massachusetts is currently seeking an experienced IT professional to join their team in Boston as their new Director of IT, Clinical Development Systems. Partnering with the Clinical Development and Operations leaders, the Director of IT, Clinical Development Systems will be responsible for developing and executing against a...

  • NIH- Funded Postdoc Position in Healthcare AI

    Found in: beBee S US - 2 weeks ago

    Boston, United States CHIP Boston Childrens Hospital Full time

    CHIP, the Computational Health Informatics Program at Boston Children’s Hospital, an affiliate of Harvard Medical School and a collaborating program of its Department of Biomedical Informatics, is recruiting postdoctoral fellows with an interest in advancing healthcare with artificial intelligence. Candidates should be keen on utilizing artificial...

  • Head of Cloud Development

    Found in: Jooble US O C2 - 3 days ago

    Boston, MA, United States Tandym Group Full time

    A biotechnology company in Massachusetts is currently seeking an experienced IT professional to join their team in Boston as their new Director of IT, Clinical Development Systems. Partnering with the Clinical Development and Operations leaders, the Director of IT, Clinical Development Systems will be responsible for developing and executing against a...

  • Director Biostatistics

    Found in: Jooble US O C2 - 2 weeks ago

    Boston, MA, United States Barrington James Limited Full time

    Director of Biostatistics As a Director of Biostatistics, you will assume a prominent role in leading a diverse range of projects, offering expert consultation and collaboration with professionals in epidemiology, informatics, clinical, data science, and engineering. In this role, you will further hone your analytical skills, gain exposure to various...

  • English Language Director

    Found in: Jooble US O C2 - 2 weeks ago

    Boston, MA, United States Commonwealth Care Alliance Full time

    Under the direction of, and in close collaboration with, the Vice President, Population Health & Network Quality, the Senior Director, Quality Performance and Value Based Care is responsible for leading the development and maintenance of quality performance programs, as well the development and analysis of performance measures related to value based care....

  • Global Director of Sustainability Impact Reporting

    Found in: Jooble US O C2 - 3 days ago

    Boston, MA, United States Griffith Foods Full time

    Griffith Foods Overview Griffith Foods es un fabricante global de productos alimenticios. Proporcionamos una amplia gama de componentes de sabor y textura para clientes de la industria alimentaria de todo el mundo. Nuestros productos incluyen mezclas de condimentos, mezclas secas, sistemas de recubrimiento, mezclas de masas, migas, sabores, salsas y bases...

  • Pathology - Physician - Academics

    Found in: beBee S US - 1 week ago

    Boston, United States Tufts Medical Center - Tufts Medicine Full time

    The Department of Pathology and Laboratory Medicine of Tufts Medical Center, Tufts Medicine, is seeking a full-time Medical Director of the Core Laboratory. The Core laboratory functions include technical, regulatory, and clinical oversight of core laboratory functions of clinical chemistry, point-of-care, laboratory information systems/informatics, mass...

  • Sr. Director, Quality Performance

    Found in: Jooble US O C2 - 2 weeks ago

    Boston, MA, United States Commonwealth Care Alliance Full time

    Under the direction of, and in close collaboration with, the Vice President, Population Health & Network Quality, the Senior Director, Quality Performance and Value Based Care is responsible for leading the development and maintenance of quality performance programs, as well the development and analysis of performance measures related to value based care....

  • Business Manager

    1 week ago

    Boston, United States West Headhunting Full time

    Acerca del puesto Business Manager Job brief We are looking for a Business Manager to manage the operations of the business and ensure employees meet the company's objectives. You will need strong communication abilities to maintain relations with vendors and suppliers as well as encourage employees to be at their best when performing for the company....

  • Enterprise Account Executive

    1 week ago

    Boston, United States TetraScience Full time

    Who We AreTetraScience is the Scientific Data and AI Cloud company with a mission to radically improve and extend human life. TetraScience combines the world's only open, purpose-built, and collaborative scientific data and AI cloud with deep scientific expertise across the value chain to accelerate and improve scientific outcomes. TetraScience is catalyzing...

  • Provider Partnerships

    Found in: Jooble US O C2 - 2 weeks ago

    Boston, MA, United States Commonwealth Care Alliance Inc. Full time

    Provider Partnerships & Performance Intern #24-231 Internships Why This Role is Important to Us Commonwealth Care Alliance (CCA) is thrilled once again to host its Summer Internship Program for clinical and non-clinical departments! The Internship Program is open to undergraduate and graduate students from across the country. CCA Internships are a...

  • Enterprise Account Executive

    1 week ago

    Boston, United States TetraScience Full time

    Job DescriptionJob DescriptionWho We AreTetraScience is the Scientific Data and AI Cloud company with a mission to radically improve and extend human life. TetraScience combines the world's only open, purpose-built, and collaborative scientific data and AI cloud with deep scientific expertise across the value chain to accelerate and improve scientific...

  • Director, Privacy

    Found in: Jooble US O C2 - 1 week ago

    Boston, MA, United States Commonwealth Care Alliance Full time

    Why This Role is Important to Us The Director, Privacy and Security directs and manages Commonwealth Care Alliance's (CCA) efforts to ensure compliance with laws, regulations and policies that govern information privacy and security including, but not limited to: Health Insurance Portability and Accountability Act (HIPAA), Health Information Technology...

  • MEDICAL DOSIMETRIST

    Found in: Careerbuilder One Red US C2 - 17 hours ago

    Boston, MA 02298, USA, United States Massachusetts General Hospital Full time

    The medical dosimetrist is a member of the radiation oncology team who has knowledge of the overall characteristics and clinical relevance of radiation oncology in the management of cancer or other disease processes, with special expertise in radiation therapy treatment planning. The dosimetrist provides technical information and support to radiation...

  • SOLID ORGAN TRANSPLANT CLINICAL PHARMACIST

    Found in: Careerbuilder One Red US C2 - 15 hours ago

    Boston, MA 02298, USA, United States Brigham and Women's Hospital Full time

    GENERAL SUMMARY/ OVERVIEW STATEMENTResponsible for the optimization of drug therapy by identification, resolution, and prevention of drug related problems and improving therapeutic outcomes.Responsible for providing patient care according to the laws and regulations governing pharmacists and the practice of pharmacy by the appropriate state and federal...

  • ANTINEOPLASTIC STEWARDSHIP PHARMACIST

    Found in: Careerbuilder One Red US C2 - 13 hours ago

    Boston, MA 02298, USA, United States Brigham and Women's Hospital Full time

    GENERAL SUMMARY/ OVERVIEW STATEMENTResponsible for the optimization of drug therapy by identification, resolution, and prevention of drug related problems and improving therapeutic outcomes in Oncology care.Responsible for providing patient care according to the laws and regulations governing pharmacists and the practice of pharmacy by the appropriate state...