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Bio-conjugation Scientist

3 months ago

South San Francisco, United States eTeam Full time

This is a Bio-conjugation Scientist role.

• Minimum 8 years of relevant industry experience is needed with BS/MS and 5 years with PHD.

Required:

• Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC(Size Exclusion Chromatography), SDS-PAGE, UV-Vis

• Nice to have skills: Biologics analytic experience, purification techniques.

• Must have: Bio-conjugation experience, protein biochemistry and Chemistry background.

Personality: Team player, Adheres to timeline, Communicative and collaborative.

Note: Onsite, 100% Lab based role. Possibility of extension.


Responsibilities:

This is a Bio-conjugation Scientist role with client SSF Discovery Chemistry group.

Client is currently seeking highly motivated and exceptional a Bio-conjugation Scientist for positions within the Discovery Chemistry Department located at our South San Francisco, CA site.

• The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent novel medicines by applying optimized conjugation protocols, analytical techniques, and data analysis to synthesize drug candidates and intermediates.

• Successful candidates must have excellent interpersonal, collaboration, and communication skills in a team environment.

• Additionally, it is expected that the successful candidate will learn quickly through on-the-job training to become increasingly skilled and independent in reaction setup, route design and optimization.

Education Requirement:

• Minimum qualifications include a B.S./M.S/ PHD in chemistry, biochemistry, or related field, with industrial or academic experience.

Experience and Skills Required:

• Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UV-Vis.

Specific responsibilities will include:

• Perform bioconjugations of linker-payload combinations to antibodies with Client on in-house established methods

• Selection and application of appropriate purification techniques for biologics (i.e., SEC, hydrophobic interaction chromatography, ion exchange chromatography)

• Acquisition and interpretation of analytical data such as LC/MS.