Research Associate I

3 weeks ago


Burlington, United States Harba Solutions Inc. Full time

Job Summary: We are seeking a highly motivated and detail-oriented Research Associate with expertise in high throughput sequencing to join our dynamic research team. The successful candidate will be responsible for conducting and optimizing next-generation sequencing (NGS) workflows, data analysis, and contributing to various genomics research projects. This role offers an excellent opportunity to work at the forefront of genomic research and to contribute to significant scientific discoveries.


Key Responsibilities:

  • Perform high throughput sequencing (HTS) experiments, including sample preparation, library construction, and sequencing on platforms such as Illumina, PacBio, or Oxford Nanopore.
  • Optimize and troubleshoot NGS protocols to improve efficiency, accuracy, and throughput.
  • Conduct quality control (QC) assessments on samples, libraries, and sequencing data using relevant tools and methodologies.
  • Analyze sequencing data using bioinformatics tools and pipelines, including alignment, variant calling, and data visualization.
  • Collaborate with cross-functional teams, including bioinformaticians, biologists, and computational scientists, to interpret sequencing data and integrate results into broader research objectives.
  • Maintain accurate and detailed laboratory records, including experimental protocols, data, and results.
  • Stay current with advances in high throughput sequencing technologies and bioinformatics methodologies to incorporate best practices into ongoing projects.
  • Assist in the preparation of research reports, presentations, and manuscripts for publication.
  • Contribute to the general maintenance and organization of the laboratory, including equipment calibration and ordering supplies.

Qualifications:

  • Bachelor’s degree in Molecular Biology, Genetics, Biochemistry, or a related field; Master’s degree preferred.
  • 2+ years of hands-on experience with high throughput sequencing technologies and NGS data analysis.
  • Proficiency in molecular biology techniques, including DNA/RNA extraction, PCR, and library preparation.
  • Familiarity with sequencing platforms such as Illumina, PacBio, or Oxford Nanopore.
  • Experience with bioinformatics tools and software for NGS data analysis (e.g., BWA, GATK, FastQC, R, Python).
  • Strong analytical skills and the ability to interpret complex data sets.
  • Excellent organizational skills and attention to detail.
  • Ability to work independently as well as collaboratively in a team-oriented environment.
  • Strong communication skills, both written and verbal.



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