Scientist, Medicinal Chemistry

2 weeks ago

South San Francisco, United States R2M Pharma, Inc. Full time

Job description:


R2M Pharma is a biotechnology research organization devoted to the discovery of high-quality small molecule preclinical development compounds for the treatment of unmet medical indications. We are searching for highly motivated, team-oriented scientists with strong technical skills and a track record of problem solving to join our team of professionals devoted to advancing novel treatments to unmet medical indications. 


Essential Duties and Responsibilities:


- As a scientist in medicinal chemistry, effectively drive the medicinal chemistry efforts to meet aggressive corporate timeline

- Conceive and execute novel ideas for the rapid optimization and improvement of chemical leads

- Closely follow emerging results in pharmacological and ADME assays to contribute to the optimization strategy and advancement of lead candidates

- Proactively gain competitive intelligence using available resources and incorporate this knowledge into internal drug discovery programs

- Regularly provide medicinal chemistry and project updates to a multidisciplinary drug discovery team and senior management

- Maintain a high level of productivity in the laboratory as evidenced by consistently generating high-impact compounds

- Lead and contribute to the writing of patent applications, study reports, and scientific publications


Qualifications: 


- PhD or postdoctoral training in organic or medicinal chemistry. Medicinal chemistry experience in pharmaceutical industry highly preferred but not necessary. 

- Extensive knowledge of synthetic organic chemistry and superior problem-solving skills 

- Skilled in the art and practice of modern synthetic and mechanistic organic chemistry with demonstrated experience in designing and executing multistep synthesis of complex organic molecules

- A strong track record of creative problem solving

- Competence with the use of modern spectroscopic methods applied to structure determination including 1H NMR, 13C NMR, 2D NMR, IR, and mass spectroscopy

- Experience in the use of preparative and analytical chromatographic separations

- Excellent oral and written communication skills

- Excellent teamwork skills and the ability to work efficiently and productively in a fast- paced, multi-disciplinary environment

- Competence with good laboratory practices that promote a safety-oriented professional work environment

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