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Clinical Scientist
3 months ago
Position Summary:
We are seeking a highly motivated and detail-oriented Clinical Scientist to join our team and support our ongoing clinical trials, with a particular focus on asthma exacerbations. The Clinical Scientist will play a pivotal role in the design, execution, and management of clinical trials aimed at developing breakthrough therapies in the inflammation space. This position requires a strong background in clinical research. The ideal candidate will provide scientific expertise, oversee key operational workflows, and ensure the smooth coordination of clinical activities across cross-functional teams and external partners.
Key Responsibilities:
- Clinical Trial Oversight: Provide scientific and operational support to the design, execution, and monitoring of clinical trials in the inflammation space, focusing on respiratory and inflammatory disease areas.
- Data Review & Analysis: Oversee patient data reviews, including patient profiles and medical listings, to ensure data integrity and support clinical decision-making.
- Protocol & Site Support: Serve as a point of contact for protocol inquiries from clinical sites, providing guidance on clinical procedures and addressing operational questions.
- Collaborative Teamwork: Participate in cross-functional meetings (site startup, vendor meetings, ePRO, and more) to ensure effective communication and project alignment.
- Vendor and CRO Interface: Work closely with clinical vendors (e.g., CROs, data management teams) to address clinical concerns and ensure trial quality standards are met.
- Regulatory Compliance: Ensure all clinical activities comply with regulatory and ethical guidelines, monitoring patient safety and trial integrity.
- Stakeholder Communication: Actively communicate with internal teams and external partners to keep everyone informed on clinical trial progress, emerging issues, and data interpretation.
Qualifications:
- Advanced degree (PhD, PharmD, MD, or equivalent) in life sciences, clinical research, or a related field.
- 3+ years of experience in clinical research or clinical development, preferably in the inflammation, respiratory, or immunology space.
- Strong understanding of clinical trial protocols, regulatory standards (GCP, ICH), and data monitoring practices.
- Proven ability to work collaboratively with cross-functional teams and external stakeholders (CROs, clinical sites, vendors).
- Excellent written and verbal communication skills for clear reporting and interfacing with clinical teams.
- Strong analytical skills and attention to detail.
About Upstream Bio:
Upstream Bio is a public company based in Waltham, MA. We are developing verekitug, the only known antagonist currently in development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP). We have advanced this highly potent monoclonal antibody into separate Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) and plan to initiate development in chronic obstructive pulmonary disease (COPD). Our experienced team is committed to maximizing verekitug’s unique attributes to address the substantial unmet needs for patients underserved by today’s standard of care. Learn more about us at upstreambio.com.
