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Process Development Technician

4 months ago


Conroe, United States VGXI Full time

If you are driven by innovation, fueled by scientific curiosity, and committed to making a positive impact on the global pharmaceutical community, you’ve come to the right place. We are always looking for quality-minded, team-oriented individuals who share our dedication to excellence. At VGXI, we’ve cultivated a workplace that people genuinely enjoy being a part of, and we take immense pride in the role they play in shaping our success story. We embrace a culture of quality in our products and in our people. Explore the possibilities, unlock your potential, and contribute to the future of Plasmid DNA manufacturing and precision medicine with VGXI.


SUMMARY


Conduct research scale production of plasmid DNA on an ongoing basis. Perform and document routine maintenance on PD equipment. Assist the execution and analysis of data for the purpose of fermentation and purification process development. Assist the analysis of samples from cGMP seed banking, fermentation and purification processes. Assist experiments to evaluate new technologies as designed and supervised by senior team members. Maintain a clean and organized laboratory environment.


ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.


  • Follow batch records or SOPs to conduct cell banking, fermentation and purification processes for plasmid DNA manufacture at research or GLP scale.
  • Conduct miniprep, concentration and gel analysis to in-process samples of research and cGMP productions.
  • Responsible for documentation and maintenance of PD equipment, such as: documenting new equipment and equipment changes, changing temperature charts, conducting and documenting PM for certain PD equipment, etc.
  • Execute or assist fermentation experiments designed by senior team members to optimize fermentation process.
  • Execute or assist in purification experiments designed by senior team members to optimize plasmid purification process.
  • Execute or assist in experiments designed by senior team members to evaluate new technologies.
  • Perform and record Daily and Weekly cleaning of PD area.
  • Clean and sanitize process related glassware and equipment.


EDUCATION and/or EXPERIENCE


  • Bachelor’s or Associate's degree or equivalent from college or technical school; or one to three years related experience and/or training; or equivalent combination of education and experience.