Upstream & Downstream Manufacturing Process Technician

1 month ago

Conroe, United States VGXI Full time

If you are driven by innovation, fueled by scientific curiosity, and committed to making a positive impact on the global pharmaceutical community, you’ve come to the right place. We are always looking for quality-minded, team-oriented individuals who share our dedication to excellence. At VGXI, we’ve cultivated a workplace that people genuinely enjoy being a part of, and we take immense pride in the role they play in shaping our success story. We embrace a culture of quality in our products and in our people. Explore the possibilities, unlock your potential, and contribute to the future of Plasmid DNA manufacturing and precision medicine with VGXI.


SUMMARY

Responsible for manufacturing revolutionary clinical and commercial nucleic acid-based pharmaceuticals by interfacing with manual and automated production systems and controls in cGMP manufacturing environment while maintaining areas in a state of compliance with internal quality systems. Follows standard operating procedures to operate production equipment for upstream/downstream operations. Maintains records, process, and clean room environment to comply with regulatory requirements utilizing current Good Manufacturing Practices (cGMP) and Standard Operating Procedures (SOP). Responsible for proficiency in assigned functional area: Upstream/Downstream Manufacturing. Understands and applies biological, chemical, and mechanical principles and techniques.


ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.


  • Manufacture plasmid DNA conforming to GMP guidelines and VGXI SOPs.
  • Upstream: Follow production records or SOPs and accurately document work to conduct cell banking, fermentation, and lysis processes for plasmid DNA manufacture.

or

  • Downstream: Follow production records or SOPs and accurately document work to conduct chromatography, filtration, aseptic processing, and product formulation and filling for plasmid DNA manufacture.
  • Perform work following aseptic processing guidelines as appropriate.
  • Prepare solutions required for the production process (media and buffer make-up).
  • Clean, assemble, and sterilize equipment for production by operating glass washers and autoclaves.
  • Write or Revise Standard operating procedures.
  • Install, commission and troubleshoot equipment as needed.
  • Responsible for documentation and maintenance of equipment, such as: documenting new equipment and equipment changes, conducting and documenting PM as required, ensuring proper documentation of equipment repair, etc.
  • Perform daily cleaning and sanitization of Production Areas.


EDUCATION and/or EXPERIENCE


Bachelor’s or Associate's degree or equivalent from college or technical school; or one to three years related experience and/or training; or equivalent combination of education and experience.


  • Upstream & Downstream Manufacturing Process Technician

    1 month ago

    Conroe, United States VGXI Full time

    If you are driven by innovation, fueled by scientific curiosity, and committed to making a positive impact on the global pharmaceutical community, you’ve come to the right place. We are always looking for quality-minded, team-oriented individuals who share our dedication to excellence. At VGXI, we’ve cultivated a workplace that people genuinely enjoy...

  • Process Technician

    4 weeks ago

    Conroe, United States Utex Industries Inc Full time

    LOCATION: Conroe, TX **/OBJECTIVE**: The Process Technician plays an impactful role in maintaining manufacturing process stability and contributing to the optimization of Overall Equipment Effectiveness (OEE). This position involves executing manufacturing processes, supporting the development of process improvements, and collaborating with engineering...

  • Lead Process Engineer-Hertha Metals

    2 weeks ago

    Conroe, United States Pear VC Full time

    About Hertha Metals, Inc.At Hertha Metals, our unwavering commitment is to revolutionize the heavy industry by embracing technologies that significantly decrease carbon emissions and uplift humanity. While the global steel sector plays a crucial role in providing secure and resilient infrastructure for society, it is also responsible for 10% of worldwide CO2...

  • Lead Process Engineer-Hertha Metals

    2 weeks ago

    Conroe, Texas, United States Pear VC Full time

    Lead Process Engineer About Hertha Metals, Inc. At Hertha Metals, our unwavering commitment is to revolutionize the heavy industry by embracing technologies that significantly decrease carbon emissions and uplift humanity. While the global steel sector plays a crucial role in providing secure and resilient infrastructure for society, it is also responsible...

  • Lead Process Engineer-Hertha Metals

    4 weeks ago

    Conroe, United States Pear VC Full time

    About Hertha Metals, Inc. At Hertha Metals, our unwavering commitment is to revolutionize the heavy industry by embracing technologies that significantly decrease carbon emissions and uplift humanity. While the global steel sector plays a crucial role in providing secure and resilient infrastructure for society, it is also responsible for 10% of worldwide...

  • Molding Process Technician

    4 weeks ago

    Conroe, United States STERIS - Operations Full time

    At STERIS, we help our Customers create a healthier and safer world by providing innovative healthcare and life science product and service solutions around the globe. **Position Summary**: Responsible for setting molds, starting machines and ancillary equipment to validated parameters, solve technical problems, and mentor and guide Process Technicians....

  • Lead Metallurgical Process Engineer

    3 weeks ago

    Conroe, United States Galaxy Technology Hires LLC Full time

    Our client is committed to revolutionizing heavy industry towards technologies that improve humanity by drastically cutting down carbon emissions. The global steel sector provides the backbone for modern society, delivering safe and resilient infrastructure for the world’s population, yet it contributes 10% of global CO2 emissions. Our client is building a...

  • Molding Process Technician

    4 weeks ago

    Conroe, United States STERIS - Operations Full time

    Job DescriptionJob DescriptionAt STERIS, we help our Customers create a healthier and safer world by providing innovative healthcare and life science product and service solutions around the globe.Position SummaryResponsible for setting molds, starting machines and ancillary equipment to validated parameters, solve technical problems, and mentor and guide...

  • Molding Process Technician

    2 months ago

    Conroe, United States STERIS - Operations Full time

    Job DescriptionJob DescriptionAt STERIS, we help our Customers create a healthier and safer world by providing innovative healthcare and life science product and service solutions around the globe.Position SummaryResponsible for setting molds, starting machines and ancillary equipment to validated parameters, solve technical problems, and mentor and guide...

  • Molding Process Technician

    2 weeks ago

    Conroe, United States STERIS - Operations Full time

    Job DescriptionJob DescriptionAt STERIS, we help our Customers create a healthier and safer world by providing innovative healthcare and life science product and service solutions around the globe.Position SummaryResponsible for setting molds, starting machines and ancillary equipment to validated parameters, solve technical problems, and mentor and guide...

  • Lead Metallurgical Process Engineer

    4 weeks ago

    Conroe, United States Galaxy Technology Hires LLC Full time

    Job DescriptionJob DescriptionOur client is committed to revolutionizing heavy industry towards technologies that improve humanity by drastically cutting down carbon emissions. The global steel sector provides the backbone for modern society, delivering safe and resilient infrastructure for the world's population, yet it contributes 10% of global CO2...

  • Lead Metallurgical Process Engineer

    4 weeks ago

    Conroe, United States Galaxy Technology Hires LLC Full time

    Job DescriptionJob DescriptionOur client is committed to revolutionizing heavy industry towards technologies that improve humanity by drastically cutting down carbon emissions. The global steel sector provides the backbone for modern society, delivering safe and resilient infrastructure for the world's population, yet it contributes 10% of global CO2...

  • Maintenance Technician

    6 days ago

    Conroe, United States Texas Tissue Converting Full time

    Texas Tissue Converting is a manufacturing company based in Conroe, TX (North Houston) that produces bath tissue and paper towels. We supply paper products to local communities as well as surrounding states, offering an innovative and tailor-made service for our customers in the consumer segment. With our expertise in paper converting, our products are...

  • Molding Process Technician

    6 days ago

    Conroe, United States STERIS - Operations Full time

    **Molding Process Technician**: **Location**: Conroe, TX, 77303 The Injection Molding Process Technician is responsible for set-up, operation as well as basic processing adjustments and control on plastic injection mold machines and auxiliary equipment. Duties include tool changeovers for horizontal and vertical injection molding machines in a safe,...

  • Maintenance Technician

    3 days ago

    Conroe, United States Texas Tissue Converting Full time

    Job DescriptionJob DescriptionTexas Tissue Converting is a manufacturing company based in Conroe, TX (North Houston) that produces bath tissue and paper towels. We supply paper products to local communities as well as surrounding states, offering an innovative and tailor-made service for our customers in the consumer segment. With our expertise in paper...

  • Maintenance Technician

    4 weeks ago

    Conroe, United States Texas Tissue Converting Full time

    Job DescriptionJob DescriptionTexas Tissue Converting is a manufacturing company based in Conroe, TX (North Houston) that produces bath tissue and paper towels. We supply paper products to local communities as well as surrounding states, offering an innovative and tailor-made service for our customers in the consumer segment. With our expertise in paper...

  • Maintenance Technician

    4 weeks ago

    Conroe, United States Texas Tissue Converting Full time

    Texas Tissue Converting is a manufacturing company based in Conroe, TX (North Houston) that produces bath tissue and paper towels. We supply paper products to local communities as well as surrounding states, offering an innovative and tailor-made service for our customers in the consumer segment. With our expertise in paper converting, our products are...

  • Sterile Processing Technician

    1 month ago

    Conroe, United States Ambulatory Surgery Center Full time

    River Oaks Endoscopy needs a sterile reprocessing technician to work in the scope reprocessing room. This employee would be responsible for reprocessing endoscopy scopes. Following manufacturer's instructions for use to complete testing to ensure functional operation of all endoscopy equipment in the reprocessing room. Maintains a clean and orderly central...

  • Molding Process Technician

    4 weeks ago

    Conroe, United States STERIS - Operations Full time

    Job DescriptionJob DescriptionMolding Process TechnicianLocation: Conroe, TX, 77303The Injection Molding Process Technician is responsible for set-up, operation as well as basic processing adjustments and control on plastic injection mold machines and auxiliary equipment. Duties include tool changeovers for horizontal and vertical injection molding machines...

  • Molding Process Technician

    2 months ago

    Conroe, United States STERIS - Operations Full time

    Job DescriptionJob DescriptionMolding Process TechnicianLocation: Conroe, TX, 77303The Injection Molding Process Technician is responsible for set-up, operation as well as basic processing adjustments and control on plastic injection mold machines and auxiliary equipment. Duties include tool changeovers for horizontal and vertical injection molding machines...