Senior Research Associate

3 days ago


Cambridge, United States Integrated Resources, Inc ( IRI ) Full time

Summary:

  • This position offers the opportunity to impact a growing portfolio of targeted therapies in a fast-paced and innovative research environment.
  • We are searching for a dynamic Associate Biology Scientist with experience interrogating cellular and molecular mechanisms as they relate to kinase target pathway modulation, off-target liabilities, and resistance.


What will you do?

  • Independently, develop, optimize, and proactively troubleshoot cellular screening assays.
  • Responsible for generating, processing, interpreting, and presenting data in cross functional team meetings Proactively employ cell and molecular biology techniques, including gene targeting approaches and small molecule inhibition, to dissect mechanism of action.
  • Independently design, execute and document experiments to evaluate target dependency, off target liabilities, phenotypic responses and identifying resistance mechanisms.
  • Regularly share and present data with team members.


What minimum qualifications do we require?

  • MS/BS in oncology, cellular biology, molecular biology, or related discipline with 1+ years of industry or relevant research experience is required.
  • What additional qualifications will make you a stronger candidate?
  • Experience in developing and optimizing cell-based assays in multiple platforms (for example CTG, HTRF, AlphaLISA , FC, Jess-WB, NanoBret, Nanostring).
  • Experience with different molecular and cellular biology techniques (such as Western Blot).
  • Experience with genome editing (CRISPR or si/shRNA) for engineering cell line models is a plus.
  • Familiar with tumor models and establishing PK/PD/efficacy relationships and delivering PD readouts by western blots for in vivo tumor models.
  • Experience with standard software analytical tools, xlsx, Prism, or other synergy software.
  • Strong oral and written communication skills, as well as excellent documentation and organizational skills.
  • A team player, who listens effectively, invites response and discussion.
  • Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism



  • Cambridge, United States UCB Full time

    Make your mark for patients UCB is seeking to hire a lab-based Senior Research Associate or Associate Scientist to support early research out of our Boston R&D Hub located in Cambridge MA. This scientist will have responsibility for executing assays for identification of small molecules therapeutics across UCB’s therapeutic areas of interest. You...

  • Research Associate

    3 weeks ago


    Cambridge, Massachusetts, United States Whitehead Institute for Biomedical Research Full time

    OverviewThe Whitehead Institute for Biomedical Research is a leading nonprofit research and educational institution dedicated to improving human health through biomedical science.We are seeking a highly skilled Research Associate to contribute to our laboratory research aimed at understanding the importance of non-coding genomic variation on gene expression...

  • Research Associate

    1 month ago


    Cambridge, United States Integrated Resources, Inc Full time

    Job DescriptionJob DescriptionJob Title: Research AssociateJob Location: Cambridge, MA (ONSITE)Job Duration: 6-month+ contract with potential extensionPay Range: $44.66/hr. on W2Job Description:Research Associate / Senior Research Associate, Compound Management ContractorOverview:Seeking a highly detail-oriented with very high degree of analytical thinking,...


  • Cambridge, Massachusetts, United States Truven Health Analytics Full time

    About the Opportunity:Truven Health Analytics is seeking a highly skilled Quantitative Research Associate to join our team as a Senior Research Analyst. In this role, you will work closely with clients to understand project requirements and deliverables.Key Responsibilities:Develop and analyze quantitative modelsSynthesize data from various sources and...


  • Cambridge, United States Planet Pharma Full time

    Cambridge, MAFull time, permanent role100% onsite Research Associate II/Senior Research Associate, Quality Control & Analytical DevelopmentNotes:Looking for 2 plus years CDMO experienceWill be stress testing protein assays for eventual tech transfer to CDMO.Must have experience characterizing proteins/antibodies and developing assays using techniques such as...


  • Cambridge, United States Planet Pharma Full time

    Cambridge, MAFull time, permanent role100% onsite Research Associate II/Senior Research Associate, Quality Control & Analytical DevelopmentNotes:Looking for 2 plus years CDMO experienceWill be stress testing protein assays for eventual tech transfer to CDMO.Must have experience characterizing proteins/antibodies and developing assays using techniques such as...


  • Cambridge, United States Skills Alliance Full time

    mbedded within our client, the Center for the Development of Therapeutics (CDoT)) is a highly collaborative organization of professional drug discovery scientists. Our mission is to translate cutting edge biological insights originating from the community into impactful drug discovery projects. We combine our deep expertise in drug discovery with the...


  • Cambridge, Massachusetts, United States Novartis Group Companies Full time

    About the Role:We are seeking a highly experienced professional to lead our Oncology Drug Discovery team in Cambridge, MA. As Senior Oncology Research Director, you will be responsible for progressing innovative biotherapeutics programs, focusing on antibody drug conjugates.Key Responsibilities:Leading a scientific team within Oncology Drug Discovery to...

  • Research Associate

    3 weeks ago


    Cambridge, Massachusetts, United States Whitehead Institute Full time

    Job OverviewThe Whitehead Institute is seeking a highly motivated Research Associate to join our team. This is an ideal opportunity for recent graduates who are looking to gain additional research experience before attending graduate or medical school.The successful candidate will participate in and eventually lead research projects to characterize and...


  • Cambridge, Massachusetts, United States Simcere Zaiming Full time

    About Simcere ZaimingSimcere Zaiming is expanding its North American presence with a dynamic drug discovery team based in Cambridge, Massachusetts. As we continue to grow and advance our research capabilities, we are on the lookout for innovative and driven individuals to enhance our preclinical research division.Job Summary:We are seeking a highly skilled...


  • Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full time

    Job Title: Senior Research Scientist for Synthetic BiologyLocation: Massachusetts Institute of TechnologySalary: $60,000 - $80,000 per yearAbout the Job:We are seeking a highly skilled and motivated Postdoctoral Associate to join our research team at MIT. As a Senior Research Scientist for Synthetic Biology, you will work closely with Professor Domitilla Del...


  • Cambridge, United States Joulé Full time

    Joulé is seeking a highly skilled Senior Genomics Researcher to join our team in Cambridge, MA. As a key member of our team, you will be responsible for participating in sample collection of murine and human tissues.We are looking for a talented individual with expertise in genomics research and laboratory procedures. Your primary role will be to follow...


  • Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full time

    Company OverviewMIT's Center for Transportation & Logistics (CTL) is a leading research institution dedicated to advancing the field of supply chain management.Job SummaryWe are seeking a highly motivated and skilled Postdoctoral Associate to join our team as a Senior Supply Chain Research Fellow. In this role, you will have the opportunity to work on...


  • Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full time

    Job OverviewThe Massachusetts Institute of Technology is seeking a highly skilled Postdoctoral Associate to join the Space Enabled Group in the Program in Media Arts and Sciences. This one-year appointment offers an exciting opportunity to contribute to cutting-edge research supporting projects that apply to the Environment-Vulnerability-Decision-Technology...


  • Cambridge, United States Harvard University Full time

    Location field must contain 'city, state' or a zip code to perform a radius search (e.g., Denver, CO or 46122). City and state must be separated by a comma followed by a space (e.g., Houston, TX). Harvard University Senior Director of Research Administration Cambridge, Massachusetts Apply Now 66904BRAuto req ID:66904BRJob Code:F1360M Research Admin Mgt VI...


  • Cambridge, Massachusetts, United States Catalytic Data Science Full time

    About the RoleWe are seeking a highly motivated Senior Bioinformatics Scientist to join our team at Catalytic Data Science. This is an exciting opportunity for a bioinformatician with experience in next-generation sequencing, systems biology, and/or multi-omics to contribute to building a digital workspace that has a direct impact on human health,...


  • Cambridge, Massachusetts, United States Mindlance Full time

    Job Title: Senior Research ScientistEstimated Annual Salary: $85,000 - $110,000 based on location and experience.About the RoleWe are seeking a highly skilled Senior Scientist to join our team at Mindlance in Cambridge, MA. As a key member of our research team, you will be responsible for running in vitro primary cell culture in 96-well plate format,...


  • Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full time

    We are seeking a highly skilled Senior Mechanical Engineer Researcher to join our team at the Massachusetts Institute of Technology.About the RoleThis is a unique opportunity to support research on clinically-relevant solutions to gastrointestinal drug delivery systems. As a Senior Mechanical Engineer Researcher, you will design and develop drug delivery...


  • Cambridge, Massachusetts, United States Alphanumeric Systems Inc. Full time

    Alphanumeric Systems Inc. is seeking a highly skilled Senior Research Chemist to join their team in Cambridge, MA.About the RoleWe are looking for a talented individual with a strong background in analytical chemistry and experience working with high-throughput screening technologies. The successful candidate will be responsible for executing routine...


  • Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full time

    About the Opportunity\We are seeking a highly motivated Postdoctoral Associate to join the LIFT Lab at the Massachusetts Institute of Technology. As a key member of our team, you will contribute to research projects and teaching activities related to low-income firms transformation.\Key Responsibilities\Assist in conducting independent research under the...