Immuno-Oncology - Senior Scientist

4 weeks ago

South San Francisco, United States Amgen Full time

HOW MIGHT YOU DEFY IMAGINATION?

You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Immuno-Oncology - Senior Scientist

Live

What you will do

Let’s do this. Let’s change the world. In this vital role you will lead discovery research projects in the Immuno-Oncology group and investigate mechanisms of immune regulation in cancer, with a focus on myeloid and stromal cell biology. The candidate will work to discover and validate new therapeutic targets using cutting-edge technologies, such as single cell and spatial transcriptomics, 3-dimensional organoid cultures, and/or in vitro and in vivo gain/loss-of-function screens. This position will be an integral component of a dynamic research team collaborating across multiple Amgen sites and functional areas, including Therapeutic Discovery and Medical Sciences.

Key Responsibilities

  • Lead immuno-oncology discovery research projects (as a Biology Lead in Project Teams) and develop novel immuno-oncology therapeutics.

  • Independently design experimental strategy, execute laboratory-based experiments, analyze data, and communicate and present in team and departmental meetings.

  • Apply innovative technologies and approaches to identify and validate novel therapeutic targets.

  • Publish experimental findings in top-tier journals and present at leading scientific conferences.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

  • Doctorate degree and immunology or oncology experience OR

  • Master’s degree and 3 years of immunology or oncology experience OR

  • Bachelor’s degree and 5 years of immunology or oncology experience

Preferred Qualifications:

  • Doctorate degree with postdoctoral training and research experience in the fields of immunology and/ or oncology.

  • Demonstrated track record of independent critical thinking and scientific achievement in the areas of immunology or oncology, as demonstrated by high impact publications and/or patents.

  • Demonstrate independence and creative thinking in leading drug-discovery projects, designing in vitro and in vivo biological studies, as well as ability to troubleshoot and solve complex problems.

  • Demonstrate technical expertise in the following areas: multi-color flow cytometry, primary immune cell culture, and genetic engineering (molecular biology).

  • Hands-on experience with mRNA-transfection-based assays and 3D complex cell-based assays for co-culture of tumor cells, T cells and myeloid cells is highly preferred.

  • Direct experience with various preclinical animal models of cancer, including design of efficacy/PD (pharmacodynamics) endpoints is a plus.

  • Strong interpersonal communication skills, both verbal and written.

  • Effectively prioritize and implement next steps with efficient time management.

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans and bi-annual company-wide shutdowns

  • Flexible work models, including remote work arrangements, where possible

Apply now for a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.com

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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