Senior Manager, IT

1 month ago

Boston, United States Entrada Therapeutics Full time

The Organization

What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible.

Our Endosomal Escape Vehicle (EEV™)-therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RNA-, antibody- and enzyme-based programs for the potential treatment of neuromuscular, ocular, metabolic and immunological diseases, among others.

Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45 and 50 skipping amenable. We have also partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.

We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.

The Perfect Addition to Our Team

You are a motivated, resourceful, and enthusiastic Senior Manager, IT. You enjoy having oversight and direct involvement in the organizations systems that support growing Entrada Therapeutics many business functions. You enjoy analyzing complex issues to develop relevant and realistic plans against gathered business requirements focused on driving project/program portfolios/recommendations. If you can lead these activities with minimal supervision, yet thrive in a collaborative setting, this role is for you. At Entrada, you will not be siloed, but rather expected to interact with key business stakeholders at ALL levels within the organization. As such, you must have good conflict management and negotiation skills. Your ability and desire to thrive in a nimble, fast-paced, results-driven environment will set you up for success.

The Opportunity

Entrada Therapeutics is searching for a motivated and resourceful, Senior Manager, IT to initiate, drive, manage and deliver complex IT projects, ensuring they are delivered on time, within scope, and within budget. The successful candidate will have a strong technical background in IT, as well as exceptional leadership, organizational, and communication skills. Reporting to the Head of IT, Sr Manager of IT plans, leads, implements, maintains systems and related control environment. This includes gathering and documenting business requirements for solutioning, project leadership, performing administrative and management tasks to maintain application operation, oversite for new systems (end to end management), developing reports, supporting ancillary software, and maintaining system compliance, security, and performance. The Senior Manager of IT will also be responsible for overseeing the technology infrastructure and systems that support our R&D and lab operations. This position will be the liaison for system users and 3rd party vendor services contacts.

Responsibilities

IT Infrastructure and Systems Management

Oversees the design, implementation, and maintenance of IT infrastructure, including servers, storage, networking, and data centers. Ensures the reliability, availability, and performance of all IT systems, identify areas for improvement, and lead initiatives to enhance efficiency and scalability. Collaborates with vendors and service providers to deliver high-quality IT solutions and support (electronic lab notebooks – ELN, specialized R&D applications and more). Implements and enforces IT policies and procedures to ensure data security, disaster recovery, and business continuity.

Support R&D/Lab Systems

Acts as the primary IT liaison for research and development teams, understanding their unique requirements and challenges. Develops and implements IT strategies to support the lifecycle of R&D projects, from early-stage research to commercialization. Ensures that IT systems and applications used comply with regulatory standards (e.g., GxP, 21 CFR Part 11). Ensure that all IT activities comply with relevant regulations, including data protection laws and industry-specific standards. Conduct regular risk assessments and audits to identify potential vulnerabilities and implement mitigation strategies.

Business Analysis & Project Management

Gains full understanding of business needs working with key stakeholders to document and gather IT requirements for complete clarity and signoff. Based on business requirements, reviews potential solutioning alternatives. Presents solution(s) pros/cons, budget, ROI, and recommended solution to business leadership for approval. Ensures IT control framework is designed appropriately and compliant with various regulatory standards but not limited to HIPAA and GDPR. Monitors software requirements, determines application utilization, and recommends upgrades/enhancements as needed.  Enhances existing Cyber security program in place and prioritizes regular reporting. Manages, leads, and delivers large-scale IT projects, including planning, schedule, resources/conflicts, execution, risk mitigation, monitoring, and completion against budget, time and scope. Coordinates, leads, and reports out overall IT project portfolio and governance to business leadership on a regular cadence.

Others

Partners with business units and managed service provider (MSP) to understand current systems and business processes, provides best practice guidance and informs on latest features and functionalities.  Provides training and support to end-users of IT solutions. Serves as a strategic partner to other departments, including R&D, Finance, HR, and Operations, to align IT initiatives with business objectives. Manages IT budgets, forecasts, and resource allocation to ensure cost-effective solutions and investments. Stays abreast of emerging technologies and industry trends to recommend innovative solutions that drive business success.

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

Humanity - We genuinely care about patients and about one another. Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients. Creativity - We are creative problem solvers. Collaboration - We are more than the sum of our parts. Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

BS (MS preferred) in Computer Science, Information Systems, or related technical field and equivalent experience required. 7+ years of experience in IT management, with a focus on supporting R&D and laboratory systems in the biotech or pharmaceutical industry. Self-starter with can do attitude, customed to growth-oriented company and brings service first mindset. Strong technical background in IT and an understanding of software development lifecycle (SDLC). Proven record of defining need, requirements, and delivery of complex IT projects on time, within scope and budget across diverse functional business areas. Excellent leadership, organizational, and communication skills. Ability to manage and resolve project risks, conflicts, and issues in a timely and effective manner. Strong experience with project management tools, such as Microsoft Project, Smartsheet, Planner etc. Strong expertise in project management related to the requirements gathering, selection, installation, and management of enterprise application software systems (SaaS/Cloud likely to remain preferred model over time). Disciplined in operation of Windows-based PC’s, some Apple OS and solid familiarity with networked SaaS/Cloud based application environments. Fast paced, high growth office environment handling multiple demands. Must be able to exercise and deliver appropriate judgment as necessary. Flexible and willing to learn new systems and processes outside of comfort zone. (R&D, QA, Clinical, Infrastructure, etc.) Basic application/web/database programming is a plus but not required. PMP/other PM certification a plus.

The Perks

By becoming a team member here at Entrada, you’ll have access to competitive health, dental, and vision coverage, as well as life insurance, and short term and long-term disability insurance. We value work life balance, you'll benefit from discretionary time off, paternity leave, and an excellent 401(k) package. We also offer a generous transportation stipend to commute as you wish. Our location in the vibrant and growing Seaport District is close to all the best that the city of Boston has to offer.

Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.

Third Party Staffing Agencies

Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.

Privacy Statement

Entrada Therapeutics, Inc. (the “Entrada,” “we,” “us,” or “our”) respects your privacy and we want you to be familiar with how we collect, use, share, or otherwise process, your Personal Information. Please reference our privacy statement here to understand how and when your data is being used.

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