See more Collapse

Scientist I

1 month ago

Cambridge, United States UCB Full time

 

Make your mark for patients

 


UCB's Gene Therapy Vector Core team is seeking a Scientist I - Bioreactor & NGS to join a group focused on AAV upstream process development. The candidate will work across functional teams and will be responsible for bioreactor operations for research grade AAV production to support gene therapy platform development activities; including capsid engineering platform.   This is an onsite position and will be based out of our Bedford, MA location, 

 

NOTE:   We are interested in every qualified candidate who is eligible to work in the United States. However, we are not able to sponsor visas at any point for this role.   This includes taking over sponsorship for an existing Visa.

 

Major Responsibilities:

  • Production of AAV vectors using batch or perfumion mode in bioreactors up to 50L
  • Characterization of packaged AAV genome by next generation sequencing (NGS)
  • Support gene therapy platform development activities by applying upstream expertise
  • Good practices of data record keeping
  • Collaborate with the vector biology and downstream process development teams
  • Ability to function independently and cross functionally across various UCB teams (data scientists, cell biologists, , disease area experts, etc)

 

Minimum Requirements:

  • BS degree in Biology, Biomanufacturing or related field with 8 years of experience - OR - MS degree with 6 years of experience - OR -  PhD or Post Doc with relevant academic research experience
  • Hands-on AAV experience in industry and/or academia
  • Demonstrated past experience of either one of the following skills:
    • Upstream unit operation mastery at various scales with biologics or for viral gene therapy applications.
    • Next generation sequencing experience for characterization of libraries
  • Good communication skills with demonstrated ability to work across disciplines

 

Additional Preferred Experience/Skills:

  • MS with Biochemical Engineering or Biomanufacturing degree with direct AAV production experience in bioreactors
  • 3+ years of experience with process development of AAV vectors
  • 3+ years of hands on experience with NGS library preparation, PacBio data acquisition, analysis and QC
  • At least 1 year experience in drug discovery in a pre-clinical setting

 

Compensation Range:

       $96,480 to $126,630

 

If you are interested to learn more about R&D within UCB, please find more information here R&D at UCB.

 

RANDATUCB


 

Are you ready to âgo beyondâ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you 

 

About us 
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 9,000 people in all four corners of the globe, inspired by patients and driven by science. 

 

Why work with us? 
At UCB, we donât just complete tasks, we create value. We arenât afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We âgo beyondâ to create value for our patients, and always with a human focus, whether thatâs on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential. 

 

As an Equal Opportunity Employer, we are open to all talent, and adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. 
 
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on US-Reasonable_Accommodation@ucb.com for application to US based roles. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.

We have other current jobs related to this field that you can find below

  • Scientist I, Bioinformatics

    3 weeks ago

    Cambridge, United States Sarepta Therapeutics Full time

    The Scientist I, Bioinformatics works closely with several groups within Sarepta’s Research and Development department. The Scientist I, Bioinformatics is part of the Genomics and Data Sciences team and plays a critical role in supporting Discovery Biology to advance our portfolio of RNA, gene therapy, and CRISPR-based gene editing therapies to treat...

  • Scientist I

    1 week ago

    Cambridge, United States Bayer Full time

    **At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where 'Health for all Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our...

  • Scientist I

    4 weeks ago

    Cambridge, Massachusetts, United States UCB Full time

    Make your mark for patients UCB's Gene Therapy Vector Core team is seeking a Scientist I - Bioreactor & NGS to join a group focused on AAV upstream process development. The candidate will work across functional teams and will be responsible for bioreactor operations for research grade AAV production to support gene therapy platform development activities;...

  • Principal Scientist I

    1 week ago

    Cambridge, United States Novartis Full time

    **Summary**: **About the Role**: **Key Responsibilities**: - Develop in vivo CDX, PDX, and syngeneic models to evaluate anti-tumor activity, PK/PD relationships, relevant biomarkers, and key translational questions. - Manage associate-level scientists. - Collaborate with cross-functional project teams. - Critically analyze and present results within a...

  • Scientist I

    4 weeks ago

    Cambridge, Massachusetts, United States UCB Full time

    Make your mark for patients UCB's Gene Therapy Vector Core team is seeking a Scientist I - Bioreactor & NGS to join a group focused on AAV upstream process development. The candidate will work across functional teams and will be responsible for bioreactor operations for research grade AAV production to support gene therapy platform development activities;...

  • Principal Scientist I, Drug Discovery

    3 weeks ago

    Cambridge, United States Novartis Full time

    **Summary**: Internal Job Title: Principal Scientist I Role Location: Cambridge, MA, onsite About the role: We are seeking a motivated scientist with expertise in nephrology to join a vibrant research team focused on finding new transformative therapies for people living with renal disease. In this role, you will be responsible for driving research...

  • Data Scientist I, Research Sciences

    4 weeks ago

    Cambridge, United States Sarepta Therapeutics Full time

    The Data Scientist, Research Sciences role at Sarepta is an exciting opportunity for someone with strong data science and analytical skills who wants to see their work directly impacting patient care. In this hands-on role, the data scientist will research and develop advanced analytical methods to utilize internal and external chemistry and biological data...

  • Scientist I/II

    4 weeks ago

    Cambridge, Massachusetts, United States UCB Full time

    Make your mark for patients We are currently seeking a highly skilled and motivated Scientist I/II with expertise in molecular and cellular biology to join our Discovery Biology team. The candidate will be expected to design, execute and analyze in vivo experiments to validate gene therapy targets for the treatment of genetic diseases. This is a unique...

  • Scientist I/II

    4 weeks ago

    Cambridge, Massachusetts, United States UCB Full time

    Make your mark for patients We are currently seeking a highly skilled and motivated Scientist I/II with expertise in molecular and cellular biology to join our Discovery Biology team. The candidate will be expected to design, execute and analyze in vivo experiments to validate gene therapy targets for the treatment of genetic diseases. This is a unique...

  • Research Scientist I, Infectious Disease Monitoring

    4 weeks ago

    Cambridge, United States MIT Full time

    Job Description RESEARCH SCIENTIST I, INFECTIOUS DISEASE MONITORING , Media Lab, to join Professor Kevin Esvelt and the research group, who launched the Nucleic Acid Observatory (NAO) project to pioneer reliable, pathogen-agnostic early warning of future pandemics through untargeted metagenomic sequencing. Responsibilities include co-leading the...

  • Research Scientist I, Infectious Disease Monitoring

    2 weeks ago

    Cambridge, Massachusetts, United States MIT Full time

    Job Description RESEARCH SCIENTIST I, INFECTIOUS DISEASE MONITORING , Media Lab, to join Professor Kevin Esvelt and the research group, who launched the Nucleic Acid Observatory (NAO) project to pioneer reliable, pathogen-agnostic early warning of future pandemics through untargeted metagenomic sequencing. Responsibilities include co-leading the wet-lab...

  • Scientist I, Analytical Development of Small Molecule Pharmaceuticals

    4 weeks ago

    Cambridge, United States Biogen Full time

    Job DescriptionJob DescriptionJob DescriptionAbout This RoleBiogen is seeking a qualified candidate to fill a Scientist I position within its Analytical Development organization. This individual will be an analytical scientist responsible for managing advanced operations and analyses in a development (non-GMP) laboratory environment to support a fast-paced...

  • Sr. Scientist I, Precision Medicine, Neuroscience Biomarkers

    4 weeks ago

    Cambridge, United States AbbVie, Inc Full time

    Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services...

  • Clinical Scientist

    4 weeks ago

    Cambridge, United States Intellia Therapeutics Full time

    Why Join Intellia?Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to...

  • Senior Scientist, Protein Engineering

    3 weeks ago

    Cambridge, United States Repertoire Immune Medicines Full time

    Job DescriptionJob DescriptionSenior Scientist, Protein Engineering and Molecular SciencesCompany Overview Repertoire Immune Medicines is a biotechnology company working to unlock and direct the remarkable power of the human immune system to treat cancer, autoimmune disease and infectious disease. The company was founded by Flagship Pioneering on the belief...

  • Senior Scientist, Protein Engineering

    4 weeks ago

    Cambridge, United States Repertoire Immune Medicines Full time

    Job DescriptionJob DescriptionSenior Scientist, Protein Engineering and Molecular SciencesCompany Overview Repertoire Immune Medicines is a biotechnology company working to unlock and direct the remarkable power of the human immune system to treat cancer, autoimmune disease and infectious disease. The company was founded by Flagship Pioneering on the belief...

  • Research Scientist

    3 weeks ago

    Cambridge, United States Schlumberger Full time

    **Nuclear Research Scientist for the Energy Transition** **Location**: Schlumberger-Doll Research (SDR), Cambridge MA, United States **Status**:Full Time / Immediate **Job description**: Schlumberger-Doll Research (SDR) seeks a nuclear physicist with a passion for modeling to drive the Energy Transition. Nuclear measurements are among the most important...

  • Principal Scientist, Immunopeptidomics

    1 week ago

    Cambridge, United States Johnson & Johnson Full time

    Johnson and Johnson is recruiting for a **Principal Scientist, Immunopeptidomics & Proteomics **for our site located in Cambridge, MA. **Primary responsibilities**: - Manage a team of wet lab scientists enabling proteomic insights across a wide variety of programs and therapeutic modalities. - Plan, oversee and perform wet lab proteomic activities for...

  • Clinical-Scientific - Bench Scientist

    4 weeks ago

    Cambridge, United States Pioneer Data Systems Full time

    Position Details: Our client, a world-leading Pharmaceutical Company in Cambridge, MA is currently looking for a Associate Scientist I to join their expanding team. Job Title: Associate Scientist I / Molecular Biology Duration: 18 months contract, extendable up to 36 months Location: Cambridge, MA Note: The client has the ...

  • Principal Scientist, Protein Production

    3 weeks ago

    Cambridge, United States Repertoire Immune Medicines Full time

    Job DescriptionJob DescriptionPrincipal Scientist, Protein Production and Process DevelopmentCompany OverviewRepertoire Immune Medicines is a biotechnology company working to unlock and direct the remarkable power of the human immune system to treat cancer, autoimmune disease and infectious disease. The company was founded by Flagship Pioneering on the...