Senior Research Associate

1 month ago


San Diego, United States Tr1X Full time
  • The company develops cellular therapies with the potential to cure disease by inducing immune tolerance and restoring homeostasis.
  • More information can be found at Description:The Senior Research Associate, Discovery will work with Tr1X's Research and Development team to design and execute in vitro and in vivo studies to characterize candidate cellular therapy products to support pipeline program advancement.
  • The successful candidate will have technical expertise in the design, execution, and data analysis of immunological techniques including flow cytometry, ELISA, MSD, and similar methods.
  • Evaluate - various protocols in support of process development activities.
  • You have:A Bachelor's degree in a relevant scientific discipline and 5+ years of experience or an MS with 2+ years of experience in immunology, cell biology or related discipline including at least 2 years working with primary human cellsExperience with cell culture for primary human cells, preferably T cells and/or Tregs.
  • Experience with T-cell characterization methods (flow cytometry (multiparametric and ICS), cell-based assays (proliferation, cytotoxicity), ELISA, multiplex cytokine assays,purification using MACS system, etc
  • Experience in data analysis using Graphpad Prism, Excel, and flow cytometry analysis software (e.g. FlowJo).
  • Experience with transduction of primary T-cells with retroviral or lentiviral vectors and/or AAV.Previous cell therapy experience.


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