Sr. Scientist I, Biology
2 weeks ago
Job Title: Sr. Scientist, Biology
Location: San Diego
NH: R6
Background
RayzeBio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio will operate as a standalone entity within the BMS organization, maintaining its biotech culture with the opportunity to leverage the best-in-class oncology capabilities of BMS. RayzeBio is developing innovative drugs against targets of solid tumors. The lead asset, RYZ101, is in Phase 3 testing for patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs), as well as earlier stage testing for patients with small cell lung cancer (SCLC). Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals.
Job Description
The role offers an opportunity to advance a pipeline of novel Radiopharmaceutical therapies from target selection through candidate nomination. The ideal candidate will have excellent communication and presentation skills and will be a highly motivated biologist with a broad technical skill set to support design and execution of experiments in a drug discovery setting. The role will have an opportunity to work on multiple projects ranging from target selection through candidate nomination stages and can be expected to lead early-stage projects in an interdisciplinary setting. The role is technical and will need a person who enjoys leading from the bench with strong experimental and data analysis skills and a comfort level in working under tight timelines. The role requires an ability and willingness to work with radioactive isotopes.
Job Responsibilities
Essential duties and responsibilities include the following. Other duties may be assigned.
• Conceptualize and execute in vitro assays which contribute to answering key biological questions on project and support the screening, characterization, and lead-identification of novel RPT agents.
• Utilize a deep understanding of cancer biology and oncology drug development to support the target selection and initiation of new TRP projects.
• Work in close collaboration with interdisciplinary team members to provide needed biology support to guide programs through lead identification/optimization phases.
• Support the overall biology screening and evaluation plan, work closely with chemists, DMPK, imaging and in vivo teams to ensure implementation of screening funnel and appropriate prioritization of experiments.
• Work under the guidance of clinical, translational leads to help implement the translational biology plan to support the clinical development strategy.
• Help generate, review technical reports in support of regulatory submissions and support the publication/presentation plans with active contributions.
• Identify external partners, KOLs, outside expertise that will help advance the pipeline.
• Supervise the work of junior scientists and ensure experimental rigor and high quality.
Education and Experience
• PhD in cancer biology, cell biology, pharmacology, or a related field and a deep understanding of cancer biology and experience working in oncology drug development is ideal. Exceptional BS/MS candidates with strong track record of scientific accomplishments in industrial settings will also be considered.
• PhD 2 + years or BS with 7+ years of experience in pharmaceutical/biotech R&D environments demonstrating successful accomplishments and progressive leadership and broadening responsibilities.
• Experience in working on targeted cancer therapy modalities such as RPTs, ADCs, PDCs is highly desirable.
Skills and Qualifications
• Expertise with invitro, cell-based assay development and optimization and proficiency with Cell culture, molecular biology techniques, ELISA, flow-cytometry, western blot, qPCR, single-cell cloning, immunohistochemistry and related protocols.
• Ability to effectively partner with chemistry/DMPK, imaging and in vivo teams and ability to effectively interpret data and plan experiments accordingly.
• Strong technical problem-solving skills and a basic familiarity with ADME/PK concepts, drug design and the use of appropriate in vivo oncology models is critical.
• Excellent written and oral communication and presentation skills and ability to work in a fast-paced, dynamic, and collaborative environment.
• Ability to work with radioisotopes with strict adherence to radiation safety protocols.
• Demonstrated ability to supervise and effectively guide the work of junior scientists and demonstrated ability of productivity in an industrial drug discovery setting.
-
Sr. Scientist I, Biology
2 weeks ago
San Diego, United States RayzeBio Full timeJob Title: Sr. Scientist, BiologyLocation: San DiegoNH: R6BackgroundRayzeBio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of targeted...
-
Sr. Scientist I
2 weeks ago
San Diego, United States RayzeBio Full timeJob Title: Sr. Scientist, BiologyLocation: San DiegoNH#: 88BackgroundRayzeBio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of targeted...
-
Sr. Scientist I
2 weeks ago
San Diego, United States RayzeBio Full timeJob Title: Sr. Scientist, BiologyLocation: San DiegoNH#: 88BackgroundRayzeBio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of targeted...
-
Sr. Associate Scientist, Biology
2 weeks ago
San Diego, United States RayzeBio Full timeJob Title: Sr. Associate Scientist I or II, BiologyLocation: San DiegoBackgroundRayzeBio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of...
-
Sr. Associate Scientist, Biology
3 weeks ago
San Diego, United States RayzeBio Full timeJob Title: Sr. Associate Scientist I or II, BiologyLocation: San DiegoBackgroundRayzeBio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of...
-
Sr. Associate Scientist, Biology
5 days ago
San Diego, United States RayzeBio Full timeJob Title: Sr. Associate Scientist I or II, BiologyLocation: San DiegoBackgroundRayzeBio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of...
-
Sr. Scientist, Antibody Development
1 month ago
San Diego, California, United States Aviva Systems Biology Full timeAviva Systems Biology is a fast paced, mid stage life sciences research tools company located in San Diego, CA. We commercialize life science tools and reagents for research, drug discovery, and diagnostics.Location: San Diego, CA How will you make an impact? As part of a great team, our Sr. Scientist will have responsibility for the development of research...
-
Sr. Scientist, Antibody Development
2 weeks ago
San Diego, United States Aviva Systems Biology Full timeAviva Systems Biology is a fast paced, mid stage life sciences research tools company located in San Diego, CA. We commercialize life science tools and reagents for research, drug discovery, and diagnostics.Location: San Diego, CAHow will you make an impact?As part of a great team, our Antibody Development Sr. Scientist will have responsibility for the...
-
Sr. Scientist, Antibody Development
3 weeks ago
San Diego, United States Aviva Systems Biology Full timeAviva Systems Biology is a fast paced, mid stage life sciences research tools company located in San Diego, CA. We commercialize life science tools and reagents for research, drug discovery, and diagnostics.Location: San Diego, CAHow will you make an impact?As part of a great team, our Antibody Development Sr. Scientist will have responsibility for the...
-
Sr. Scientist, Antibody Development
2 days ago
San Diego, United States Aviva Systems Biology Full timeAviva Systems Biology is a fast paced, mid stage life sciences research tools company located in San Diego, CA. We commercialize life science tools and reagents for research, drug discovery, and diagnostics.Location: San Diego, CAHow will you make an impact?As part of a great team, our Antibody Development Sr. Scientist will have responsibility for the...
-
Sr. Scientist, Translational Biology
1 month ago
San Diego, United States Zentalis Full timeJob DescriptionJob DescriptionSalary: $125-148kJOB SUMMARY: Responsible for leading research on translational projects focused on small molecule drug combinations and understanding MoA. Generate robust datasets that will have a direct impact on our oncology drug discovery process and drug pipeline.ESSENTIAL DUTIES AND RESPONSIBILITIES:Design, conduct, and...
-
Sr. Scientist, Translational Biology
4 weeks ago
San Diego, United States Zentalis Full timeJob DescriptionJob DescriptionSalary: $125-148kJOB SUMMARY: Responsible for leading research on translational projects focused on small molecule drug combinations and understanding MoA. Generate robust datasets that will have a direct impact on our oncology drug discovery process and drug pipeline.ESSENTIAL DUTIES AND RESPONSIBILITIES:Design, conduct, and...
-
Scientist/Sr. Scientist, Development
4 weeks ago
South San Francisco, United States Talentry Full timeJob DescriptionScientist/Sr. Scientist, Development (Preclinical)South San FranciscoDirect Hire (120-170k)Talentry is looking for a skilled Scientist II or Sr. Scientist for a preclinical research role researching retinal diseases. The right scientist will collaborate across divisions, drive programs and projects, and help develop strategies, design...
-
Principal Scientist, Biology
2 weeks ago
San Diego, United States RayzeBio Full timeJob Title: Principal Scientist, BiologyLocation: San DiegoNH: R6BackgroundRayzeBio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of targeted...
-
Principal Scientist, Biology
2 weeks ago
San Diego, United States RayzeBio Full timeJob Title: Principal Scientist, BiologyLocation: San DiegoNH: R6BackgroundRayzeBio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of targeted...
-
Sr. Scientist, Phage Display
4 weeks ago
San Diego, United States Proven Recruiting Full timeSr. Scientist, Phage Display Seeking a Scientist with a go-getter attitude who can bring antibody design and molecular biology knowledge to the table, and in return they're offering opportunities to grow in an exciting, fast-paced start up environment. Ample opportunity for growth and skill development. What you'll do: Participate in all aspects of...
-
Scientist I/II
5 days ago
San Diego, United States Tr1X Full timeJob DescriptionJob DescriptionTr1X ("Trix") is a biotechnology company focused on engineering cures for autoimmune and inflammatory diseases. The company develops cellular therapies with the potential to cure disease by inducing immune tolerance and restoring homeostasis.Tr1X has a state-of-the-art technology platform that allows for the scalable generation...
-
Principal Scientist, Biology
3 days ago
San Diego, CA, United States RayzeBio Full timeJob Title: Principal Scientist, Biology Location: San Diego NH: R6 Background RayzeBio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of...
-
Sr./Principal Scientist, Translational Genetics
2 weeks ago
San Diego, United States BioPhase Full timeSr. or Principal Scientist, Translational Genetics The ideal candidate will apply their background and experience in genetics, molecular biology and disease pathophysiology towards both identifying novel therapeutic targets and formulating mechanistic hypotheses that can be evaluated experimentally.Responsibilities:The Scientist will leverage extensive human...
-
Sr./Principal Scientist, Translational Genetics
3 weeks ago
San Diego, United States BioPhase Full timeSr. or Principal Scientist, Translational Genetics The ideal candidate will apply their background and experience in genetics, molecular biology and disease pathophysiology towards both identifying novel therapeutic targets and formulating mechanistic hypotheses that can be evaluated experimentally.Responsibilities:The Scientist will leverage extensive human...