Associate Director, Bioanalysis

5 months ago

San Diego, United States WuXi AppTec Full time

Overview

HD Biosciences Inc.  a WuXi AppTec company, offers biology-focused preclinical drug discovery services to biotech and pharmaceuticals. We offer our clients comprehensive service platforms around target validation, plate-based pharmacology, hit identification and lead discovery, in vivo pharmacology, as well as other research and development services.

Responsibilities

Job Summary:

We are seeking a highly motivated and skilled Associate Director (AD) to lead our fast-growing bioanalysis platform. The AD will lead a team to achieve long-term research and business goals in a CRO setting. The position will independently design, execute, trouble shoot and deliver the projects with LCMS, including small molecules and biologics, as well as lipidomics, glycomics and proteomics.

Essential Job Functions:

Provides overall scientific and operational support for bioanalysis group. Actively contributes and applies expertise and knowledge to collaborations with partners in the design and execution of related studies Works with business management and development team for sponsor engagement and project proposal preparation. Leads multiple ongoing projects to meet expected timelines. Responsible for new capability implementation and team building. Contributes to the overall operations and to the achievement of departmental goals Communicates with clients for designing, analysis, reporting and recording activities. Performs job specific tasks in compliance with applicable Regulations, International Standards, WuXi AppTec Policies and Standard Operating Procedures. Hands-on bench work when necessary.

Qualifications

Job Requirements:

Experience / Education

PhD 5+ years of experience in Proteomics, Mass Spectrometry, and/or related field. Industry experience from CRO, biotech, and pharmaceutical is a plus; strong scientific knowledge and technical skills in the bioanalytic field, is desired. Work on Holidays and weekends when necessary Expert level skills in the following areas are required:Solid understanding of qualitative and quantitative LCMS workflows in small molecule, lipidomics, glycomics and proteomics with associated sample preparation techniquesSolid competency in a broad range of LCMS instrumentation such as QQQ, QTOF and orbitrap and application solutions.Experience with sample preparation from tissues, cells, and biofluids as needed to enable quantitative workflows for drug discovery programs.Experience in PTM analysis (phosphorylation and ubiquitination) and targeted proteomics.Experience with MaxQuant, Skyline and Tracefinder, Protein Pilot, Proteome Discoverer. Must be able to maintain UPLC/Mass spec for routine operations.Prior in vitro assays and in vivo pharmacology experience is a big plus.

Knowledge / Skills / Abilities:

Demonstrated time management and multi-tasking skills, ability to effectively prioritize workload and manage changes in direction. Demonstrated ability to lead and manage other scientist and associates. Demonstrated ability for attention to details and concern for impact. Effective communication skills with the ability to give and receive feedback, both verbally and in writing. Ability to work in a team environment and independently as required. Ability to work in a fast-paced environment. Well organized and adaptable to changes. Computer skills: knowledge of internet research, MS Word, Excel, Outlook, and PowerPoint. Ability to learn instrument and data analysis software.

Physical Requirements:

· Must be able to work in an office environment with minimal noise conditions

· Must be able to work in a lab setting with exposure to Animals/biohazards /Chemicals (List

specific Chemicals)

· Must not have animal allergies to applicable species in this facility.

· Must be able to work in environment with variable noise levels.

· Ability to stand/Sit/walk for long periods of time.

· Ability to Lift 10 lbs routinely.

· Ability to push/pull 10 lbs. routinely/often/occasionally

· Clarity of vision.

· Ability to identify and distinguish colors.

· Must be able to perform activities with repetitive motions.

· Ability to climb ladders/stairs/scaffolding.

· Ability to work in variable temperatures high to freezing.

· Inside/outside working conditions.

Anticipated base pay range: $121,924 to $170,462

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job-related duties as requested by Management.

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