DMPK Director
2 weeks ago
Recludix Pharma Inc is seeking an experienced DMPK Director to lead our small molecule drug discovery and development efforts in inflammation and oncology. The successful candidate will have strategic and scientific oversight of our small molecule portfolio and will manage the in vitro and in vivo PK, ADME and bioanalytical assays.
Responsibilities:- Design, plan, execute, interpret and report scientific experiments for DMPK activities.
- Provide leadership and strategic direction for DMPK in inflammatory/autoimmune disease and oncology programs.
- Contribute to and influence the DMPK components in the screening funnel and criteria for compound selection and advancement of research programs into development.
- Implement/manage quantitative bioanalysis of plasma and other biological matrices to support pharmacokinetic, toxicokinetics, and in vitro ADME analyses of novel small molecule therapeutics.
- Conduct PK and PK/PD modeling using non-compartmental and compartmental models.
- Responsible for reviewing BA and TK reports from nGLP and GLP tox studies.
- Organize and maintain data.
- Present data at project team meetings.
- Guarantee the prompt completion and review of high-quality DMPK reports.
- Contribute to nonclinical PK/ADME sections in regulatory documents (e.g., IB, IND, etc...).
- Actively participate on program teams as a key representative of nonclinical sciences.
- PhD and 8+ years of industry experience in DMPK supporting programs transitioning into development.
- Expertise in monitoring, managing and translating studies across discovery and development.
- Experience with small molecule drug development, including modelling of dose projections.
- Strong scientific leadership, creativity, problem-solving abilities and a track record of managing external partners.
- Experience with development of Immunology therapeutics highly desirable.
- Excellent communication, presentation, writing, coaching skills.
-
Senior DMPK Scientist
2 weeks ago
San Diego, California, United States Kumquat Biosciences Inc Full timeJob Title: DMPK LeadKumquat Biosciences is a pioneering biotechnology company dedicated to the discovery and development of innovative drugs to revolutionize cancer treatments. Our team of experts brings together a unique blend of scientific expertise and industry experience to translate cutting-edge research into novel therapeutics.We are seeking a highly...
-
Executive Director, DMPK
2 weeks ago
San Diego, California, United States Neurocrine Biosciences Full timeAbout the RoleWe are seeking an experienced Executive Director to lead our Preclinical Pharmacokinetics function within the Preclinical Development organization. As a key member of our team, you will provide strategic leadership and oversight to ensure the successful development of clinical candidates with acceptable drug development characteristics.Key...
-
Executive Director, DMPK
4 weeks ago
San Diego, California, United States Neurocrine Biosciences Full timeAbout the RoleWe are seeking a highly experienced and skilled Executive Director to lead our Preclinical Pharmacokinetics function within the Preclinical Development organization at Neurocrine Biosciences. As a key member of our team, you will be responsible for providing strategic leadership and oversight to ensure the successful development of clinical...
-
San Francisco, California, United States Eli Lilly and Company Full timeAbout the RoleWe are seeking a highly skilled and experienced Director, Drug Metabolism and Pharmacokinetics to join our team at Eli Lilly and Company. As a key member of our research organization, you will be responsible for providing scientific leadership and strategic direction to research project teams, ensuring the successful advancement of research...
-
Director of Radiochemistry
5 days ago
San Diego, California, United States Bristol-Myers Squibb Full timeJob Title: Director/Associate Director, RadiochemistryJoin Bristol-Myers Squibb, a leading biotechnology company, as a Director/Associate Director of Radiochemistry. This role offers a unique opportunity to lead the Discovery Radiochemistry group within the Chemistry Department, driving innovation and excellence in radiochemical strategies to support drug...
-
Director of Radiochemistry
2 days ago
San Diego, California, United States Bristol-Myers Squibb Full timeJob Title: Director/Associate Director, RadiochemistryJoin Bristol-Myers Squibb, a leading biotechnology company, as a Director/Associate Director of Radiochemistry. In this role, you will lead the Discovery Radiochemistry group within the Chemistry Department, driving innovation and excellence in radiochemical strategies to support drug discovery and...
-
Director/Associate Director, Radiochemistry
2 weeks ago
San Diego, California, United States Bristol-Myers Squibb Full timeJob SummaryBristol-Myers Squibb is seeking a highly skilled and experienced Director/Associate Director of Radiochemistry to lead the Discovery Radiochemistry group within the Chemistry Department. The successful candidate will be responsible for developing and implementing radiochemical strategies to support drug discovery and therapeutic programs.Key...
-
South San Francisco, California, United States Frontier Medicines Full timeJob DescriptionFrontier Medicines is seeking a highly skilled and experienced Senior Manager/Associate Director in CMC Development to join our team. As a key member of our CMC Development team, you will play a crucial role in advancing our small molecule pipeline. Your responsibilities will include driving the development and manufacturing of drug...
-
Process Chemistry Director
1 week ago
South San Francisco, California, United States Frontier Medicines Full timeJob Title: Director/Sr. Director, Head of Process ChemistryFrontier Medicines is seeking a highly motivated individual to lead our Process Chemistry team in our South San Francisco office. As a key member of our development team, you will be responsible for developing scalable manufacturing processes for our small molecule pipeline.Key Responsibilities:Lead...
-
Associate Director of Analytical Development
2 weeks ago
South San Francisco, California, United States Septerna Full timeAbout the RoleWe are seeking an experienced and highly motivated Associate Director of Analytical Development to manage and drive analytical development and quality control activities across our small molecule drug discovery and development programs. Reporting to the Senior Director, CMC, this individual will fill a critical role as the subject matter expert...
-
Associate Director of Analytical Development
5 days ago
San Francisco, California, United States Septerna Full timeAbout the RoleWe are seeking an experienced and highly motivated Associate Director of Analytical Development to manage and drive analytical development and quality control activities across our small molecule drug discovery and development programs.This individual will fill a critical role as the subject matter expert (SME) and functional lead, contributing...
-
San Francisco, California, United States BioSpace, Inc. Full timeJob DetailsCompany OverviewNurix Therapeutics is a biopharmaceutical company dedicated to the discovery, development, and commercialization of innovative small molecule therapies for cancer and immune disorders. Leveraging its expertise in E3 ligases and proprietary DNA-encoded libraries, Nurix has developed DELigase, an integrated discovery platform to...
-
Senior Director DMPK
1 month ago
san francisco, United States Meet Full timePosition Overview: We are seeking a highly experienced and strategic Senior Director of Drug Metabolism and Pharmacokinetics (DMPK) to lead DMPK department for one of our clients. In this critical role, you will be responsible for overseeing the development and implementation of DMPK strategies that support our drug discovery and development programs. This...
-
Senior Director DMPK
1 month ago
san francisco, United States Meet Full timePosition Overview: We are seeking a highly experienced and strategic Senior Director of Drug Metabolism and Pharmacokinetics (DMPK) to lead DMPK department for one of our clients. In this critical role, you will be responsible for overseeing the development and implementation of DMPK strategies that support our drug discovery and development programs. This...
-
Senior Director DMPK
2 months ago
South San Francisco, United States Meet Full timePosition Overview: We are seeking a highly experienced and strategic Senior Director of Drug Metabolism and Pharmacokinetics (DMPK) to lead DMPK department for one of our clients. In this critical role, you will be responsible for overseeing the development and implementation of DMPK strategies that support our drug discovery and development programs. This...
-
Senior Director DMPK
2 months ago
South San Francisco, United States Meet Full timePosition Overview: We are seeking a highly experienced and strategic Senior Director of Drug Metabolism and Pharmacokinetics (DMPK) to lead DMPK department for one of our clients. In this critical role, you will be responsible for overseeing the development and implementation of DMPK strategies that support our drug discovery and development programs. This...
-
Director, DMPK
3 months ago
San Francisco, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Senior Director, Toxicology
1 month ago
san diego, United States Meet Full timeDirector/Senior Director, Toxicology*candidates can work out of San Diego, CA or Louisville, CO office - generous relocation package provided*Meet has partnered with a large, well-established pharmaceutical company that is looking for a Director or Senior Director of Preclinical Toxicology to join their team!Key ResponsibilitiesLead the team to design and...
-
Senior Director, Toxicology
1 month ago
San Diego, United States Meet Full timeDirector/Senior Director, Toxicology*candidates can work out of San Diego, CA or Louisville, CO office - generous relocation package provided*Meet has partnered with a large, well-established pharmaceutical company that is looking for a Director or Senior Director of Preclinical Toxicology to join their team!Key ResponsibilitiesLead the team to design and...
-
Senior Director, Toxicology
1 month ago
san diego, United States Meet Full timeDirector/Senior Director, Toxicology*candidates can work out of San Diego, CA or Louisville, CO office - generous relocation package provided*Meet has partnered with a large, well-established pharmaceutical company that is looking for a Director or Senior Director of Preclinical Toxicology to join their team!Key ResponsibilitiesLead the team to design and...
-
Senior Director, Toxicology
1 month ago
San Diego, United States Meet Full timeDirector/Senior Director, Toxicology*candidates can work out of San Diego, CA or Louisville, CO office - generous relocation package provided*Meet has partnered with a large, well-established pharmaceutical company that is looking for a Director or Senior Director of Preclinical Toxicology to join their team!Key ResponsibilitiesLead the team to design and...
-
South San Francisco, California, United States Frontier Medicines Full timeSenior Manager/Associate Director, CMC DevelopmentFrontier Medicines is seeking a highly skilled Senior Manager/Associate Director to lead our CMC Development team. As a key member of our organization, you will be responsible for driving the development and manufacturing of drug substances, overseeing internal and external resources, and collaborating...