Senior Research Associate
3 weeks ago
Description & Requirements
Detailed studies of cellular signaling networks related to protein phosphorylation, ubiquitylation or acetylation Unveiling the targets of drugs or identifying protein interactors through chemical proteomics technologies and affinity purification MS Developing biological understanding of response and resistance to therapy Proteogenomic studies of a wide range of cancers Developing and optimizing new, broadly enabling proteomic technologies including targeted, quantitative MS assay development for proteins and modifications of high biological or clinical interest.Successful candidates will work in many of these areas together with an interdisciplinary team of clinicians, biologists, computational and proteomics scientists to deeply characterize and understand the proteomes of tumor-derived material, cells and biofluids.
Candidates must have:
Bachelor’s degree in Chemistry or Biochemistry and 6+ years of experience in a research laboratory, or a Master’s degree in analytical chemistry or biochemistry and 4+ years of experience. 3+ years of experience in MS-based proteomics; significant experience with MS, HPLC, peptide and protein separation. High productivity, evidenced by high-quality collaborative science and research publications in peer reviewed journals on which they are named co-authors. Able to work in a team. Excellent verbal and written communication skills.Hands on skills and knowledge in one or more of the following areas will be considered an advantage:
Knowledge of various scientific databases and experience with publishing and presenting experimental results highly desirable. Experience in statistical and/or computational analysis of proteomics data. Posttranslational modification analysis such as phosphorylation, ubiquitylation, etc. Cell biology/ biochemical methods to understand protein function.Characteristic Duties:
Works with senior staff to set experimental strategy, project goals and timelines and works directly with collaborator teams to drive projects toward successful completion. Helps define experimental design. Carries out detailed LC- and nanoLC-MS/MS analyses of complex, biologically derived protein, peptide and small molecule mixtures, including PTMs. Consults scientific literature and collaborates with other researchers from the scientific community as needed. Tracks and compiles results. Helps develop and optimize new technologies and protocols; assists with the training of lab personnel on new methodologies. Utilizes laboratory automation instrumentation to execute established proteomic workflows. Helps to produce and isolates samples for proteomics studies using cell culture techniques, immunoprecipitation, subcellular fractionation methods and protein sample preparation from tissues and/or biofluids. Utilizes other protein biochemistry and proteomic techniques such as western blotting, multidimensional chromatography and in-gel digestion to meet project and research goals. Operates and maintains one or more LC-mass spectrometers (Thermo QExactive/Exploris-series, Thermo Lumos-series, Bruker timsTOF) and HPLC systems for peptide separation and analysis. Helps ensure that project support, such as software, instrument spares, lab reagents, etc. are in place in accordance with project requirements. Prepares detailed technical documents describing procedures and results. Independently prepares posters and assists in preparation of reports and manuscripts for meetings and peer-reviewed literature. Will assist supervisory scientists and collaborators with writing and editing as needed. Orders supplies, helps to maintain stock of common expendables and reagents for Proteomics lab.-
Senior Research Associate
7 days ago
Cambridge, United States Harvard University Full timeThe Senior Research Associate (Sr. RA) will work closely with a diverse team of scholars at The People Lab (TPL) who are passionate about conducting collaborative, applied, data-driven research on key priorities in government. Projects range from: ho Research Associate, Research, Associate, Senior, Technology, Education, Skills
-
Cambridge, United States Massachusetts Institute of Technology Full timeSENIOR RESEARCH SUPPORT ASSOCIATE, Picower Institute for Learning and Memory, to join the Nedivi Lab which is investigating the contribution of different classes of interneurons to circuit development and their relative contribution to neuronal plast Associate, Research, Support, Chemistry, Senior, Technology, Education
-
Senior Research Support Associate, Li lab
2 weeks ago
Cambridge, United States Massachusetts Institute of Technology Full timeSENIOR RESEARCH SUPPORT ASSOCIATE, Biology, to join Gene-Wei Li's lab and provide technical assistance to high-throughput genomics projects and computational analysis. Primary responsibilities will include working with investigators to develop and va Research, Associate, Support, Technical Support, Senior, Technology, Education, Biology
-
Cambridge, United States Repertoire Immune Medicines Full timeJob DescriptionJob DescriptionResearch Associate II/Senior Research AssociateProtein Engineering & Molecular SciencesCompany OverviewRepertoire Immune Medicines is a biotechnology company working to unlock and direct the remarkable power of the human immune system to treat cancer, autoimmune disease and infectious disease. The company was founded by Flagship...
-
Senior Research Support Associate, Choi Lab
2 weeks ago
Cambridge, United States Massachusetts Institute of Technology Full timeREQUIRED: high school diploma or its equivalent; prior exposure to a research lab; ability to work both independently and collaboratively within a small team; and strong organizational, communication, and time-management skills. PREFERRED: bachelor's degree in the life sciences (e.g., biology, neuroscience, biomedical engineering) or a related discipline,...
-
Cambridge, United States Massachusetts Institute of Technology Full timeREQUIRED: high school diploma or its equivalent, exposure to a research laboratory, an interest in biology, and the ability to work independently and as part of a team. PREFERRED: bachelor's degree in biology or related field, e.g., biochemistry, neuroscience, etc.; lab experience with some of the following methods--immunocytochemistry, fluorescence...
-
Senior Research Support Associate, Li lab
2 weeks ago
Cambridge, United States Massachusetts Institute of Technology Full timeREQUIRED: high school diploma or its equivalent, exposure to a research lab, meticulous attention to detail, strong communication skills, and ability to work as part of a team. Seek a self-motivated and highly organized person who can work independently and demonstrates a commitment to exceeding quality standards and providing exceptional services....
-
Cambridge, Massachusetts, United States Proclinical Staffing Full timeProclinical is seeking a (Senior) Research Associate, Oligonucleotide Chemistry to join a n established research organization in Cambridge, MA, in their oligonucleotide chemistry team. Job Responsibilities:Supporting the synthesis, purification and characterization of oligonucleotidesSupport ordering and general upkeep of RNA synthesizers and other related...
-
Cambridge, United States Massachusetts Institute of Technology Full timeREQUIRED: high school diploma or its equivalent; exposure to a research lab; demonstrated ability to independently multitask and execute, analyze, and troubleshoot experiments; excellent organizational, analytical, and oral and written communication skills; self-motivation; and work with others. PREFERRED: B.S./B.A. in biology or related science field, one...
-
Senior Legal Researcher
1 week ago
Cambridge, United States Harvard University Full timeBasic Qualifications Master's degree (or alternatively a law degree from the US or abroad) and 5+ years of experience (including in an educational context) in conducting legal research and writing analyses of such research. Additional Information This is a term appointment currently expected to extend through 6/30/25, with potential for renewal subject to...
-
Senior Clinical Research Associate
1 day ago
Cambridge, Massachusetts, United States Philips Full timeJob TitleSenior Clinical Research AssociateJob DescriptionYour role:Owning the overall study process and adherence to clinical trial procedures by keeping oversight, identifying possible problems/risks, creating mitigation plans, and taking actions or corrective actions using timely communication for daily monitoring and site mgmt.Supporting site...
-
Research Associate
4 weeks ago
Cambridge, United States LifeCanvas Technologies Inc. Full timeLifeCanvas Technologies is an MIT spinoff venture aiming to revolutionize the way we see and study biological systems to elevate human health. LifeCanvas offers cutting-edge technologies and end-to-end solutions that enable holistic molecular imaging of biological systems to accelerate the pace of breakthrough discoveries in science and the development of...
-
Research Associate
4 weeks ago
Cambridge, United States LifeCanvas Technologies Inc. Full timeLifeCanvas Technologies is an MIT spinoff venture aiming to revolutionize the way we see and study biological systems to elevate human health. LifeCanvas offers cutting-edge technologies and end-to-end solutions that enable holistic molecular imaging of biological systems to accelerate the pace of breakthrough discoveries in science and the development of...
-
Research Associate
1 month ago
Cambridge, United States LifeCanvas Technologies Inc. Full timeLifeCanvas Technologies is an MIT spinoff venture aiming to revolutionize the way we see and study biological systems to elevate human health. LifeCanvas offers cutting-edge technologies and end-to-end solutions that enable holistic molecular imaging of biological systems to accelerate the pace of breakthrough discoveries in science and the development of...
-
Research Associate, Analytical Development
2 weeks ago
Cambridge, United States Garuda Therapeutics Full timeGaruda Therapeutics is pioneering the development of off-the-shelf hematopoietic stem cell (HSC)-based cellular therapies for treating patients with blood, bone marrow, immune, and metabolic disorders. The company uses state-of-the-art technologies in developmental biology, gene-editing, stem cells, and mechanobiology to engineer safe, compatible HSCs in...
-
Senior Research Associate, Biology
2 weeks ago
Cambridge, United States Delphia Therapeutics Full timeAbout Us:Delphia is igniting a new field of therapeutics in hopes to transform the care of cancer patients. Together, we are working to advance first-in-class targeted cancer medicines leveraging Activation Lethality, a new field of cancer biology centered on cancer’s surprising vulnerability to oncogene overactivation. While a bold idea, activation...
-
Senior Research Associate, Biology
2 weeks ago
Cambridge, United States Delphia Therapeutics Full timeAbout Us:Delphia is igniting a new field of therapeutics in hopes to transform the care of cancer patients. Together, we are working to advance first-in-class targeted cancer medicines leveraging Activation Lethality, a new field of cancer biology centered on cancer’s surprising vulnerability to oncogene overactivation. While a bold idea, activation...
-
Senior Research Associate, Biology
4 days ago
Cambridge, United States Delphia Therapeutics Full timeAbout Us:Delphia is igniting a new field of therapeutics in hopes to transform the care of cancer patients. Together, we are working to advance first-in-class targeted cancer medicines leveraging Activation Lethality, a new field of cancer biology centered on cancer’s surprising vulnerability to oncogene overactivation. While a bold idea, activation...
-
Research Associate
2 weeks ago
Cambridge, United States Harvard University Full timeBasic Qualifications Bachelor's degree required, along with research experience gained through work experience, internships, or academic work. Additional Information This position is a fully benefits-eligible term appointment ending one year from date of hire, with possibility of renewal. Learn more about our work culture and see yourself at Harvard...
-
Research Associate, Analytical Development
2 weeks ago
Cambridge, United States Garuda Therapeutics, Inc. Full timeJob DescriptionJob DescriptionGaruda Therapeutics is pioneering the development of off-the-shelf hematopoietic stem cell (HSC)-based cellular therapies for treating patients with blood, bone marrow, immune, and metabolic disorders. The company uses state-of-the-art technologies in developmental biology, gene-editing, stem cells, and mechanobiology to...
