Senior Clinical Scientist
5 days ago
Clinical Scientist (CTH Director or Sr. Director level)
Hybrid in South San Francisco, CA
Our client is a clinical-stage biopharmaceutical company focused on developing differentiated oncology therapeutics to address unmet medical needs in difficult-to-treat cancers. The organization is advancing a pipeline of innovative oncology assets, including targeted therapies and antibody-drug conjugates (ADCs), through global clinical development and strategic collaborations.
This is a 6-month initial contract engagement with an expectation to convert to a full-time role in 2026. Candidates must be in commutable distance to work in the bay area office one day per week.
- Responsibilities:
Lead the Clinical Development Plan (CDP) for assigned oncology programs, including strategic roadmap, indication prioritization, and milestone planning. - Provide clinical and scientific input into protocol design, study endpoints, and data analysis plans for early- and late-phase oncology studies.
- Serve as the scientific lead on cross-functional study teams; author and review protocols, investigator brochures, clinical study reports, and regulatory submission documents (INDs, CTAs, briefing books).
- Partner with Clinical Operations to support study execution and data review, providing scientific oversight and issue resolution throughout trial conduct.
- Work closely with Biostatistics to define statistical analysis plans, endpoint development, and data review strategies.
- Contribute to KOL engagement, investigator meetings, and external collaborations to ensure alignment of study design and scientific priorities.
- Represent Clinical Science in governance meetings and cross-functional development discussions.
Qualifications:
- Ph.D or PharmD is required with 10 years of relevant industry experience
- Strong Oncology experience is required
- Deep understanding of oncology biology, translational science, pharmacokinetics/pharmacodynamics (PK/PD), and early clinical endpoints.
- Proven experience developing and driving Clinical Development Plans for oncology programs.
- Deep understanding of oncology biology, translational science, and clinical trial endpoints.
- Experience contributing to or leading global, multi-site clinical trials (Phase I–III).
- Strong scientific writing, data interpretation, and communication skills.
- Background with antibody-drug conjugates (ADCs) is preferred
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