Scientist

1 week ago

Worcester, United States Synectics Inc Full time
Job DescriptionJob Description

Job Description

  • The Biotherapeutics and Genetic Medicine Group at Company Bioresearch Center is seeking a highly motivated scientist for rAAV analytical characterization for gene therapy in a newly established rAAV Research and Production team.

  • Wwork collaboratively with our therapeutic area teams to advance Company's rAAV pipeline.

  • Assisting with the development and execution of analytical methods to support preclinical studies.

  • Assist in the development and application of molecular and cell-based assays (e.g., ELISA, SDS-PAGE, WB, WES, Endotoxin assay)

  • Maintain and culture cells or assist in AAV production as needed

  • Analyze experimental data, generating plots and summarizing results and conclusions

  • Maintain a comprehensive Electronic Lab Notebook documenting experiments

  • Maintain a high level of productivity in the team with clear daily, detailed, and accurate documentation of experiments

  • Collaborate with team members to meet project goals, and advance novel vectors into pipeline

  • Author technical reports and protocols

  • Understand and enforce company culture, teamwork, safety, appropriate handling of materials in an BSL2 environment

  • Perform all activities in compliance with applicable regulations, Company's policies and guidelines

  • Bring a "can do" spirit to work and deliver on other responsibilities as assigned

Qualifications;

  • Bachelor's with 2-3 years of experience; OR

  • Master's in Biology or related discipline

  • Open to PhD

  • 3-5 years of relevant experience

  • Experience in molecular assay development and optimization (e.g., ddPCR, WB, WES, SDS-PAGE)

  • Requires a versatile individual, who can work in development and analytical activities to advance pipeline.

  • Experience in rAAV production using mammalian cell platforms

  • Experience in cell culture work (e.g., maintenance, transfection, transduction)

  • Ability to work effectively in a highly collaborative and dynamic environment

  • Successful track record of working in high-growth and dynamic organizations

  • Excellent verbal and written communication skills

  • Evidence of "hands-on" experience and expertise

  • Organized and detail oriented with a passion to deliver quality results

  • Biotechnology experience in rAAV Process and Analytical Development.

  • Team Player

  • ELISA, MSD, western blot, ddPCR/molecular assay development would be a plus

  • Viral vector experience required

Benefits:

Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.

Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.

Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.

Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.

Synectics is an equal opportunity employer.

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