Scientist

4 days ago

Worcester, United States Synectics Inc Full time
Job DescriptionJob Description

Job Description:

  • As an integral member of the GM team this individual will be critical in activities related to mRNA-LNP development, optimization, characterization, including LNP formulation (NanoAssemblr or Jet mixer), size, and surface potential measurement.

  • As one of the key team members this individual will work with the manager and scientists across different functional groups to discover and develop next generation non-viral genetic medicine.

  • You will be relied on as a technical contributor to assess the assigned tasks that involve direct application of your knowledge.

  • Help in developing, producing, and characterizing lipid based nucleic acid formulations with targeting moieties for innovative drug products to support multiple internal programs.

  • Work closely with manager and cross-functional team members on multiple projects simultaneously to collect and analyze data on project basis.

  • Under manager's supervision interpret and summarize experimental data. Present experimental results at meetings as needed.

  • Assist in ordering supplies from internal inventory and prepare reagents & other supplies necessary for formulation work.

  • Maintain laboratory electronic notebooks (ELN) in compliance with the Laboratory Notebook Policy.

  • Stay updated and in compliance on all departmental and corporate training.

Qualifications:

  • BS in Chemistry, Chemical Engineering, Biological Engineering, or a related field with a minimum of 3-5 years of relevant industry experience.

  • MS in biology, chemistry, biomedical engineering, or related field with 0-2 years of nanoparticle design and characterization experience.

  • Experience with tangential flow filtration (TFF) and sterile filtration.

  • Experience with LNP formulations.

  • Working knowledge of related tools/software (Prism, FlowJo, FACSDiva etc.).

  • Laboratory hands-on experience with nanoparticle formulation and characterization and stability studies.

  • Self-motivated, hard-working, detail-oriented, resourceful, and able to work in a fast-paced team environment with demonstrated problem solving and perseverance skills.

  • Good Computer skills including word processing, Excel, PowerPoint and relevant scientific software.

  • Builds strong relationships with peers and cross functionally with partners to enable higher performance.

  • Learns fast, grasps the "essence "and can change course quickly where indicated.

  • Open to suggestions and experimentation for improvement.

  • Strong interpersonal and communication skills with proven ability to work within a team environment.

  • Hands-on experience with tangential flow filtration (TFF) and sterile filtration.

  • Excellent verbal and written skills and the ability to clearly present scientific concepts and results.

  • Familiar with analytical techniques including but not limited to DLS, zeta potential, SDS-PAGE, ELISA, SEC and RiboGreen assay.

Benefits:

Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.

Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.

Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.

Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.

Synectics is an equal opportunity employer.

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