Scientist II or Senior Scientist I, Biologics ARD

2 weeks ago


Worcester, Massachusetts, United States AbbVie Full time
Job Overview

Absorb the opportunity to join AbbVie's Biologics Analytical Research & Development team as a seasoned scientist with a strong background in mass spectrometry and protein characterization. This role offers a unique chance to work with global and cross-functional teams to drive exceptional science and innovative product development strategies.

Key Responsibilities
  • Characterize monoclonal antibodies, Antibody-Drug-Conjugates, novel multi-specifics, fusion proteins, and gene therapies using modern LC-MS instruments and techniques.
  • Compile and assess analytical data regarding function and stability of therapeutic biologic molecules to support candidate screening in high throughput.
  • Develop and manage strategic alignments with key stakeholders, revise and improve business workflows, manage project timelines and resources.
  • Collaborate with clients from various discovery and development functions to develop the optimal CMC development path for assigned discovery projects.
  • Operate in a matrix team environment, aligning across and executing shared departmental and divisional strategies.
  • Present data at internal and external professional conferences and prepare manuscripts for publication in peer-reviewed journals or patent applications.
Requirements
  • BS or equivalent education with typically 7 or more years of experience or MS or equivalent education with typically 5 or more years of experience.
  • At least 2 years of experience in comprehensive characterization of monoclonal antibodies in an industry setting.
  • Experience with characterization of genetic medicines, including AAVs and LNPs, is highly desired.
  • Deep understanding of protein characterization by LC/ESI-HR-MS and insights into the causes of protein degradation.
  • Knowledge of functional excipient degradation pathways is a plus.
  • Experience in determination of PTM and chemical modifications and their influence on the molecule's function and structure.
  • Additional robotics expertise and protein analytical experience is beneficial.
AbbVie Competencies
  • Builds strong relationships with peers and cross-functionally with partners outside of teams to enable higher performance.
  • Learns fast, grasps the 'essence' and can change course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Level and compensation will be commensurate with experience. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.


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