Senior Research Associate/Associate Research Scientist/Research Scientist, Assay Development

2 months ago

San Jose, California, United States Accellix Full time
Job Description

Company Overview

Accellix is a leading provider of innovative solutions for the cell therapy industry. Our mission is to empower researchers and clinicians to harness the full potential of cell therapy by providing cutting-edge technology and expertise.

Job Summary

We are seeking a highly skilled and motivated Senior Research Scientist/Associate Research Scientist/Research Scientist to join our Assay Development team. The successful candidate will be responsible for developing and qualifying flow cytometry assay panels on our platform, collaborating with cross-functional teams, and providing analysis and feedback for developing automated analysis software.

Key Responsibilities

  • Assay Development
    • Develop and qualify flow cytometry assay panels on the Accellix platform, including optimization of formulations and protocols
    • Collaborate with cross-functional teams while following design and development plans, executing assay verification and validation, and ensuring all assay requirements are satisfied
  • Collaboration and Communication
    • Provide analysis and feedback for developing automated analysis software
    • Follow good manufacturing practices (GMP) in lab, clearly document experimental procedures and results, and assist team in maintaining inventory of lab supplies and reagents
    • Participate in drafting and editing protocols for assay kit manufacturing and QC, and in tech transfer of new assays to the manufacturing team
    • Present updates on projects and initiate brainstorming/troubleshooting discussions within the team and to external customer audiences
  • Teamwork and Leadership
    • Promote a strong working relationship with others in the lab, facilitate open communication, proactively identify and address issues, and support other team members to meet deadlines and manage shifting priorities

Requirements

  • Senior Research Scientist: BS with 4+ years or MS with 2+ years, Associate Research Scientist: BS or MS with 8+ years, Research Scientist: PhD 0-2 years of relevant Industry experience
  • Experience with experimental design and execution of flow cytometry assays, including antibody titrations, and optimizing and troubleshooting multicolor assays
  • Experience with flow cytometry data analysis using FlowJo or similar analysis software
  • Demonstrated ability to manage multiple projects, meet goals in a timely fashion, communicate delays and escalate challenges immediately
  • Ability to design, execute, and analyze experiments with minimal oversight
  • Ability to communicate effectively and collaborate within and across teams

Desired Qualifications

  • Experience with generating and optimizing compensation matrices to address fluorescence spectral overlap in multiparametric flow data
  • Familiarity with common biomarkers found on leukocytes, and/or familiarity with cell-based therapies and cellular engineering
  • Experience with product development or instrument automation in an industry setting
  • Experience with assay transfer to internal or external collaborators
  • Experience with good documentation practices (GDP) and with drafting and reviewing documents such as SOPs and development reports

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