Postdoctoral Research Fellow
3 weeks ago
Cleveland Clinic Health System is seeking a highly motivated and talented Postdoctoral Fellow to join our team. As a Postdoctoral Fellow, you will have the opportunity to work in a dynamic and collaborative research environment, contributing to cutting-edge projects in the field of retinal disease and gene therapy.
Job Summary:We are looking for a highly motivated individual with a PhD or MD/PhD in a relevant area to join our team. The successful candidate will have a strong interest in retinal disease, gene therapy, and cellular and molecular biology. The position will provide practical training and experience in a research setting, under the direct supervision of a Cleveland Clinic Principal Investigator.
Responsibilities:- Design and execute independent research projects to investigate the cellular and molecular mechanisms of reactive astrocytes in the eye and optic nerve.
- Utilize high-throughput genomic and proteomic techniques to identify critical genes and pathways involved in reactive astrocyte functions.
- Employ rodent ocular disease models, imaging, and behavioral assays to study the molecular, transcriptional, and functional consequences of cyclic-nucleotide signaling in reactive retinal and optic nerve astrocytes.
- Collaborate with team members to interpret data, generate hypotheses, and design follow-up experiments.
- Contribute to publishing research findings in peer-reviewed journals and presenting results at conferences and seminars.
- PhD or MD/PhD in a relevant area.
- Strong interest in retinal disease, gene therapy, and cellular and molecular biology.
- Previous experience in a research or academic setting.
- Scientific writing experience.
- Experience with rodent animal handling and surgical practices.
- Preparation of bulk and scRNAseq libraries, and/or protein samples for mass spec analysis.
- Understanding or interest in astrocyte-immune, astrocyte-astrocyte, and astrocyte-neuron signaling in disease.
- AAV gene therapy development experience or interest.
Cleveland Clinic Health System offers a competitive salary and benefits package, as well as opportunities for professional growth and development. We are an equal opportunity employer and welcome applications from diverse candidates.
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