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Medicinal Chemistry Project Leader
2 months ago
Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Our proprietary PROTAC Discovery Engine platform enables us to engineer proteolysis targeting chimeras, or PROTAC targeted protein degraders, that harness the body's natural protein disposal system to selectively and efficiently degrade and remove disease-causing proteins.
Job SummaryWe are seeking a highly experienced Medicinal Chemistry Project Leader to lead our neuroscience therapeutic area research projects towards IND-track nomination. The successful candidate will have a strong track record of leading cross-functional teams and driving project advancement through effective leadership, scientific expertise, and strategic decision-making.
Key Responsibilities- Lead multiple target-oriented PROTAC projects to deliver milestone decisions in line with target project profiles and timelines.
- Design and execute drug-discovery experiments on a project basis, leveraging synthetic and medicinal chemistry-related scientific and technological principles.
- Collaborate with external CRO resources to ensure synthetic and PK/ADME data needs are fulfilled according to agreed timelines and standards.
- Provide transparent, coherent, and focused updates to manager and company executives on request and represent company interests at conferences and in scientific matters to external organizations as needed.
- Contribute novel insights and analysis to further develop and evolve the PROTAC platform.
- PhD in Medicinal Chemistry with 12+ years of pharma/biotech-based drug discovery experience.
- Proven track record of leading neuroscience research projects towards IND-track nomination.
- Strong leadership and project management skills, with experience managing cross-functional teams.
- Excellent scientific expertise in synthetic and medicinal chemistry, with a strong understanding of PROTAC technology.
- Ability to communicate complex scientific concepts effectively to both technical and non-technical audiences.
Arvinas is proud to offer a competitive package of base and incentive compensation, as well as a comprehensive benefits program designed to support the health, wellness, and financial security of our employees and their families. We are an Equal Opportunity Employer.
