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Biological Research Specialist
2 months ago
Location:
Cambridge, MA
About the Opportunity:
The Healthcare Businesswomen's Association is in search of a dedicated, innovative, and team-oriented scientist to become a vital part of our Biological Chemistry (BC) team. This role is centered on the hands-on exploration and development of pioneering cancer therapies.
Our focus lies in early-stage drug discovery, where we aim to comprehend and leverage the molecular dynamics of novel cancer targets to facilitate the discovery, characterization, and enhancement of small molecule therapeutics.
Key Responsibilities:
- Design, develop, and refine biochemical and biophysical assays utilizing various detection methodologies to identify and characterize cancer targets and small molecule modulators.
- Measure binding affinity and kinetics, while elucidating the binding modes of ligands to target proteins.
- Explore and implement cutting-edge technologies and innovative assay strategies to propel drug discovery initiatives.
- Collaborate with medicinal chemistry teams to assess compound structure-activity relationships (SAR) and modes of action.
- Engage in open communication and collaboration with a diverse team of interdisciplinary scientists to challenge existing paradigms and advance scientific understanding.
Essential Qualifications:
- This role is based in Cambridge, MA and does not offer remote work options.
- A minimum of a bachelor’s degree in Biochemistry, Biophysics, Enzymology, or a related discipline, accompanied by at least 1 year of relevant laboratory research experience, or a master’s degree with up to 1 year of pertinent experience.
- A solid grasp of protein functionality and enzymatic mechanisms, with experience in developing biochemical and/or biophysical assays for protein targets and small molecule inhibitors.
- Strong technical skills at the laboratory bench, a keen desire to learn, and a readiness to tackle complex scientific challenges.
- Proven experience in collaborating with multidisciplinary project teams.
- Familiarity with one or more of the following assay techniques: fluorescence-based assays (e.g., HTRF, FP, or quench assays) and label-free technologies (e.g., SPR, ITC, DSF, or mass spectrometry).
- Demonstrated ability to analyze, interpret, and present data clearly and concisely.
- Excellent team player with strong communication and interpersonal skills.
Desirable Qualifications:
- Practical experience with automation to facilitate medium to high throughput assays.
Compensation:
Salary range: $66,000 - $99,000
Benefits and Rewards:
Discover the various ways we support your personal and professional growth through our comprehensive benefits package.
Commitment to Diversity and Inclusion:
The Healthcare Businesswomen's Association is dedicated to fostering an outstanding, inclusive work environment and building diverse teams that reflect the patients and communities we serve.
Equal Opportunity Statement:
We are proud to be an Equal Opportunity Employer and maintain a diverse workplace. We do not discriminate in recruitment, hiring, training, promotion, or other employment practices based on race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility and Reasonable Accommodations:
We are committed to working with and providing reasonable accommodations to individuals with disabilities.
