Next Generation Therapeutics Expert

18 hours ago


San Diego, California, United States Poseida Therapeutics, Inc. Full time

We are a leading biopharmaceutical company dedicated to developing next-generation cell and gene therapies with the capacity to cure severe diseases. Our research focus is on creating innovative treatments that address the limitations of current generation cell and gene therapeutics.

We are seeking an experienced Next Generation Therapeutics Expert to join our Gene Therapy team in San Diego, CA. As a Next Generation Therapeutics Expert, you will work closely with our Formulations, Molecular Biology, and Chemistry teams in the design of next-generation genetic medicine platforms and stay abreast of new gene therapy platform and mechanistic results from Poseida and other companies.

Your responsibilities may include managing and executing in vivo and in vitro pharmacology work from discovery to drug candidate nomination, and IND-enabling activities working closely with formulations, analytical chemistry, molecular engineering, and translational teams. You will also lead in vivo pharmacology activities in rodents and large animals, planning and executing studies to characterize the in vivo pharmacology (PK/PD, biodistribution), toxicology, safety, and efficacy of our genetic medicines systems.

The ideal candidate will have a Ph.D. in a scientific discipline (e.g., molecular biology, cell biology, pharmacology, toxicology, immunology, or other relevant scientific field) with 5+ years of relevant experience. A strong background/certification in toxicology and demonstrated expertise in the biology and relevant animal models of at least one of the following classes of genetic diseases: urea cycle disorders, inborn errors of amino acid, carbohydrate, or lipid metabolism, organic acidemia, lysosomal storage disorders, or congenital hematologic diseases, strong preference for experience with Hemophilia.

Estimated salary for this position is $130,000 - $150,000 per year, depending on education and experience. We offer a competitive compensation package, including benefits and opportunities for growth and development in a dynamic and collaborative environment.



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