Gene Therapy Research Specialist

1 day ago


San Diego, California, United States Poseida Therapeutics, Inc. Full time

Poseida Therapeutics, Inc. is a clinical-stage biopharmaceutical company that utilizes its unique genetic engineering platform technologies to create next-generation cell and gene therapies with the potential to cure severe diseases early in life. We are passionate about making an impact on patients' lives with the development of our CAR-T therapies in various cancers and gene therapies for rare diseases.

Job Description

We are searching for a skilled Research Scientist (Research Scientist I, Research Scientist II or Sr. Research Scientist) to join our Gene Therapy team in San Diego, CA. This position offers an exciting opportunity to discover and develop next-generation products using Poseida's best-in-class genome editing, gene insertion, and delivery technologies.

Responsibilities:
  • Manage and execute in vivo pharmacology work from discovery to drug candidate nomination, working closely with formulations, analytical chemistry, molecular engineering, and translational teams.
  • Lead in vivo pharmacology activities in rodents and large animals for Poseida's in vivo genetic medicines team, comprising platform discovery, feasibility assessment, therapeutic proof-of-concept, and candidate nomination.
  • Plan and execute studies in rodents and large animals to characterize the in vivo pharmacology (PK/PD, biodistribution), toxicology, safety, and efficacy of Poseida's genetic medicines systems, including hands-on work designing/validating/implementing in vivo disease models.

The ideal candidate will have a Ph.D. in a scientific discipline (e.g., molecular biology, cell biology, pharmacology, toxicology, immunology, or other relevant scientific field) with up to 5 years of relevant experience. Strong hands-on experience with complex drug formulations, such as nanoparticles and viral vectors, for in vivo gene therapy is highly valued. Experience with routine assays (qPCR and/or ddPCR, immune-staining (IHC/IFC), immunoassays (ELISA, MSD, Luminex) and Western blot) is also desirable.

Benefits

We offer a competitive salary and benefits package, including health insurance, retirement savings plan, and paid time off. The salary range for this position is $108,000 - $150,000 per year, depending on experience and qualifications.



  • San Diego, California, United States American Society of Hematology Full time

    Job SummaryWe are seeking a highly skilled Gene Therapy Research Specialist to join our team in San Diego, CA. The successful candidate will have a strong background in molecular biology, cell biology, or a related field and will be responsible for leading in vivo pharmacology activities, planning and executing studies, and collaborating with...


  • San Francisco, California, United States American Society of Gene & Cell Therapy Full time

    The American Society of Gene & Cell Therapy (ASGCT) is a leading professional organization in the field of gene and cell therapy. We are seeking a highly skilled policy specialist to join our team.As a policy specialist, you will play a critical role in advancing the mission of ASGCT by providing high-quality, science-based guidance to federal policymakers....


  • San Diego, California, United States Poseida Therapeutics, Inc. Full time

    About the Role:">Poseida Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing next-generation cell and gene therapies for rare diseases. We are seeking an exceptional Scientist to join our Gene Therapy team in San Diego, CA. This role offers an exciting opportunity to discover and develop innovative genetic medicines using Poseida's...


  • San Diego, California, United States Poseida Therapeutics, Inc. Full time

    Company OverviewPoseida Therapeutics, Inc. is a clinical-stage biopharmaceutical company that utilizes its proprietary genetic engineering platform technologies to create next-generation cell and gene therapies with the potential to cure diseases.Salary RangeThe estimated salary for this position is between $108,000 and $150,000 per year, depending on...


  • San Diego, California, United States Aequor Technologies Full time

    Aequor Technologies is hiring a Gene Therapy Operations Technician to work on our team in San Diego, CA. This is a 6+ month contract position with a salary range of $120,000 - $180,000 per year.In this role, you will be responsible for providing technical support for business continuity and decommissioning of networking systems, SCADA systems, and analytical...


  • San Diego, California, United States RPM ReSearch Full time

    RPM ReSearch, a preclinical Contract Research Organization based in San Diego, California, is seeking a highly skilled Scientific Account Manager for its Drug Development Services department. As a key member of the Sales and Operations Team, this individual will serve as a liaison between sponsors, internal research scientists, and business development team...


  • San Diego, California, United States RPM ReSearch Full time

    Job Description:RPM ReSearch is seeking an accomplished Ocular Research Scientist to develop and support in vivo models for small molecule, cell/gene therapy, and large molecule therapeutics.The successful candidate will have a broad knowledge of Ocular anatomy, physiology, and biochemistry. They must be able to perform ocular injections, such as...


  • San Francisco, California, United States HireMinds Full time

    Lead Researcher in Gene Delivery and FormulationsHireMinds is seeking an experienced Associate Director to lead the formulation team for non-viral gene therapy, focusing on strategic development, implementation, and oversight of pre-formulation, formulation development, tech transfer, scale-up, and manufacturing activities.This leadership position will...


  • San Francisco, California, United States HireMinds Full time

    About the RoleWe are seeking a highly skilled Senior Gene Therapy Formulation Lead to join our team at HireMinds in South San Francisco, CA.Job SummaryThe successful candidate will play a pivotal role within our research team, focusing on the strategic development, implementation, and oversight of pre-formulation, formulation development, tech transfer,...

  • Research Scientist

    3 weeks ago


    San Diego, California, United States Scripps Research Full time

    About UsScripps Research is a leading nonprofit biomedical institute that has been ranked as one of the most influential in the world for its impact on innovation.We are celebrating our 100-year legacy in 2024, marking a century of seminal discoveries in immunology, infectious diseases (such as COVID-19, flu, HIV), neuroscience, heart disease, cancer, and...


  • San Diego, California, United States The Scripps Research Institute Full time

    About the Role:The Scripps Research Institute is seeking an experienced Research Scientist/Senior Research Scientist to lead projects focused on immuno-oncology. This position offers hands-on training in translational research and exposure to various projects across the institute, covering infectious diseases, metabolic disorders, autoimmunity, and more. The...

  • Research Scientist

    3 weeks ago


    San Diego, California, United States Scripps Research Full time

    Scripps Research is a nonprofit biomedical institute ranked as one of the most influential in the world for its impact on innovation. We are celebrating our legacy in biomedicine, fostering groundbreaking research that transforms human health worldwide.About UsOur history spans over 100 years, marked by seminal discoveries in immunology, infectious diseases,...


  • San Francisco, California, United States Pharmatech Associates Full time

    Pharmatech Associates is an equal opportunity employer committed to fostering a professional, inclusive, and diverse environment. We are currently seeking a Principal Engineer Consultant, Cell/Gene Therapy for remote project work.Location: San Francisco, CAFull RemoteThis role will be approximately 10 – 12 hours per week over the next 6 months. As a...


  • San Diego, California, United States CV Library Full time

    About the RoleWe are seeking a highly skilled Technical Project Manager to join our team at LanceSoft. As a key member of our operations, you will play a critical role in providing technical support for analytical and process equipment for Gene Therapy operations.Key ResponsibilitiesManage the retirement planning and execution of approximately 1,500...


  • San Diego, California, United States The Scripps Research Institute Full time

    About UsThe Scripps Research Institute is a world-renowned translational research institute dedicated to advancing the next generation of medicines. We foster a unique scientific environment that combines biomedical research with cutting-edge drug discovery and development capabilities.Position OverviewWe are seeking a highly skilled Chief Virology Research...


  • San Francisco, California, United States Skills Alliance Full time

    About the RoleAt Skills Alliance, we are seeking an experienced Senior Scientific Leader to lead our gene editing research efforts. As a key member of our Preclinical Group, you will be responsible for designing and executing scientifically rigorous in vitro and in vivo studies to advance our therapeutic programs towards IND-enablement.The ideal candidate...


  • San Diego, California, United States CV Library Full time

    Job OverviewWe are seeking a highly skilled Equipment Retirements Specialist to join our team at LanceSoft. As an essential member of our operations, you will play a critical role in ensuring the smooth retirement of analytical and process equipment for Gene Therapy operations.


  • San Francisco, California, United States Lifelancer Full time

    About CytivaCytiva is a leading provider of life sciences solutions and services. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.Salary InformationThe estimated salary range for this role is $100,000 - $125,000 annually.Job DescriptionThis role will...


  • San Francisco, California, United States University of California - San Francisco Full time

    **Job Summary**The McManus Lab at the University of California, San Francisco seeks a skilled Laboratory Specialist to join our team. This full-time position offers an excellent opportunity for individuals interested in working with laboratory mice and contributing to cutting-edge research.**About Us**The McManus Lab is a dynamic and collaborative...


  • San Diego, California, United States Eurofins GSC Poland Sp. z o. o. Full time

    Job SummaryWe are seeking a highly skilled Senior RNA Manufacturing Process Development Specialist to join our Cell & Gene Therapy team in La Jolla, CA. As a key member of our team, you will be responsible for supporting RNA manufacturing process development by assisting in RNA purification and chromatographic studies.