Senior Manager, IT Lab Systems Expert
1 month ago
Verve Therapeutics, Inc. is a clinical-stage genetic medicines company dedicated to solving the global health epidemic of cardiovascular disease. Our mission is to transform treatment from chronic management to single-course gene editing medicines. We are pioneering a new approach to the care of cardiovascular disease, with an initial focus on genes that have been extensively validated as targets for lowering low-density lipoprotein cholesterol (LDL-C).
The Position
We are seeking an experienced Senior Manager, IT Lab Systems to join our team. This person will be the IT owner for both validated and non-validated lab environments, combining leadership with hands-on engineering responsibilities. The successful candidate will support and validate lab systems, working closely with both IT and business stakeholders. Additionally, they will manage vendor relationships, optimize lab data practices, ensure compliance with backup policies, and address lab-related IT escalations. Collaborating with Lab Operations, they will oversee instrument lifecycle management while mentoring service desk staff to ensure seamless support of lab IT systems.
Key Responsibilities- Translate business needs into technical solutions, working closely with Research and Development (R&D), Manufacturing, and the Lab Operations team.
- Lead IT projects from concept to implementation, including timelines, resources, and budgets, ensuring alignment with business objectives.
- Collaborate with Lab Operations to manage the instrument lifecycle (procurement, implementation, maintenance, and decommissioning).
- Ensure all R&D IT solutions comply with GxP regulatory requirements and internal policies.
- Streamline and enhance data management practices within the lab to improve data flow, accuracy, and compliance.
- Maintain compliance with backup policies and data retention requirements, ensuring data recoverability and resiliency.
- Provide technical support for Next Generation Sequencing (NGS) instruments, ensuring seamless integration with lab IT systems and processes.
- Handle lab-based IT escalations, providing technical support and troubleshooting.
- Manage, maintain, and troubleshoot key lab systems, including Empower, OpenLab, Waters Connect, and Unicorn.
- Leverage technical expertise to provide mentorship to junior team members.
- Bachelor's degree in computer sciences or engineering field with at least 7 years related experience in the biotech or pharmaceutical industry preferred.
- Required certifications: CompTIA Network+ or similar certification, CompTIA Security+ or similar certification.
- Strong communication skills, capable of effectively interfacing with both business stakeholders and technical teams.
- Proven ability to collaborate and engage with individuals across all organizational levels.
- Experience with AWS Storage Gateway and other cloud-based storage solutions.
- Deep understanding of 21 CFR Part 11, software validation, and GxP compliance, particularly in QC and manufacturing environments.
- Experience handling Big Data, especially in genomic sequencing.
- Skilled in training and mentoring support staff on lab systems and processes.
- Proficient in troubleshooting and maintaining equipment such as HPLCs, Mass Spectrometers, and Illumina Sequencers.
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