Senior Research Associate
9 hours ago
Job Title: Senior Research Associate - Biology - Immuno Oncology II
Location: Foster City, CA
Job Type: Full-time
Job Summary
ACL Digital is seeking a highly motivated and talented Senior Research Associate to join our Immuno-oncology group. Our team utilizes cutting-edge technologies and innovative methodologies to advance medicines into the clinic. The successful candidate will contribute to the discovery, research, and development of novel immunotherapeutic agents to address unmet medical needs of cancer patients.
Key Responsibilities
• Independently plan, execute, analyze, and interpret in vitro and in vivo immunological assays that support the initiation and/or advancement of drug candidate projects.
• Proactively evaluate new technologies and develop new assays to accelerate early-stage discovery activities and/or enhance our understanding of disease mechanisms.
• Manage multiple projects simultaneously and work cross-functionally with colleagues in the oncology, protein engineering, chemistry, translational medicine, biomarker, and clinical groups.
• Presents research findings and recommendations to senior staff and contribute to the preparation of research reports, manuscripts, INDs, and patent filings.
Requirements
• Master's degree with 3+ years of experience, or Bachelor's degree with 5+ years of experience in immunology, immuno-oncology, cell biology, molecular biology, or biochemistry in industry or academia.
• Direct experience in research drug discovery and target identification/validation in oncology or immuno-oncology is highly desirable.
• Strong understanding of immune cell biology, including T cell and myeloid cells.
• Proficiency in primary T cell-based functional assays such as activation, proliferation, and cytotoxicity.
• Experience in conducting and optimizing cell-based assays, as well as performing studies to assess immune responses in human and animal models (including whole blood, PBMCs, and various primary cell subsets).
• Hands-on experience in general molecular and cell biology methods, including mammalian cell culture, multi-color flow cytometry, western blot, ELISA/Luminex/MSD, and CRISPR technology.
• Attention to detail with excellent organizational and record-keeping skills is a requirement.
• Excellent communication and interpersonal skills are required.
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