Computational Genomics Senior Research Specialist
3 weeks ago
**Job Title:** Computational Genomics Senior Research Specialist
We are seeking a highly skilled computational biologist to join our team at Vertex Pharmaceuticals. This position is part of a rapidly growing data and computational sciences team focused on developing therapies for diseases with serious unmet need.
You will play a critical role in developing cutting-edge computational methods that assess the safety and efficacy of transformative therapeutics. You will also collaborate cross-functionally to develop robust and scalable workflows that address strategic questions across our programs.
The ideal candidate will have a strong background in computational methods development, proven Python programming skills, and excellent collaboration abilities.
This is a hybrid position requiring 3 days/week onsite in Boston.
Key Responsibilities:
- Develop novel computational methods to address key questions regarding the efficacy, safety, and integrity of cell therapies via NGS data analysis.
- Leverage best practices from genomics, data science, and software engineering to create industry-leading analysis software.
- Collaborate with project teams and DCS members to identify key needs and questions that can be addressed using genomics.
- Lead rigorous computational analyses of NGS and other biological data while developing new approaches.
Requirements:
- Ph.D. (or equivalent degree) in computational biology, bioinformatics, human genetics, genomics, systems biology, bioengineering, or a related field and 2-5 years of productive post-doctoral employment experience, or
- MS (or equivalent degree) in similar fields and 5+ years of productive employment experience, or
- BS (or equivalent degree) in similar fields and 8+ years of productive employment experience.
- A proven track record of next-generation sequencing (NGS) methods development pertaining to variant calling, RNA-Seq, or related data types.
- Strong programming skills in Python and one or more of the following languages: Rust, Java, or C/C++, and proficiency with workflow languages such as Nextflow.
- Strong organizational and time-management skills.
- An independent, detail-oriented, and self-motivated approach to problem solving.
- A team-oriented mindset that welcomes feedback and supports others.
- Excellent communication skills that can be tailored to scientists with or without computational biology expertise.
Estimated Salary Range: $120,000 - $160,000 per year, depending on experience.
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