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Research Scientist

2 months ago


Somerville, Massachusetts, United States Mass General Brigham Full time
Research Fellow Position in Molecular Biology with Immunology Experience

The Manstein Laboratory at Massachusetts General Hospital is conducting research in dermatology, focusing on the development of novel, energy-based procedures for the treatment of various skin conditions, including scars, burns, aging skin, and fat removal. We are inviting applications for a dedicated and innovative Research Fellow with a strong foundation in Molecular Biology and Immunology.

Responsibilities:
  • Conduct high-level research into molecular mechanisms underpinning skin health, disease, and treatment outcomes, focusing on cellular and molecular biology and immunology techniques.
  • Implement molecular biology techniques to explore the genetic and epigenetic contribution involved in skin conditions, leveraging knowledge of immunology to understand inflammatory responses and healing processes.
  • Utilize and develop in vitro and in vivo models, including mouse models, to study the effects of novel dermatological treatments.
  • Employ a variety of molecular and cellular assays to assess treatment efficacy, mechanism of action, and safety profiles.
  • Collaborate closely with a multidisciplinary team to integrate molecular findings with clinical insights, aiming to translate research into tangible medical device solutions.
  • Stay in touch with the latest scientific advancements in molecular biology, immunology, and dermatology to inform experimental design and innovation.
  • Contribute to the drafting and submission of research manuscripts for publication in high-impact journals and prepare grant proposals to secure funding.
  • Engage in knowledge exchange within the lab and broader scientific community, presenting research outcomes at conferences and workshops.
Qualifications:
  • A Ph.D. in Molecular Biology, Biochemistry, or a closely related field, with coursework or research experience in Immunology.
  • Demonstrable experience in molecular biology techniques (e.g., PCR, RT-qPCR, Western blotting, CRISPR-Cas9, RNA sequencing).
  • Familiarity with immunological assays and concepts, particularly those relevant to dermatological research.
  • Proven track record of conducting animal studies, preferably with experience in mouse models, including handling, surgery, and post-operative care.
  • Solid understanding of data analysis software and bioinformatics tools relevant to molecular biology and immunology.
  • Exceptional written and verbal communication skills, with the ability to present complex data to diverse audiences.
  • Capacity to work both independently and collaboratively within a multidisciplinary research team.
Preferred Qualifications:
  • Previous experience with laser-based devices or photochemical assays.
  • Background in dermatological research or a keen interest in dermatology and skin biology.
  • Evidence of successful publication in peer-reviewed journals.
  • Ability to manage multiple projects and adapt to shifting priorities in a research environment.
Position Details:

This is a full-time role offering a competitive salary (above NIH post doc stipend levels) and benefits package, matching experience, and qualifications. Located within the research community of Massachusetts General Hospital Harvard Medical School, the Manstein Lab provides an exceptional environment for scientific growth and discovery.

If you are passionate about molecular biology and immunology within dermatology and eager to contribute to developing innovative medical solutions, please submit your application. Include your resume and a cover letter highlighting your relevant experience and interests.

Applications will be reviewed on a rolling basis until the position is filled. We thank all applicants for their interest; however, only those selected for an interview will be contacted.