Upstream Process Development Lead
7 days ago
We are seeking an experienced Gene Therapy Scientist to lead our late-stage upstream process development efforts for AAV gene therapy programs in Redwood City, CA.
Main Responsibilities:- Develop and optimize scalable upstream processes for AAV production, ensuring reproducibility, scalability, and compliance with regulatory standards.
- Collaborate with cross-functional teams to design and execute experiments to optimize cell culture conditions, transfection parameters, and bioreactor performance.
- Design, develop, and implement scalable upstream processes compatible with GMP requirements, including suspension cell culture systems.
The ideal candidate will have a Ph.D. in Biochemistry, Chemical Engineering, Molecular Biology, or related field with 6+ years of relevant experience in upstream process development; or M.S. with 8+ years of experience.
Benefits:This role offers a competitive salary range of $160,000 USD to $185,000 USD annually, with the opportunity to earn an annual bonus. Employees in this position are eligible to participate in the applicable Company equity incentive award plan and standard employee benefit programs, which currently include medical, dental, vision, 401k, STD/LTD, life and accident insurance, and either paid time off or flexible paid time off.
About Us:Adverum Biotechnologies, Inc. is a clinical-stage gene therapy company targeting unmet medical needs in ophthalmology and rare diseases. We strive to create a workplace where everyone can feel safe and encouraged to speak, learn from each other, grow in their professions and be the best versions of themselves.
Requirements:- Proven experience in AAV or other viral vector production, particularly in late-stage development for clinical/commercial scale manufacturing.
- Strong expertise in cell culture, bioreactor design and operation, and viral vector transfection techniques.
We estimate the average salary for this position to be around $172,500 USD per year, based on industry standards and the location of Redwood City, CA.
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