Computational Chemistry Lead

3 days ago


Oklahoma City, Oklahoma, United States Entactbio Full time

Job Title: Computational Chemistry Lead

Location: Watertown, MA

We are seeking a highly skilled computational chemist to join our Molecular Discovery group at Entactbio. As a key member of our team, you will be responsible for shaping our computational chemistry strategy and driving programs from hit discovery to development candidate selection.

About the Role:

  • Leverage structure-based methods to design and prioritize compounds in collaboration with chemistry, structural biology, and Lead Discovery groups
  • Design and execute virtual screening campaigns
  • Develop models to predict properties of bRo5 compounds
  • Work with leadership to develop strategy for employing computational chemistry at Entactbio

Your Background:

  • Ph.D. in computational chemistry or related field with 7+ years of experience in the drug industry
  • Expert-level knowledge of modern concepts in computational drug discovery, including docking, pharmacophore-based drug design, and water map
  • Experience with cheminformatics and compound library design a plus

Compensation: $150,000 - $180,000 per year, depending on experience



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