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Genomics Research Associate

2 months ago

Houston, Texas, United States Baylor College of Medicine Full time
Position Overview

The Human Genome Sequencing Center (HGSC) at Baylor College of Medicine, established in 1996, is recognized globally for its pioneering work in genomics. The center's core mission is to facilitate actionable translational research that spans the entire spectrum of human health and disease. By leveraging extensive genomic data, the HGSC aims to enhance collaborative analytics, discover gene-phenotype relationships, and drive clinical advancements.

In alignment with the National Institutes of Health Common Fund initiative known as the Somatic Mosaicism across Human Tissues (SMaHT) Network, the HGSC is set to create a Genome Characterization Center (GCC). This center will employ cutting-edge methodologies and innovate new techniques to catalog the prevalence of somatic mosaicism across various cell types, tissues, and developmental stages, ultimately aiming to elucidate its impact on human biology and disease.

Key Responsibilities
  • Designs, manages, and executes specialized and advanced research experiments.
  • Develops and implements new laboratory research protocols and procedures. Assesses various library and sequencing methodologies and interprets data.
  • Optimizes and scales new DNA and RNA library preparation and sequencing techniques.
  • Compiles research findings and disseminates results through publications in scientific journals.
  • Conducts comprehensive literature reviews and synthesizes information relevant to specific studies.
  • Monitors quality control measures on sequencing data, resolves technical challenges, and maintains data integrity throughout the research process.
  • Records experimental outcomes, generates reports, and presents findings at both internal and external meetings.
  • Oversees, organizes, and coordinates the activities of junior research personnel.
Qualifications
  • MD or Ph.D. in Basic Science, Health Science, or a related discipline.
  • No prior experience is necessary.
Preferred Skills
  • Demonstrated expertise in developing novel laboratory genomics methodologies; experience with somatic mutation sequencing and duplex sequencing.
  • Practical knowledge of qPCR and ddPCR techniques.
  • Familiarity with bioinformatics tools and applications.

Baylor College of Medicine is committed to fostering a diverse and inclusive workplace.