Senior Large Molecule Bioanalysis Method Development Expert

2 weeks ago


Exton, Pennsylvania, United States Frontage Laboratories Full time

Job Summary:

The Senior Method Development Scientist plays a key role in supporting the development of bioanalytical methods for large molecules using LC-MS/MS technology. This position requires a strong background in analytical chemistry, biochemistry, or a related field, with a focus on mass spectrometry method development for antibodies, protein quantitation, and conjugate analysis.

Key Responsibilities:

  • Develop and optimize bioanalytical methods for large molecules using LC-MS/MS technology
  • Collaborate with cross-functional teams to ensure method transfer and validation
  • Communicate project timelines, status, and data to stakeholders
  • Stay up-to-date with industry trends and advancements in mass spectrometry and bioanalytical methods
  • Maintain regulatory compliance and ensure adherence to GLP regulations and SOPs
  • Train and mentor junior scientific staff
  • Operate and maintain complex instrumentation

Requirements:

  • Ph.D. or Master's degree in Analytical Chemistry, Biochemistry, Biology, or a related scientific discipline
  • 6-10 years of direct experience in bioanalytical method development for large molecules using LC-MS/MS in the biotech, pharma, or CRO industry
  • Demonstrated experience in mass spectrometry method development for antibodies, including LC-MS intact protein analysis, peptide mapping, and conjugate analysis
  • Experience with oligonucleotides and liposomal drug quantitation using LC-MS/MS is a plus
  • Proven ability to work in a team environment and communicate effectively
  • Strong analytical and troubleshooting skills
  • Detail-oriented and meticulous

Benefits:

  • Competitive compensation and benefits package
  • Health and dental insurance
  • 401(k) plan
  • Short and long-term disability insurance
  • Life insurance

Equal Opportunity Employer:

Frontage Laboratories is an equal opportunity employer and welcomes applications from qualified candidates without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, or disability status.



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