Lead Electron Microscopy Scientist
1 week ago
Position Overview:
The Senior Staff Scientist role is available within the FIB-SEM Collaboration Core (F-SCC) at Yale School of Medicine. This position is pivotal in advancing volume Electron Microscopy, leveraging cutting-edge Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) technology for extensive imaging with nanometer isotropic resolution. Reporting to the Director of F-SCC, the selected candidate will take on a leadership position in overseeing the electron microscopy (EM) sample preparation laboratory within F-SCC.
Key Responsibilities:
The candidate will be tasked with enhancing current EM sample preparation protocols for biological specimens and innovating new methodologies for clinical samples. Responsibilities include:
- Executing EM sample preparation requests across a variety of biological and human samples, utilizing the reduced Osmium Tetroxide-Thiocarbohydrazide-Osmium (rOTO) protocols to ensure optimal sample quality in terms of ultrastructure preservation, membrane contrast, and resin infiltration.
- Conducting transmission electron microscopy (TEM) thin section preparation and imaging to assess sample quality.
- Optimizing existing EM sample preparation protocols to enhance ultrastructure preservation and sample contrast.
- Establishing transcardial perfusion operations on animal models.
- Developing innovative methods for clinical specimen preparation.
- Creating an automated EM sample preparation pipeline.
- Performing FIB-SEM sample preparation, which encompasses sample mounting and precise targeting of specific regions of interest using ultramicrotome guidance and x-ray micro-CT.
Essential Duties:
- Conducting a wide array of specialized scientific techniques and procedures in the laboratory.
- Managing resource planning, allocation, and laboratory renovations, while establishing and implementing the operational framework aligned with long-term objectives.
- Staying updated on emerging technologies, instrumentation, and methodologies, including procurement of new instruments.
- Developing, analyzing, interpreting, and summarizing scientific findings.
- Establishing policies and procedures governing laboratory operations.
- Independently addressing and resolving biotechnological challenges through research and comprehensive literature reviews.
- Determining when additional analyses are necessary, coordinating those analyses, and interpreting the resulting data to implement tailored protocols.
- Authorizing and organizing laboratory and equipment usage to ensure timely project completion.
- Performing additional duties as assigned.
Qualifications:
A Master's Degree in chemistry, biology, biochemistry, or a related field, accompanied by five years of relevant experience, or an equivalent combination of education and experience is required.
Required Skills:
- Proficiency in developing new EM sample preparation protocols and implementing automated pipelines to support advancements in volume electron microscopy.
- Ability to research and interpret scientific literature, protocols, and standard operating procedures.
- Experience in operating and modifying laboratory instruments for enhanced performance and troubleshooting.
- Capacity to anticipate project requirements and strategically plan resource allocation for successful project execution.
- Skill in maintaining laboratory facilities and adapting to new procedures as needed.
Preferred Qualifications:
A Ph.D. in biology, chemistry, biochemistry, or a related discipline, along with five years of pertinent experience, is preferred. Candidates with a strong background in EM sample preparation, a keen interest in automation, and certification as an Electron Microscopy Technologist will be given special consideration.
Work Schedule:
Occasional weekend and evening hours may be required.
Background Check:
All candidates will undergo pre-employment background screening, which may include various checks based on job requirements.
EEO Statement:
Yale University is committed to affirmative action in employment and does not discriminate based on sex, sexual orientation, gender identity, race, color, national or ethnic origin, religion, age, disability, or veteran status.
-
Lead Electron Microscopy Scientist
2 weeks ago
New Haven, Connecticut, United States Yale University Full timePosition Overview: The Senior Research Scientist role is available within the FIB-SEM Collaboration Core at Yale University. This position is pivotal in advancing volume Electron Microscopy, utilizing cutting-edge Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) technology for extensive imaging with nanometer isotropic resolution. Reporting to the...
-
Lead Electron Microscopy Scientist
1 week ago
New Haven, Connecticut, United States Yale University Full timePosition Overview: The Senior Staff Scientist role is available within the FIB-SEM Collaboration Core (F-SCC) at Yale School of Medicine. This position is pivotal in advancing volume Electron Microscopy through the utilization of cutting-edge Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) technology, enabling large volume imaging with nanometer...
-
Senior Staff Scientist
2 days ago
New Haven, Connecticut, United States Yale University Full timeJob Summary:The Yale University is seeking a highly skilled and experienced Senior Staff Scientist to join the FIB-SEM Collaboration Core (F-SCC) team. As a key member of the team, the successful candidate will play a leadership role in managing the electron microscopy (EM) sample preparation lab and contribute to the development of new methods for clinical...
-
Scientist I
8 hours ago
New Haven, Connecticut, United States eTeam Full timeAbout the RoleWe are seeking a highly skilled Scientist I to join our Injectable Drug Product Development group in the Analytical and Pharmaceutical Development department at eTeam.As a Scientist I, you will be responsible for conducting studies to enable Drug Product characterization activities, including combination products at high protein concentration,...
-
Lead Histotechnologist
2 weeks ago
New Haven, Connecticut, United States Yale School of Medicine Full timePosition Overview: This role is accountable for overseeing the daily operations of the Histology department, reporting directly to the Senior Manager of Histology, Outreach Histology, and Immunohistochemistry. The incumbent will be responsible for recruiting qualified personnel, assessing performance, and implementing necessary disciplinary actions in...
-
Scientist I: Protein Characterization
4 weeks ago
New Haven, Connecticut, United States Proclinical Full timeScientist I - Protein Characterization - Contract - New Haven CTProclinical is seeking a dedicated and innovative Protein Characterization Specialist. Primary Responsibilities:The successful candidate will be responsible for leading and performing protein characterization, overseeing and training associates, participating in cross-functional development...
-
Junior Scientist I
2 weeks ago
New Haven, Connecticut, United States ADPI Full timePosition Title: Junior Scientist IContract Duration: 12 Month ContractLocation: New Haven, CT - Onsite RequirementRole Overview: This position is integral to the Injectable Drug Product Development team within the Pharmaceutical Development and Clinical Supply (PDCS) department, focusing on Rare Disease Pharmaceuticals.Key Responsibilities:Assist in the...
-
Clinical Laboratory Scientist
2 weeks ago
New Haven, Connecticut, United States Yale New Haven Health Full timePosition Overview:At Yale New Haven Health, we believe that every team member should embody our Vision, support our Mission, and uphold our Values of integrity, patient-centered care, respect, accountability, and compassion. These principles guide our actions as professionals every day.As a Medical Laboratory Scientist specializing in the Blood Bank, you...
-
Sr Associate Scientist, In-Vivo
2 months ago
New Haven, Connecticut, United States Arvinas Inc. Full timeArvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Arvinas uses its proprietary PROTAC Discovery Engine platform to engineer proteolysis targeting...
-
New Haven, Connecticut, United States Biomedx Full timeAbout BioMed XBioMed X is a cutting-edge research institute that operates at the intersection of academia and industry. Our mission is to advance translational biomedicine by leveraging synergies and fostering cross-pollination across disciplines.We are a global organization with a network of partner locations, and our research projects are sponsored by...
-
Senior Research Scientist
6 days ago
West Haven, Connecticut, United States CPS Full timeJob SummaryThis is a senior research scientist position working at the bench and pilot plant to support the development strategy of the bakery business. The successful candidate will be responsible for leading new product development, working with suppliers and contract manufacturing, and providing technical support to internal groups and external...
-
New Haven, Connecticut, United States BioCT Innovation Commons Full timeAbout the Role**Job Summary**We are seeking a highly experienced Senior Principal Scientist to lead our Gene Editing Analytical and Control Strategy Development team at BioCT Innovation Commons. As a key member of our Synthetic Product Development organization, you will be responsible for delivering phase-appropriate control strategies for our gene editing...
-
Manager of Histology Services
2 weeks ago
New Haven, Connecticut, United States Yale School of Medicine Full timePosition Overview: This role is integral to the operations of the Histology department, reporting directly to the Senior Manager of Histology, Outreach Histology, and Immunohistochemistry. The incumbent will be responsible for recruiting qualified personnel, conducting evaluations, and, when necessary, initiating disciplinary actions in accordance with Human...
-
Tenure Track Faculty
1 month ago
New Haven, Connecticut, United States Yale School of Medicine - Ludwig Program for the Study of Neuroimmune Interactions in Dementia Full timeThe newly established Carol and Gene Ludwig Program for the Study of Neuroimmune Interactions in Dementia at Yale School of Medicine seeks to hire a new tenure track faculty member researching neuroinflammation in Alzheimer's Disease or related dementias. We are enthusiastic about candidates bridging disciplines and traditional conceptual or methodological...
-
Tenure Track Faculty
1 month ago
New Haven, Connecticut, United States Yale University School of Medicine - Department of Neuroscience Full timeThe Department of Neuroscience at Yale University seeks to hire new tenure track faculty members with interests in molecular, cellular, systems, cognitive, computational or theoretical neuroscience in health or disease. We are enthusiastic about candidates bridging between traditional conceptual or methodological boundaries, and candidates linking...
-
New Haven, Connecticut, United States Yale School of Medicine, Department of Neuroscience Full timePosition Overview:The Department of Neuroscience at Yale School of Medicine is actively seeking to appoint new tenure track faculty members who possess expertise in various domains of neuroscience, including molecular, cellular, systems, cognitive, computational, or theoretical neuroscience, particularly in relation to health and disease. Candidate...
-
Senior Research Scientist
4 days ago
West Haven, Connecticut, United States Cps4jobs Full timeAbout the RoleCps4jobs is seeking a highly skilled Senior Research Scientist to join our Bakery Development team. As a key member of our R&D team, you will be responsible for driving innovation and product development in the bakery and grains industry.Key ResponsibilitiesDevelop and implement new product concepts and formulations to meet business...
-
New Haven, Connecticut, United States K.A. Recruiting Full timeExciting Opportunity for a Clinical Laboratory Specialist Join a prestigious healthcare institution known for its excellence in patient care and recognized as a 'High Performing Hospital' by industry standards. This facility is a 300-bed institution that has earned accolades for being a Great Place to Work and is Magnet Recognized. We are seeking a dedicated...
-
Histology Laboratory Supervisor
2 weeks ago
New Haven, Connecticut, United States Yale School of Medicine Full timePosition Overview: This role is integral to the management of the Histology Laboratory, reporting directly to the Senior Manager of Histology, Outreach Histology, and Immunohistochemistry. The incumbent will be responsible for recruiting qualified personnel, conducting evaluations, and, when necessary, initiating disciplinary actions in accordance with Human...
-
MRI RF Engineer
2 weeks ago
New Haven, Connecticut, United States Yale University Full timeJob Summary:The Yale University MRI RF Engineer will be a key member of a dynamic team of scientists and engineers in the Yale Magnetic Resonance Research Center. The successful candidate will be responsible for designing and developing novel low-cost MRI systems, with a focus on transmit and receive RF coil design, preamplifiers, and other receive chain...
