Bioinformatics Scientist

2 days ago


Palo Alto, California, United States Guardant Health Full time

About Us
Guardant Health is a global leader in precision oncology, dedicated to harnessing the power of data and technology to improve patient outcomes. Our innovative approach combines cutting-edge testing, advanced analytics, and collaborative partnerships to deliver high-quality diagnostic solutions.

The Role
We are seeking a highly skilled technical lead in bioinformatics and molecular diagnostics to join our team. As a key member of our scientific leadership team, you will drive strategic initiatives, nurture talent, and establish standards that inspire and guide your colleagues. Your expertise in software development, regulatory compliance, molecular biology, and quality systems will enable you to make a significant impact on our business outcomes.

Key Responsibilities
Design and validate experimental protocols in collaboration with Technology Development
Architect and enhance bioinformatics algorithms powering new diagnostic development and existing production workflows
Lead technical initiatives hands-on while mentoring teams in building robust, scalable bioinformatics pipelines
Develop data management strategies optimizing product performance and empowering cross-team collaboration
Evaluate cost-benefit analyses for performance improvements and COGS reduction
Stay current with cutting-edge sequencing technologies and computational methods
Build consensus across scientific, quality, regulatory, and business teams to align priorities with user needs
Guide complex projects from conception to completion, anticipating challenges and ensuring timely delivery

Requirements
PhD level with 10+ years related industry experience
Expert experience with data and statistical analysis using Python
Expert developing bioinformatics pipelines in one or more languages (e.g., Python, R, Java, C++, Rust)
Comfortable developing in cloud environments and using workflow managers
5+ years managing and troubleshooting genetic sequencing assays or tests
Statistical design for experiments for development and validation of diagnostics in a regulated environment (e.g., CAP/CLIA, FDA)
Ability to design well-tested software that interfaces in larger systems and is extensible by other team members and teams
Proven mentor and leader of teams that have successfully developed and launched medical diagnostics

About the Opportunity
This role offers a unique chance to shape the future of precision oncology and lead high-impact initiatives. We offer a competitive salary range of $173,600 - $234,300, depending on location and experience, as well as a hybrid work model that balances in-person collaboration and focused individual time. If you are a motivated and experienced bioinformatics scientist looking to take on a leadership role, we encourage you to apply.



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